Sincalide
Kinevac, Sincalide (sincalide) is a protein pharmaceutical. Sincalide was first approved as Kinevac on 1982-01-01. It is known to target cholecystokinin receptor type A and gastrin/cholecystokinin type B receptor.
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Drug
Target
Variants
Financial
Trends
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YTD
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2Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Kinevac, Sincalide
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sincalide
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| KINEVAC | Bracco Diagnostics | N-017697 RX | 1982-01-01 | 1 products, RLD, RS |
| SINCALIDE | MAIA Biotechnology | N-210850 RX | 2022-11-22 | 1 products, RLD, RS |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
HCPCS
Code | Description |
|---|---|
| J2805 | Injection, sincalide, 5 micrograms |
Clinical
No data
Drug
General
| Drug common name | Sincalide |
| INN | sincalide |
| Description | SINCALIDE |
| Classification | Peptide |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(=O)(=O)O)cc1)NC(=O)[C@@H](N)CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
Identifiers
| PDB | — |
| CAS-ID | 25126-32-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1121 |
| ChEBI ID | — |
| PubChem CID | 32800 |
| DrugBank | DB09142 |
| UNII ID | M03GIQ7Z6P (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CCKAR
CCKAR
CCKBR
CCKBR
Organism
Homo sapiens
Gene name
CCKAR
Gene synonyms
CCKRA
NCBI Gene ID
Protein name
cholecystokinin receptor type A
Protein synonyms
CCK-A receptor, CCK-AR, CCK1-R, cholecystokinin type 1 receptor, cholecystokinin type-A receptor, Cholecystokinin-1 receptor
Uniprot ID
Mouse ortholog
Cckar (12425)
cholecystokinin receptor type A (Q9DBV6)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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