Rintatolimod
Rintatolimod is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
27 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fatigue | D005221 | — | R53.83 | — | — | 1 | — | 1 | 2 |
| Chronic fatigue syndrome | D015673 | EFO_0004540 | G93.31 | — | — | 1 | — | 1 | 2 |
| Syndrome | D013577 | — | — | — | — | 1 | — | 1 | 2 |
| Myalgia | D063806 | — | M79.1 | — | — | 1 | — | — | 1 |
| Encephalomyelitis | D004679 | EFO_0001423 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 2 | — | — | 2 | 6 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 4 | 2 | — | — | — | 4 |
| Colorectal neoplasms | D015179 | — | — | 1 | 4 | — | — | — | 4 |
| Adenocarcinoma | D000230 | — | — | 1 | 3 | — | — | — | 3 |
| Triple negative breast neoplasms | D064726 | — | — | 3 | 1 | — | — | — | 3 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 3 | — | — | — | 3 |
| Hiv seropositivity | D006679 | — | — | 1 | 2 | — | — | — | 3 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 2 | 2 | — | — | — | 2 |
| Peritoneal neoplasms | D010534 | — | — | 2 | 2 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast carcinoma in situ | D000071960 | — | D05 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | — | — | — | 1 | 1 |
| Aids-related complex | D000386 | EFO_0007137 | B20 | — | — | — | — | 1 | 1 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Rintatolimod |
| INN | rintatolimod |
| Description | Rintatolimod, sold under the tradename Ampligen, is a medication intended for treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). There is some evidence it may improve some ME/CFS symptoms.
|
| Classification | Oligonucleotide |
| Drug class | immunomodulators: immunomodulators, toll-like receptor agonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 38640-92-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107862 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 94325AJ25N (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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