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Drug ReportsRilotumumab
Rilotumumab
Rilotumumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against hepatocyte growth factor.
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Financial
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
17 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Stomach neoplasmsD013274EFO_0003897C16222——5
CarcinomaD002277—C80.0—31—14
Lung neoplasmsD008175HP_0100526C34.90131—14
AdenocarcinomaD000230——121——3
Squamous cell carcinomaD002294———11—12
Squamous cell neoplasmsD018307———11—12
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369—C8033———4
GliomaD005910EFO_0000520——2———2
Esophageal neoplasmsD004938—C1512———2
RecurrenceD012008——11———2
GlioblastomaD005909EFO_0000515——1———1
GliosarcomaD018316———1———1
Non-small-cell lung carcinomaD002289——11———1
Colorectal neoplasmsD015179——11———1
Gastrointestinal neoplasmsD005770—C26.911———1
Colonic neoplasmsD003110—C1811———1
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938—C951————1
Precursor cell lymphoblastic leukemia-lymphomaD054198——1————1
Acute diseaseD000208——1————1
Philadelphia chromosomeD010677——1————1
Lymphoid leukemiaD007945—C911————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRilotumumab
INNrilotumumab
Description
Rilotumumab (human mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL1743063
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID51WEW898IJ (ChemIDplus, GSRS)
Target
Agency Approved
HGF
HGF
Organism
Homo sapiens
Gene name
HGF
Gene synonyms
HPTA
NCBI Gene ID
Protein name
hepatocyte growth factor
Protein synonyms
fibroblast-derived tumor cytotoxic factor, hepatocyte growth factor (hepapoietin A; scatter factor), Hepatopoietin-A, lung fibroblast-derived mitogen, Scatter factor, SF
Uniprot ID
Mouse ortholog
Hgf (15234)
hepatocyte growth factor (Q6LBE6)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 949 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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52 adverse events reported
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