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Company ReportsEntasis Therapeutics

Entasis Therapeutics(ETTX)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Xacduro	Sulbactam, Durlobactam	2023-05-23	2033-2035	Respiratory tract infections , Urinary tract infections , Pneumococcal infections , Infectious pregnancy complications , Bacterial infections , Gonorrhea , Intraabdominal infections , Bacterial skin diseases , Escherichia coli infections , Soft tissue infections , Bacillary dysentery , Surgical wound infection , Staphylococcal infections , Bacterial endocarditis , Bacterial meningitis , Salmonella infections , Proteus infections , Acinetobacter infections , Listeriosis , Klebsiella infections , Meningococcal infections , Haemophilus infections , Human bites , Actinomycosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

bacterial pneumonia

,

,

,

communicable diseases

,

,

,

wound infection

,

,

abdominal abscess

,

,

renal insufficiency

,

healthy volunteers/patients

,

,

communicable diseases

,

urinary tract infections

,

,

acinetobacter infections

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

bacterial pneumonia

,

healthy volunteers/patients

,

bacterial infections

,

healthy volunteers/patients

,

,

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

communicable diseases

,

dental focal infection

,

focal infection

,

communicable diseases

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

bacterial pneumonia

,

,

acinetobacter infections

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

deficiency diseases

,

paraproteinemias

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

breast neoplasms

,

immune system diseases

,

hematologic neoplasms

,

type 2 diabetes mellitus

,

,

metabolic diseases

,

,

,

immunoglobulin g4-related disease

,

,

falciparum malaria

,

,

,

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

renal insufficiency

,

hematologic diseases

,

blood protein disorders

,

neoplasms by histologic type

,

prostatic neoplasms

,

circulating neoplastic cells

,

heart transplantation

,

non-small-cell lung carcinoma

,

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

,

aplastic anemia

,

multiple myeloma

,

plasma cell neoplasms

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

meningococcal infections

,

hemolytic anemia autoimmune

,

,

meningococcal meningitis

,

stomach neoplasms

,

,

kidney diseases

,

gaucher disease

,

smoldering multiple myeloma

,

,

chronic renal insufficiency

,

hyperphosphatemia

,

multiple sclerosis

,

,

homozygous familial hypercholesterolemia

,

,

,

healthy volunteers/patients

,

,

glycogen storage disease type ii

,

glycogen storage disease

,

atopic dermatitis

,

,

,

,

diabetes mellitus

,

,

glycogen storage disease type iii

,

non-hodgkin lymphoma

,

,

postmenopausal osteoporosis

,

lymphoproliferative disorders

healthy volunteers/patients

healthy volunteers/patients

,

pure red-cell aplasia

,

chronic kidney failure

,

,

kidney diseases

,

chronic renal insufficiency

,

type 2 diabetes mellitus

,

diabetes mellitus

,

acute coronary syndrome

,

,

renal insufficiency

,

pharmacokinetics

,

multiple myeloma

,

plasma cell neoplasms

,

cytomegalovirus infections

,

cytomegalovirus

pharmacokinetics

,

chronic kidney failure

,

renal insufficiency

,

cerebral ventriculitis

,

cerebrospinal fluid shunts

,

ventriculoperitoneal shunt

,

retinal diseases

,

aids-related complex

,

,

mandibular fractures

,

viral pneumonia

,

,

,

,

,

,

,

breast neoplasms

,

,

prostatic neoplasms

,

,

chlamydia infections

,

,

erectile dysfunction

,

bipolar disorder

,

,

ovarian epithelial carcinoma

,

male breast neoplasms

,

,

invasive hydatidiform mole

,

,

,

ulcerative colitis

,

inflammatory bowel diseases

,

,

subacute bacterial endocarditis

,

parkinson disease

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

psychotic disorders

,

mental disorders

,

fallopian tube neoplasms

,

,

synovial sarcoma

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors

,

primitive neuroectodermal tumors peripheral

,

alveolar rhabdomyosarcoma

,

,

embryonal rhabdomyosarcoma

,

neuroectodermal tumors

,

renal cell carcinoma

,

endometrial neoplasms

,

endometrioid carcinoma

,

,

follicular lymphoma

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

,

large-cell lymphoma anaplastic

,

burkitt lymphoma

,

brain neoplasms

,

,

,

,

,

salivary gland neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

oropharyngeal neoplasms

,

unknown primary neoplasms

,

squamous cell neoplasms

,

tongue neoplasms

,

laryngeal neoplasms

,

verrucous carcinoma

,

paranasal sinus neoplasms

,

laryngeal diseases

,

bile duct neoplasms

,

liver neoplasms

,

cholangiocarcinoma

,

gallbladder neoplasms

,

urinary bladder neoplasms

,

kidney neoplasms

,

