Riboflavin
Infuvite, M.v.i, Vitaped (riboflavin) is a small molecule pharmaceutical. Riboflavin was first approved as M.v.i.-12 adult on 1985-08-08. It is used to treat riboflavin deficiency in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| nutritional and metabolic diseases | D009750 |
Trade Name
FDA
EMA
Epioxa hd/epioxa, Photrexa viscous in dextran
CombinationsInfuvite (discontinued: Berocca pn, M.v.c. 9+, M.v.i., M.v.i. lyophilized, Mvc, Vitaped)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ascorbic acid
+
Biotin
+
Cholecalciferol
+
Cyanocobalamin
+
Dexpanthenol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Tocopherol acetate
+
Vitamin a
+
Vitamin k
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pantothenic acid
+
Phytonadione
+
Pyridoxine
+
Riboflavin
+
Thiamine
+
Vitamin a palmitate
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin 5'-phosphate sodium
+
Thiamine
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Riboflavin 5'-phosphate
Alpha-tocopherol acetate
+
Ascorbic acid
+
Biotin
+
Cholecalciferol
+
Cyanocobalamin
+
Dexpanthenol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin k
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 25 person ansi | OTC monograph final | 2010-06-07 |
| 50 person ansi | OTC monograph final | 2010-06-07 |
| adult infuvite multiple vitamins | New Drug Application | 2025-08-18 |
| arc first aid emergency preparedness contains 167 pieces | OTC monograph final | 2010-06-07 |
| aronamin gold | unapproved drug other | 2018-12-12 |
| bacmin | unapproved drug other | 2014-05-02 |
| bal-care dha | unapproved drug other | 2012-05-01 |
| bal-care dha essential | unapproved drug other | 2012-05-01 |
| bio no brain care (helps improve brain blood flow and body temperature, fermented garlic powder) | unapproved drug other | 2025-03-14 |
| bio no more yeast infection (helps improve vaginal yeast infection, fermented cabbage powder) | unapproved drug other | 2025-03-14 |
Show 153 more
Indications
FDA
EMA
Show 26 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A11: Vitamins
— A11H: Other plain vitamin preparations in atc
— A11HA: Other plain vitamin preparations in atc
— A11HA04: Riboflavin (vit b2)
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01X: Other ophthalmologicals in atc
— S01XA: Other ophthalmologicals in atc
— S01XA26: Riboflavin
HCPCS
Code | Description |
|---|---|
| J2787 | Riboflavin 5'-phosphate, ophthalmic solution, up to 3 ml |
Clinical
Clinical Trials
1199 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Keratoconus | D007640 | EFO_0004223 | H18.6 | 10 | 23 | 34 | 3 | 47 | 105 |
| Anemia | D000740 | EFO_0004272 | D64.9 | 1 | 2 | 6 | 4 | 29 | 42 |
| Covid-19 | D000086382 | — | U07.1 | 2 | 8 | 13 | 2 | 5 | 28 |
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | 3 | 1 | — | 3 | 21 | 28 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 3 | 2 | 2 | 19 | 26 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 6 | 4 | 1 | 16 | 24 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 1 | 3 | 3 | 15 | 22 |
| Infections | D007239 | EFO_0000544 | — | 1 | 1 | 6 | 1 | 13 | 21 |
| Neoplasms | D009369 | — | C80 | 8 | 4 | 1 | 2 | 8 | 20 |
| Corneal diseases | D003316 | — | H18.9 | — | 3 | 12 | 1 | 6 | 20 |
Show 110 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | 1 | 7 | — | 24 | 32 |
| Non-small-cell lung carcinoma | D002289 | — | — | 11 | 17 | 9 | — | 1 | 30 |
| Pathologic dilatation | D004108 | — | — | 2 | 7 | 19 | — | 6 | 30 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | 2 | — | 1 | — | 18 | 21 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 2 | 7 | 12 | — | 2 | 20 |
| Syndrome | D013577 | — | — | 3 | 5 | 2 | — | 11 | 18 |
| Keratitis | D007634 | — | H16 | 2 | 3 | 6 | — | 8 | 17 |
