Trafermin
Trafermin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetic foot | D017719 | EFO_1001459 | — | — | — | 2 | — | — | 2 |
| Ulcer | D014456 | MPATH_579 | — | — | — | 2 | — | — | 2 |
| Foot ulcer | D016523 | — | — | — | — | 2 | — | — | 2 |
Indications Phases 2
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Trafermin |
| INN | trafermin |
| Description | Trafermin (brand name Fiblast), also known as recombinant human basic fibroblast growth factor (rhbFGF), is a recombinant form of human basic fibroblast growth factor (bFGF) which is marketed in Japan as a topical spray for the treatment of skin ulcers. It is also currently in preregistration for the treatment of periodontitis. As a recombinant form of bFGF, trafermin is a potent agonist of the FGFR1, FGFR2, FGFR3, and FGFR4. The drug has been marketed in Japan since June 2001.
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| Classification | Protein |
| Drug class | growth factors: fibroblast growth factors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 131094-16-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108081 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB06244 |
| UNII ID | 333OX80X87 (ChemIDplus, GSRS) |
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