Selicrelumab
Selicrelumab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
126 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Blood pressure | D001794 | EFO_0004325 | — | — | — | — | 1 | — | 1 |
| Platelet activation | D015539 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syndrome | D013577 | — | — | 1 | 3 | 1 | — | — | 4 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | 3 | 1 | — | 1 | 4 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | 3 | 1 | — | 1 | 4 |
| Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | — | 2 | 1 | — | — | 3 |
| Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | — | — | 1 | — | 1 | 2 |
| Thrombocytopenia | D013921 | HP_0001873 | D69.6 | 1 | 1 | 1 | — | — | 2 |
| Thrombocytopenic purpura | D011696 | — | — | — | — | 1 | — | 1 | 2 |
| Purpura | D011693 | HP_0000979 | D69.2 | — | — | 1 | — | 1 | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 20 | 3 | — | — | — | 21 |
| Melanoma | D008545 | — | — | 14 | 9 | — | — | — | 18 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 12 | 3 | — | — | — | 12 |
| Carcinoma | D002277 | — | C80.0 | 10 | 4 | — | — | — | 12 |
| Lymphoma | D008223 | — | C85.9 | 9 | 3 | — | — | — | 11 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 8 | 3 | — | — | — | 10 |
| Adenocarcinoma | D000230 | — | — | 6 | 6 | — | — | — | 8 |
| Non-small-cell lung carcinoma | D002289 | — | — | 7 | 3 | — | — | — | 8 |
| Leukemia | D007938 | — | C95 | 8 | 1 | — | — | — | 8 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 7 | 1 | — | — | — | 7 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| B-cell lymphoma | D016393 | — | — | 5 | — | — | — | — | 5 |
| Multiple myeloma | D009101 | — | C90.0 | 4 | — | — | — | — | 4 |
| Plasma cell neoplasms | D054219 | — | — | 4 | — | — | — | — | 4 |
| Glandular and epithelial neoplasms | D009375 | — | — | 4 | — | — | — | — | 4 |
| Follicular lymphoma | D008224 | — | C82 | 3 | — | — | — | — | 3 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 3 | — | — | — | — | 3 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | — | — | — | — | 2 |
| Merkel cell carcinoma | D015266 | EFO_1001471 | C4A | 2 | — | — | — | — | 2 |
| Glioma | D005910 | EFO_0000520 | — | 2 | — | — | — | — | 2 |
| Myoepithelioma | D009208 | — | — | 2 | — | — | — | — | 2 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Primary immunodeficiency diseases | D000081207 | — | — | — | — | — | — | 2 | 2 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | — | — | 1 | 1 |
| Humoral immunity | D056724 | — | — | — | — | — | — | 1 | 1 |
| Coronary disease | D003327 | — | — | — | — | — | — | 1 | 1 |
| Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | — | — | 1 | 1 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | — | — | 1 | 1 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | — | 1 | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
| Atherosclerotic plaque | D058226 | HP_0031678 | I70 | — | — | — | — | 1 | 1 |
| Septic shock | D012772 | — | A48.3 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Selicrelumab |
| INN | selicrelumab |
| Description | CP-870893 (mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109477 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 0O39RGI33V (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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79 adverse events reported
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