Sasanlimab
Sasanlimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
27 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 13 | 3 | 1 | — | — | 14 |
| Urinary bladder neoplasms | D001749 | — | C67 | 4 | 1 | 1 | — | — | 6 |
| Non-muscle invasive bladder neoplasms | D000093284 | — | — | 3 | — | 1 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 8 | 2 | — | — | — | 9 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 6 | 2 | — | — | — | 8 |
| Lung neoplasms | D008175 | — | C34.90 | 4 | 1 | — | — | — | 4 |
| Transitional cell carcinoma | D002295 | — | — | 3 | 1 | — | — | — | 4 |
| Urologic neoplasms | D014571 | — | C64-C68 | 2 | 1 | — | — | — | 3 |
| Carcinoma | D002277 | — | C80.0 | 1 | 2 | — | — | — | 3 |
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 1 | 2 | — | — | — | 3 |
| Adenocarcinoma | D000230 | — | — | 1 | 1 | — | — | — | 2 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | 1 | — | — | — | 1 |
| Urogenital neoplasms | D014565 | EFO_0003863 | D07 | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | — | — | 10 | — | — | — | — | 10 |
| Colorectal neoplasms | D015179 | — | — | 8 | — | — | — | — | 8 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 6 | — | — | — | — | 6 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 4 | — | — | — | — | 4 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 4 | — | — | — | — | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 4 | — | — | — | — | 4 |
| Head and neck neoplasms | D006258 | — | — | 4 | — | — | — | — | 4 |
| Esophageal neoplasms | D004938 | — | C15 | 3 | — | — | — | — | 3 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 2 | — | — | — | — | 2 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 2 | — | — | — | — | 2 |
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Sasanlimab |
| INN | sasanlimab |
| Description | Sasanlimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | >6XKR:H|Sasanlimab Fab Heavy chain
QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYWINWVRQAPGQGLEWMGNIYPGSSLTNYNEKFKNRVTMTRDTSTSTVY
MELSSLRSEDTAVYYCARLSTGTFAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCAAAHHHHHHHH
>6XKR:L|Sasanlimab Fab Light chain
DIVMTQSPDSLAVSLGERATINCKSSQSLWDSGNQKNFLTWYQQKPGQPPKLLIYWTSYRESGVPDRFSGSGSGTDFTLT
ISSLQAEDVAVYYCQNDYFYPHTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
Identifiers
| PDB | 6XKR |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4298191 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | LZZ0IC2EWP (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 121 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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42 adverse events reported
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