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Company ReportsEntasis Therapeutics

Entasis Therapeutics(ETTX)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Xacduro	Sulbactam, Durlobactam	2023-05-23	2033-2035	Respiratory tract infections , Urinary tract infections , Pneumococcal infections , Infectious pregnancy complications , Bacterial infections , Gonorrhea , Intraabdominal infections , Bacterial skin diseases , Escherichia coli infections , Soft tissue infections , Bacillary dysentery , Surgical wound infection , Staphylococcal infections , Bacterial endocarditis , Bacterial meningitis , Salmonella infections , Proteus infections , Acinetobacter infections , Listeriosis , Klebsiella infections , Meningococcal infections , Haemophilus infections , Human bites , Actinomycosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

renal insufficiency

,

healthy volunteers/patients

,

,

communicable diseases

,

urinary tract infections

,

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

bacterial pneumonia

,

,

acinetobacter infections

renal insufficiency

,

healthy volunteers/patients

,

,

communicable diseases

,

urinary tract infections

,

,

acinetobacter infections

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

bacterial pneumonia

,

,

hypersensitivity

healthy volunteers/patients

neoplasm metastasis

,

primary myelofibrosis

,

,

adrenal gland neoplasms

,

pharmacokinetics

,

depressive disorder

,

castration-resistant prostatic neoplasms

,

leukemia myeloid chronic atypical bcr-abl negative

,

,

,

pure autonomic failure

,

,

,

mandibular fractures

,

skin abnormalities

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

,

acinar cell carcinoma

,

relapsing-remitting multiple sclerosis

,

,

second primary neoplasms

,

brain neoplasms

,

,

,

major depressive disorder

,

cocaine-related disorders

,

,

essential hypertension

,

prolymphocytic leukemia

,

prolymphocytic leukemia b-cell

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

,

multiple myeloma

,

bcr-abl positive chronic myelogenous leukemia

,

hematologic neoplasms

,

plasma cell neoplasms

,

myelomonocytic leukemia juvenile

,

mantle-cell lymphoma

,

,

myelomonocytic leukemia chronic

,

refractory anemia with excess of blasts

,

myeloid leukemia chronic-phase

,

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia accelerated phase

,

myelomonocytic leukemia acute

,

diabetes mellitus

,

biphenotypic leukemia acute

,

cutaneous malignant melanoma

,

beta-thalassemia

,

,

prostatic neoplasms

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

colorectal neoplasms

,

,

type 1 diabetes mellitus

,

t-cell lymphoma

,

follicular lymphoma

,

postoperative pain

,

burkitt lymphoma

,

hematopoietic stem cell transplantation

,

replacement arthroplasty knee

,

blastic plasmacytoid dendritic cell neoplasm

,

,

graft vs host disease

,

breast neoplasms

,

pancreatic neoplasms

,

transitional cell carcinoma

,

metabolic syndrome

,

,

bronchiolitis obliterans syndrome

,

monocytic leukemia acute

,

megakaryoblastic leukemia acute

,

erythroblastic leukemia acute

,

endometrial neoplasms

,

cardiovascular diseases

,

aplastic anemia

,

pathologic complete response

,

nervous system diseases

,

congenital abnormalities

,

sickle cell anemia

,

,

,

urologic neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

non-small-cell lung carcinoma

,

merkel cell carcinoma

,

polyomavirus infections

,

glucose metabolism disorders

,

metabolic diseases

,

,

endocrine system diseases

,

bronchiolitis obliterans

,

interstitial lung diseases

,

cryptogenic organizing pneumonia

,

organizing pneumonia

,

basophilic leukemia acute

,

renal cell carcinoma

,

hepatocellular carcinoma

,

stomach neoplasms

,

head and neck neoplasms

,

thyroid neoplasms

,

esophageal neoplasms

,

urinary bladder neoplasms

,

,

uterine neoplasms