urethral neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

,

pulmonary tuberculosis

,

out-of-hospital cardiac arrest

,

bacillary dysentery

,

tibial meniscus injuries

,

cartilage fractures

,

,

cardiovascular diseases

,

ischemic stroke

,

,

cerebrovascular disorders

,

central nervous system diseases

,

,

,

cephalosporin resistance

,

enterobacteriaceae infections

,

,

,

,

chronic hepatitis c

,

,

,

,

post-lyme disease syndrome

,

,

severe acute malnutrition

,

pseudomonas infections

,

,

bacterial skin diseases

,

kidney diseases

,

systemic inflammatory response syndrome

,

microbial drug resistance

,

bacterial drug resistance

,

methicillin-resistant staphylococcus aureus

,

esophageal achalasia

,

,

hepatocellular carcinoma

,

antibiotic prophylaxis

,

nervous system diseases

,

uterine cervicitis

,

,

,

environmental biomarkers

,

escherichia coli infections

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

hemopneumothorax

,

,

,

chronic renal insufficiency

,

congenital abnormalities

,

vesico-ureteral reflux

,

chronic obstructive pulmonary disease

,

disease progression

,

,

acquired immunodeficiency syndrome

,

child nutrition disorders

,

hidradenitis suppurativa

,

,

asymptomatic diseases

,

,

artificial respiration

,

intellectual disability

,

,

communicable diseases

,

,

healthy volunteers/patients

,

,

bacterial infections

,

urinary tract infections

,

critical illness

,

bacterial pneumonia

,

hypersensitivity

,

intraabdominal infections

,

,

,

,

ventilator-associated pneumonia

,

,

cystic fibrosis

,

,

,

healthcare-associated pneumonia

,

gram-negative bacterial infections

,

,

staphylococcal infections

,

,

,

,

surgical wound infection

,

soft tissue infections

,

,

,

,

community-acquired pneumonia

,

,

respiratory tract infections

,

febrile neutropenia

,

drug hypersensitivity

,

,

,

,

,

infectious arthritis

,

lyme neuroborreliosis

,

,

,

,

liver cirrhosis

,

wound infection

,

,

bacterial endocarditis

,

,

,

wounds and injuries

,

,

,

community-acquired infections

,

bacterial vaginosis

,

chronic bronchitis

,

,

bacterial meningitis

,

central nervous system infections

,

,

cross infection

,

hematologic neoplasms

,

staphylococcal skin infections

,

infectious skin diseases

,

,

,

,

pyogenic liver abscess

,

klebsiella infections

,

gastrointestinal hemorrhage

,

,

,

,

immediate hypersensitivity

,

drug-related side effects and adverse reactions

,

,

non-hodgkin lymphoma

,

premature birth

,

,

adaptive immunity

,

nephrolithiasis

,

,

diabetes mellitus

,

,

esophageal and gastric varices

,

pneumococcal pneumonia

,

abdominal abscess

,

acalculous cholecystitis

,

pregnancy complications

,

postpartum hemorrhage

,

pituitary neoplasms

,

,

pituitary diseases

,

pseudomonas aeruginosa

,

peritoneal dialysis

,

,

otitis media with effusion

,

,

,

neisseria gonorrhoeae

,

respiratory aspiration

,

aspiration pneumonia

,

,

substance-related disorders

,

intravenous substance abuse

,

pulmonary infarction

,

gastroenteritis

,

pulmonary fibrosis

,

,

,

premature rupture fetal membranes

,

,

high-risk pregnancy

,

multiple drug resistance

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

drug monitoring

,

acute kidney injury

,

,

newborn respiratory distress syndrome

,

blood coagulation disorders

,

hemostatic disorders

,

neurotoxicity syndromes

,

penicillin resistance

,

respiratory distress syndrome

,

,

streptococcal infections

,

replacement arthroplasty hip

,

,

,

coronavirus infections

,

,

,

,

,

mucocutaneous lymph node syndrome

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

hyperphosphatemia

,

,

,

sleep initiation and maintenance disorders

,

cardiac arrhythmias

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

,

,

,

disease susceptibility

,

,

propionibacterium acnes

,

aseptic meningitis

,

benign migratory glossitis

,

erythema chronicum migrans

,

,

,

depressive disorder

,

salmonella infections

,

hiv seropositivity

,

,

hemodiafiltration

,

continuous renal replacement therapy

,

gram-positive bacterial infections

,

,

digestive system fistula

,

retinal detachment

,

dissociative disorders

,

,

,

menstruation disturbances

,

,

protein-energy malnutrition

,

,

nut hypersensitivity

,

,

delayed hypersensitivity

,

streptococcus agalactiae

,

recreational drug use

,

postoperative complications

,

laboratory infection

,

acute lung injury

,

,

,

,

hip osteoarthritis

,

,

cardiogenic shock

,

acinetobacter baumannii

,

end stage liver disease

,

,

acute-on-chronic liver failure

,

conservative treatment

,

respiratory insufficiency

,

respiration disorders

renal insufficiency

,

,

urinary tract infections

,

communicable diseases

,

long qt syndrome

,

type 2 diabetes mellitus

,

,

,

diabetes mellitus

,

,

,

therapeutic equivalency

