Tinzaparin sodium
Innohep (tinzaparin sodium) is an oligosaccharide pharmaceutical. Tinzaparin sodium was first approved as Innohep on 2000-07-14. It is used to treat pulmonary embolism, thromboembolism, and venous thrombosis in the USA. The pharmaceutical is active against antithrombin-III.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| respiratory tract diseases | D012140 |
| cardiovascular diseases | D002318 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Tinzaparin sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| INNOHEP | LEO Pharma | N-020484 DISCN | 2000-07-14 | 1 products |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| innohep | 2008-04-14 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| venous thrombosis | HP_0004936 | D020246 | I82.40 |
| pulmonary embolism | HP_0002204 | D011655 | I26 |
| thromboembolism | HP_0001907 | D013923 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J1655 | Injection, tinzaparin sodium, 1000 iu |
Clinical
Clinical Trials
560 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thromboembolism | D013923 | HP_0001907 | — | 2 | 14 | 53 | 28 | 60 | 153 |
| Thrombosis | D013927 | — | — | 3 | 16 | 35 | 29 | 57 | 135 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | 2 | 11 | 38 | 21 | 51 | 120 |
| Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | 11 | 26 | 22 | 34 | 90 |
| Embolism | D004617 | — | — | 1 | 3 | 18 | 20 | 20 | 61 |
| Covid-19 | D000086382 | — | — | 1 | 13 | 16 | 7 | 25 | 59 |
| Pulmonary embolism | D011655 | HP_0002204 | I26 | 1 | 2 | 17 | 20 | 20 | 59 |
| Neoplasms | D009369 | — | C80 | 1 | 5 | 11 | 3 | 16 | 35 |
| Syndrome | D013577 | — | — | 4 | 7 | 7 | 5 | 5 | 26 |
| Hemorrhage | D006470 | MP_0001914 | R58 | 1 | 1 | 3 | 4 | 10 | 19 |
Show 88 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 2 | 4 | 2 | — | 4 | 11 |
| Plasma cell neoplasms | D054219 | — | — | 2 | 4 | 2 | — | 4 | 11 |
| Colorectal neoplasms | D015179 | — | — | — | 1 | 4 | — | 2 | 7 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | 1 | — | 3 | — | 3 | 7 |
| Hemostatic disorders | D020141 | — | — | 1 | — | 3 | — | 3 | 7 |
| Intracranial thrombosis | D020767 | — | — | — | 2 | 3 | — | 1 | 5 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 2 | 1 | — | 1 | 4 |
| Lymphoma | D008223 | — | C85.9 | — | 2 | 1 | — | 1 | 4 |
| Viral pneumonia | D011024 | EFO_0007541 | J12.9 | — | — | 2 | — | 2 | 4 |
| Pre-eclampsia | D011225 | EFO_0000668 | O14 | — | 1 | 3 | — | 1 | 4 |
Show 62 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | — | — | 3 | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 2 | — | — | 1 | 3 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | 1 | — | — | 1 | 2 |
| Iga vasculitis | D011695 | EFO_1000965 | D69.0 | 1 | 1 | — | — | 1 | 2 |
| Purpura | D011693 | HP_0000979 | D69.2 | 1 | 1 | — | — | 1 | 2 |
| Percutaneous coronary intervention | D062645 | — | — | — | 1 | — | — | 1 | 2 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 2 | 1 | — | — | — | 2 |
| Ovarian epithelial carcinoma | D000077216 | — | — | — | 2 | — | — | — | 2 |
| Spinal cord injuries | D013119 | EFO_1001919 | — | — | 1 | — | — | — | 1 |
| Duodenal neoplasms | D004379 | — | — | — | 1 | — | — | — | 1 |
Show 30 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 6 | — | — | — | — | 6 |
| Pregnancy rate | D018873 | — | — | 1 | — | — | — | 1 | 2 |
| Blood platelet disorders | D001791 | — | — | 1 | — | — | — | — | 1 |
| Balloon angioplasty coronary | D015906 | EFO_0003951 | — | 1 | — | — | — | — | 1 |
| Stillbirth | D050497 | — | P95 | 1 | — | — | — | — | 1 |
| Clear cell sarcoma | D018227 | — | — | 1 | — | — | — | — | 1 |
| Pseudotumor cerebri | D011559 | EFO_1001132 | G93.2 | 1 | — | — | — | — | 1 |
| Intracranial hypertension | D019586 | EFO_1000992 | — | 1 | — | — | — | — | 1 |
| Systemic lupus erythematosus | D008180 | HP_0002725 | M32 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative complications | D011183 | — | — | — | — | — | — | 4 | 4 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 4 | 4 |
| Heart valve diseases | D006349 | EFO_0009551 | I08 | — | — | — | — | 2 | 2 |
| Length of stay | D007902 | — | — | — | — | — | — | 2 | 2 |
| Connective tissue diseases | D003240 | EFO_1001986 | M35 | — | — | — | — | 2 | 2 |
| Blood coagulation | D001777 | GO_0007596 | — | — | — | — | — | 2 | 2 |
| Fertilization in vitro | D005307 | — | — | — | — | — | — | 2 | 2 |
| Esophageal and gastric varices | D004932 | EFO_0009545 | I85 | — | — | — | — | 2 | 2 |
| Ecchymosis | D004438 | HP_0000978 | — | — | — | — | — | 2 | 2 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | — | — | 2 | 2 |
Show 62 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Tinzaparin sodium |
| INN | tinzaparin sodium |
| Description | Tinzaparin is an antithrombotic drug in the heparin group. It is a low molecular weight heparin (LMWH) marketed as Innohep worldwide. It has been approved by the U.S. Food and Drug Administration (FDA) for once daily treatment and prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE).
|
| Classification | Peptide |
| Drug class | heparin derivatives and low molecular weight (or depolymerized) heparins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201414 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 3S182ET3UA (ChemIDplus, GSRS) |
Target
Agency Approved
SERPINC1
SERPINC1
Organism
Homo sapiens
Gene name
SERPINC1
Gene synonyms
AT3
NCBI Gene ID
Protein name
antithrombin-III
Protein synonyms
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, Serpin C1, serpin peptidase inhibitor clade C member 1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Uniprot ID
Mouse ortholog
Serpinc1 (11905)
antithrombin-III (P32261)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 2,201 documents
View more details
Safety
Black-box Warning
Black-box warning for: Innohep
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
3,132 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use