,

liver neoplasms

,

kidney neoplasms

,

uterine cervical neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

thyroid diseases

,

bacterial endocarditis

,

,

subacute bacterial endocarditis

,

,

autoimmune diseases

,

autoimmune diseases of the nervous system

,

autologous transplantation

,

neuromyelitis optica

,

myasthenia gravis

,

ocular motility disorders

,

polyneuropathies

,

muscle weakness

,

,

stiff-person syndrome

,

central nervous system vasculitis

,

spinocerebellar degenerations

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

lambert-eaton myasthenic syndrome

,

opsoclonus-myoclonus syndrome

,

,

,

orthostatic intolerance

,

b-cell lymphoma marginal zone

,

mast-cell leukemia

,

lymphoproliferative disorders

,

,

nervous system neoplasms

,

waldenstrom macroglobulinemia

,

,

bone marrow failure disorders

,

,

dyskeratosis congenita

,

stem cell transplantation

,

hematologic diseases

,

myeloid sarcoma

,

,

,

pituitary acth hypersecretion

,

cushing syndrome

,

acth-secreting pituitary adenoma

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

postural orthostatic tachycardia syndrome

,

cavernous hemangioma central nervous system

,

craniocerebral trauma

,

,

nervous system trauma

,

,

pulmonary tuberculosis

,

refractory anemia

,

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

bronchial spasm

,

alcohol drinking

,

re-epithelialization

,

local anesthesia

,

chlamydia infections

,

intracranial hemorrhages

,

cerebral hemorrhage

,

hemorrhagic stroke

,

ischemic stroke

,

cerebrovascular disorders

,

central nervous system diseases

,

,

,

pulmonary edema

,

low tension glaucoma

,

inborn genetic diseases

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

myelodysplastic syndromes

,

,

,

non-hodgkin lymphoma

,

,

myeloproliferative disorders

,

hodgkin disease

,

ulcerative colitis

,

,

philadelphia chromosome

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

bacterial pneumonia

,

multiple sclerosis

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma

,

,

,

large b-cell lymphoma diffuse

,

ventilator-associated pneumonia

,

,

,

port-wine stain

,

capillary hemangioma

,

promyelocytic leukemia acute

,

,

healthcare-associated pneumonia

,

central nervous system neoplasms

,

eyelid neoplasms

,

,

,

,

severe acute malnutrition

,

,

,

,

gata2 deficiency

,

,

iatrogenic disease

,

acinetobacter infections

,

hypersensitivity

,

,

,

enterobacteriaceae infections

,

gram-negative bacterial infections

,

,

wounds and injuries

,

traumatic brain injuries

,

,

,

coronavirus infections

,

severe acute respiratory syndrome

,

,

,

environmental biomarkers

,

community-acquired pneumonia

,

community-acquired infections

,

microbial drug resistance

,

methicillin-resistant staphylococcus aureus

,

,

,

,

intraabdominal infections

,

wound infection

,

respiratory aspiration

,

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

,

,

,

,

,

tobacco use disorder

,

smoking cessation

,

,

,

suppurative otitis media

,

,

child nutrition disorders

,

critical illness

,

,

,

gouty arthritis

,

,

ganglioneuroblastoma

,

intracranial pressure

,

,

,

,

,

communicable diseases

,

healthy volunteers/patients

,

chronic obstructive pulmonary disease

,

atrial fibrillation

,

obstructive lung diseases

,

urinary tract infections

,

,

,

bacterial infections

,

,

,

,

,

,

,

,

respiratory tract infections

,

,

,

,

type 2 diabetes mellitus

,

,

,

,

staphylococcal infections

,

liver cirrhosis

,

,

,

,

respiratory distress syndrome

,

,

,

ocular hypertension

,

open-angle glaucoma

,

infectious arthritis

,

,

respiratory sounds

,

tooth extraction

,

coronary artery disease

,

,

angina pectoris

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

diabetic nephropathies

,

kidney diseases

,

,

,

