PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsSulbactam
Sulbactam
Ampicillin / Sulbactam, Unasyn, Xacduro (sulbactam) is a small molecule pharmaceutical. Sulbactam was first approved as Unasyn on 1986-12-31. It is used to treat acinetobacter infections, bacterial skin diseases, escherichia coli infections, intraabdominal infections, and klebsiella infections amongst others in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Combinations
Ampicillin sulbactam, Unasyn, Xacduro (discontinued: Ampicillin sulbactam, Unasyn)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ampicillin sodium
+
Sulbactam sodium
Tradename
Company
Number
Date
Products
UNASYNPfizerN-050608 RX1986-12-31
3 products, RLD, RS
Show 1 discontinued
Durlobactam sodium
+
Durlobactam sodium
+
Sulbactam sodium
Tradename
Company
Number
Date
Products
XACDURO (COPACKAGED)Entasis TherapeuticsN-216974 RX2023-05-23
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
ampicillin and sulbactamANDA2025-08-12
ampicillin sodium and sulbactam sodiumANDA2025-09-08
unasynNew Drug Application2025-05-14
xacduroNew Drug Application2025-03-27
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
respiratory tract infections—D012141J06.9
urinary tract infectionsEFO_0003103D014552N39.0
pneumococcal infectionsEFO_0000772D011008J13
infectious pregnancy complications—D011251—
bacterial infections—D001424A49
gonorrheaDOID_7551D006069A54
intraabdominal infections—D059413—
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
soft tissue infections—D018461—
Show 14 more
Agency Specific
FDA
EMA
Expiration
Code
DURLOBACTAM SODIUM / DURLOBACTAM SODIUM / SULBACTAM SODIUM, XACDURO (COPACKAGED), ENTASIS THERAP
2033-05-23GAIN
2028-05-23NCE
Patent Expiration
Patent
Expires
Flag
FDA Information
Durlobactam Sodium / Durlobactam Sodium / Sulbactam Sodium, Xacduro (Copackaged), Entasis Therap
99685932035-11-17DPU-2840
103764992035-11-17DPU-2840
93092452033-04-02DP
96230142033-04-02U-2840
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CG: Beta-lactamase inhibitors, systemic penicillins
— J01CG01: Sulbactam
HCPCS
Code
Description
J0295
Injection, ampicillin sodium/sulbactam sodium, per 1.5 gm
Clinical
Clinical Trials
63 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PneumoniaD011014EFO_0003106J18——1113
InfectionsD007239EFO_0000544————1—1
Communicable diseasesD003141—————1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial pneumoniaD018410EFO_1001272J15.9——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PeritonitisD010538EFO_0008588K65————22
AppendicitisD001064EFO_0007149K37————11
Wound infectionD014946——————11
CholecystitisD002764—K81————11
Abdominal abscessD018784EFO_1001753—————11
AbscessD000038EFO_0003030—————11
Lung abscessD008169EFO_1001362J85.2————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameSulbactam
INNsulbactam
Description
Sulbactam is a member of penicillanic acids.
Classification
Small molecule
Drug classbeta-lactamase inhibitors
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1(C)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O
Identifiers
PDB—
CAS-ID68373-14-8
RxCUI—
ChEMBL IDCHEMBL403
ChEBI ID9321
PubChem CID130313
DrugBank—
UNII IDS4TF6I2330 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Xacduro – Innoviva
Plot placeholder
Mock data
Subscribe for the real data
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Estimated US medical usage
Sulbactam
+
Ampicillin
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 20,847 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
3,906 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use