Simeticone
Simeticone is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Commercial
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Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| phazyme | C200263 | 2025-02-04 |
| phazyme ultimate | C200263 | 2024-08-14 |
Indications
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Clinical
Clinical Trials
103 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 8 | — | — | 1 | 1 | 10 |
| Colonoscopy | D003113 | — | — | — | — | 2 | 4 | 2 | 8 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | 1 | — | — | 3 | 2 | 6 |
| Capsule endoscopy | D053704 | — | — | — | — | — | 1 | 4 | 5 |
| Colic | D003085 | — | R10.83 | — | 2 | — | 1 | 2 | 5 |
| Diarrhea | D003967 | — | R19.7 | — | 1 | 1 | 2 | 1 | 5 |
| Colonic polyps | D003111 | — | K63.5 | — | — | 1 | 2 | 2 | 5 |
| Syndrome | D013577 | — | — | — | 1 | — | 2 | 2 | 5 |
| Intestinal diseases | D007410 | — | K63.9 | — | 1 | 1 | 2 | — | 4 |
| Adenoma | D000236 | — | — | — | — | — | 2 | 2 | 4 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gastrointestinal diseases | D005767 | — | — | — | 2 | 1 | — | 3 | 6 |
| Colorectal neoplasms | D015179 | — | — | — | — | 1 | — | 4 | 5 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | 1 | — | 2 | — | 1 | 4 |
| Stomach diseases | D013272 | — | — | — | 1 | 1 | — | 2 | 4 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 3 | 3 | — | — | 3 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | 3 | 3 | — | — | 3 |
| Vomiting | D014839 | — | R11.1 | — | — | 1 | — | 1 | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | 1 | — | 1 | — | — | 2 |
| Gastrointestinal hemorrhage | D006471 | — | K92.2 | 1 | — | 1 | — | — | 2 |
| Constipation | D003248 | — | K59.0 | — | 1 | 1 | — | — | 2 |
Show 11 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | — | 2 | — | — | 3 | 5 |
| Autism spectrum disorder | D000067877 | — | F84.0 | — | 1 | — | — | 1 | 2 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | — | — | — | 1 |
| Ovarian epithelial carcinoma | D000077216 | — | — | — | 1 | — | — | — | 1 |
| Pathologic complete response | D000095384 | — | — | — | 1 | — | — | — | 1 |
| Otitis media | D010033 | EFO_0004992 | H66.9 | — | 1 | — | — | — | 1 |
| Otitis | D010031 | — | — | — | 1 | — | — | — | 1 |
| Diabetes complications | D048909 | — | — | — | 1 | — | — | — | 1 |
| Macular edema | D008269 | — | — | — | 1 | — | — | — | 1 |
| Diabetic retinopathy | D003930 | EFO_0003770 | — | — | 1 | — | — | — | 1 |
Show 5 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Abdominal pain | D015746 | EFO_0003766 | R10.9 | 1 | — | — | — | 1 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | — | — | — | — | 2 |
| Traumatic brain injuries | D000070642 | — | S06 | 1 | — | — | — | — | 1 |
| Brain concussion | D001924 | — | S06.0 | 1 | — | — | — | — | 1 |
| Brain injuries | D001930 | — | S06.9 | 1 | — | — | — | — | 1 |
| Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | 1 | — | — | — | — | 1 |
| Traumatic stress disorders | D040921 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Mitral valve insufficiency | D008944 | — | — | — | — | — | — | 1 | 1 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | — | 1 | 1 |
| Peptic esophagitis | D004942 | EFO_1001095 | — | — | — | — | — | 1 | 1 |
| Cough | D003371 | — | R05 | — | — | — | — | 1 | 1 |
| Chronic cough | D000096822 | — | R05.3 | — | — | — | — | 1 | 1 |
| Rectal neoplasms | D012004 | — | — | — | — | — | — | 1 | 1 |
| Polyps | D011127 | EFO_0000662 | — | — | — | — | — | 1 | 1 |
| Gastroscopy | D005773 | — | — | — | — | — | — | 1 | 1 |
| Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 1 | 1 |
| Lactose intolerance | D007787 | — | E73 | — | — | — | — | 1 | 1 |
Show 10 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Simeticone |
| INN | — |
| Description | Simeticone (INN), also known as simethicone (USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.
|
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108741 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB09512 |
| UNII ID | — |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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101 adverse events reported
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