,

pyogenic liver abscess

,

gastrointestinal hemorrhage

,

esophageal and gastric varices

,

pituitary neoplasms

,

,

pituitary diseases

,

dental focal infection

,

focal infection

,

respiratory insufficiency

,

,

,

chronic bronchitis

,

airway obstruction

,

disease progression

,

essential tremor

,

,

heart septal defects

,

ventricular heart septal defects

,

cardiac surgical procedures

,

neonatal sepsis

,

,

,

,

venous thrombosis

,

pulmonary embolism

,

,

vascular diseases

,

bronchopulmonary dysplasia

,

,

,

,

,

postoperative cognitive complications

,

cognitive dysfunction

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

,

myocardial ischemia

,

,

,

premature birth

,

premature rupture fetal membranes

,

,

high-risk pregnancy

,

carpal tunnel syndrome

,

,

adrenocortical adenoma

,

cytokine release syndrome

,

viral pneumonia

,

,

,

erectile dysfunction

,

drug monitoring

,

,

bipolar disorder

,

polycystic ovary syndrome

,

peritonsillar abscess

,

spinal anesthesia

,

gestational trophoblastic disease

,

choriocarcinoma

,

trophoblastic neoplasms

,

invasive hydatidiform mole

,

,

protein-energy malnutrition

,

,

,

acute kidney injury

,

,

,

long qt syndrome

,

romano-ward syndrome

,

,

,

,

,

fallopian tube neoplasms

,

,

,

,

,

ventricular tachycardia

,

aortic dissection

,

thoracic surgical procedures

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

healthy volunteers/patients

,

renal insufficiency

,

chronic kidney failure

,

myeloid leukemia acute

,

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

,

acquired immunodeficiency syndrome

,

immunologic deficiency syndromes

,

psoriatic arthritis

,

myeloid leukemia

,

,

,

respiratory syncytial virus infections

,

precursor cell lymphoblastic leukemia-lymphoma

,

respiratory syncytial viruses

,

,

venous thrombosis

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

smoldering multiple myeloma

,

,

neoplasm metastasis

,

,

,

chronic hepatitis c

,

,

,

breast neoplasms

,

,

peripheral nervous system diseases

,

hematologic neoplasms

,

colorectal neoplasms

,

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

multiple myeloma

,

plasma cell neoplasms

,

,

non-small-cell lung carcinoma

,

,

,

,

communicable diseases

,

,

,

,

,

lymphoid leukemia

,

,

depressive disorder

,

ovarian neoplasms

,

,

juvenile arthritis

,

,

respiratory tract infections

,

,

major depressive disorder

,

treatment-resistant depressive disorder

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

ovarian epithelial carcinoma

,

b-cell chronic lymphocytic leukemia

,

respiratory insufficiency

,

rheumatic diseases

,

collagen diseases

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

,

psychotic disorders

,

bipolar disorder

,

psychotic affective disorders

,

,

mental disorders

,

human influenza

,

venous thromboembolism

,

thromboembolism

,

,

type 2 diabetes mellitus

,

,

diabetes mellitus

,

prostatic neoplasms

,

urogenital neoplasms

,

male genital diseases

,

male genital neoplasms

,

genital diseases

,

,

,

attention deficit disorder with hyperactivity

,

cognitive dysfunction

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

,

,

retinal diseases

,

,

ankle fractures

,

,

joint dislocations

,

fibula fractures

healthy volunteers/patients

root canal obturation

healthy volunteers/patients

,

,

chronic hepatitis c

,

,

,

,

communicable diseases

,

soft tissue infections

,

bacterial pneumonia

,

,

,

cystic fibrosis

,

pseudomonas aeruginosa

,

,

hiv seropositivity

,

renal insufficiency

,

,

urinary tract infections

,

communicable diseases

,

healthy volunteers/patients

,

,

,

acquired immunodeficiency syndrome

,

,

chronic hepatitis c

,

systemic lupus erythematosus

,

alzheimer disease

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