,

alzheimer disease

,

torsades de pointes

,

cystic fibrosis

,

,

,

coronary artery disease

,

myocardial ischemia

,

cardiovascular abnormalities

,

,

,

electrocardiography

,

drug interactions

,

,

,

,

,

,

psychotic disorders

,

renal cell carcinoma

,

cardiomyopathies

,

,

,

coronary disease

,

human influenza

,

erectile dysfunction

,

,

polycythemia vera

,

duchenne muscular dystrophy

,

muscular dystrophies

,

autoimmune diseases

,

orthostatic hypotension

,

migraine disorders

,

,

,

acute coronary syndrome

,

lice infestations

,

restless legs syndrome

,

major depressive disorder

,

depressive disorder

,

,

falciparum malaria

,

,

chronic hepatitis c

,

drug-related side effects and adverse reactions

,

postoperative pain

,

overactive urinary bladder

,

,

acinetobacter infections

,

,

systemic lupus erythematosus

,

pulmonary arterial hypertension

,

,

embryo transfer

,

,

premature obstetric labor

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

,

rheumatoid arthritis

,

,

,

respiratory aspiration

,

atrial fibrillation

,

atherosclerosis

,

human experimentation

,

,

,

,

non-alcoholic fatty liver disease

,

,

alcoholic fatty liver

,

smoking cessation

,

postpartum hemorrhage

,

,

respiratory syncytial virus infections

,

retinal vein occlusion

,

choroidal neovascularization

,

,

pathologic neovascularization

,

sickle cell anemia

,

,

kidney diseases

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

pharmacokinetics

,

parkinson disease

,

pharmacological phenomena

,

,

,

,

,

,

,

h1n1 subtype influenza a virus

,

tobacco use disorder

,

,

,

,

anorexia nervosa

,

graft vs host disease

,

,

muscle spasticity

,

spinal tuberculosis

,

,

,

bacterial pneumonia

,

acquired immunodeficiency syndrome

,

community-acquired infections

,

,

breast neoplasms

,

,

,

mycobacterium infections

,

,

,

extensively drug-resistant tuberculosis

,

,

bacterial skin diseases

,

multiple myeloma

,

,

,

abdominal abscess

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

plasma cell neoplasms

,

,

,

meningeal tuberculosis

,

,

phenylketonurias

,

mycobacterium tuberculosis

,

,

,

environmental biomarkers

,

,

,

infectious skin diseases

,

,

wound infection

,

triple negative breast neoplasms

,

aspiration pneumonia

,

,

,

,

,

ovarian neoplasms

,

,

germ cell and embryonal neoplasms

,

trophoblastic neoplasms

,

newborn infant diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

capsule opacification

,

phacoemulsification

,

,

nontuberculous mycobacterium infections

,

acute cholecystitis

,

,

acalculous cholecystitis

,

non-hodgkin lymphoma

,

hodgkin disease

,

,

,

acanthamoeba keratitis

,

,

hidradenitis suppurativa

,

,

latent tuberculosis

,

disease susceptibility

,

prosthesis-related infections

,

lymph node tuberculosis

,

healthy volunteers/patients

,

,

,

pulmonary tuberculosis

,

,

,

communicable diseases

,

multidrug-resistant tuberculosis

,

chronic obstructive pulmonary disease

,

bacterial infections

,

endophthalmitis

,

obstructive lung diseases

,

,

,

,

bacterial conjunctivitis

,

,

,

cataract extraction

,

,

,

chronic bronchitis

,

helicobacter infections

,

,

community-acquired pneumonia

,

,

intraabdominal infections

,

,

,

hypersensitivity

,

,

,

,

retinal detachment

,

contraception behavior

,

,

,

disease progression

,

pelvic infection

,

pelvic inflammatory disease

,

cardiovascular diseases

,

aggressive periodontitis

,

,

soft tissue infections

,

respiratory tract infections

,

corneal transplantation

,

intraocular pressure

,

,

,

insulin resistance

,

,

chronic periodontitis

,

maxillary sinusitis

,

penetrating eye injuries

,

microbial drug resistance

,

cardiac arrhythmias

,

bacterial endocarditis

,

,

,

pyogenic liver abscess

,

penetrating keratoplasty

,

,

,

patient preference

,

,

vision disorders

,

heart disease risk factors

,

,

,

intravitreal injections

,

,

metabolic syndrome

,

microvascular angina

,

bacterial eye infections

,

,

periodontal pocket

,

,

corneal injuries

,

pulmonary infarction

,

gastroenteritis

,

,

pathologic dilatation

,

,

macular degeneration

,

wounds and injuries

,

,

pneumococcal pneumonia

,

pneumococcal infections

,

urinary tract infections

,

aortic dissection

,

,

mycoplasma pneumonia

,

mycoplasma infections

,

pleuropneumonia

,

chemical and drug induced liver injury

,

,

venous thrombosis

,

respiratory tract diseases

,

respiration disorders

,

,

bronchial diseases

,

,

precancerous conditions

,

,

dissociative disorders

,

,

,

postoperative complications

,

laboratory infection

,

body weight changes

,

appetitive behavior

,

feeding behavior

,

,

meibomian gland dysfunction

,

pleural empyema

,

,

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