| Lung neoplasms | D008175 | — | C34.90 | 4 | 9 | 4 | — | 2 | 15 |
| Communicable diseases | D003141 | — | — | — | — | 5 | — | 10 | 15 |
| Colorectal neoplasms | D015179 | — | — | 4 | 6 | 1 | — | 3 | 12 |
Show 158 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 10 | 3 | — | — | 27 | 39 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 6 | 6 | — | — | 4 | 14 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 4 | — | — | 2 | 7 |
| Multiple myeloma | D009101 | — | C90.0 | 4 | 3 | — | — | — | 6 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 4 | 2 | — | — | 1 | 6 |
| Cocaine-related disorders | D019970 | — | F14 | — | 6 | — | — | — | 6 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 2 | — | — | 2 | 5 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 1 | — | — | 4 | 5 |
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | 1 | 1 | — | — | 3 | 5 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 2 | 1 | — | — | 3 | 5 |
Show 150 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Constipation | D003248 | — | K59.0 | 1 | — | — | — | 4 | 5 |
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | 1 | — | — | — | 4 | 5 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | 1 | — | — | — | 3 | 4 |
| T-cell lymphoma cutaneous | D016410 | — | C84.A | 3 | — | — | — | — | 3 |
| Pharmacokinetics | D010599 | — | — | 2 | — | — | — | 1 | 3 |
| Actinic keratosis | D055623 | — | L57.0 | 1 | — | — | — | 2 | 3 |
| Sezary syndrome | D012751 | — | C84.1 | 2 | — | — | — | — | 2 |
| Mycosis fungoides | D009182 | — | C84.0 | 2 | — | — | — | — | 2 |
| Nutritional status | D009752 | — | — | 1 | — | — | — | 1 | 2 |
| Biological availability | D001682 | — | — | 1 | — | — | — | 1 | 2 |
Show 44 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aging | D000375 | GO_0007568 | R41.81 | — | — | — | — | 8 | 8 |
| Weight loss | D015431 | — | — | — | — | — | — | 6 | 6 |
| Glaucoma | D005901 | EFO_0000516 | H40 | — | — | — | — | 6 | 6 |
| Dietary supplements | D019587 | — | — | — | — | — | — | 4 | 4 |
| Frailty | D000073496 | — | R53.1 | — | — | — | — | 4 | 4 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | — | — | 4 | 4 |
| Blood pressure | D001794 | EFO_0004325 | — | — | — | — | — | 4 | 4 |
| Folic acid deficiency | D005494 | EFO_0001070 | E53.8 | — | — | — | — | 4 | 4 |
| Protein-energy malnutrition | D011502 | EFO_0009563 | E41 | — | — | — | — | 4 | 4 |
| Gestational diabetes | D016640 | — | O24.4 | — | — | — | — | 4 | 4 |
Show 268 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Riboflavin |
| INN | riboflavin |
| Description | Riboflavin is d-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. It has a role as a photosensitizing agent, a food colouring, an Escherichia coli metabolite, a mouse metabolite, a cofactor, a plant metabolite, a human urinary metabolite, an anti-inflammatory agent, a fundamental metabolite and an antioxidant. It is a vitamin B2 and a flavin. It is a conjugate acid of a riboflavin(1-). |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C[C@H](O)[C@H](O)[C@H](O)CO)c2cc1C |
Identifiers
| PDB | — |
| CAS-ID | 83-88-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1534 |
| ChEBI ID | 17015 |
| PubChem CID | 493570 |
| DrugBank | DB00140 |
| UNII ID | TLM2976OFR (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Riboflavin
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 60,566 documents
View more details
Safety
Black-box Warning
Black-box warning for: Citranatal 90 dha, Citranatal assure, Citranatal dha, Citranatal essence, Citranatal rx, Healthy mamabe well rounded, Marnatal f, Moms choice rx, Natafort, Nestabs, Nestabs dha, O-cal prenatal vitamin, Pnv prenatal plus multivitamin, Pnv prenatal vitamin, Pnv-select, Pr natal 400, Pr natal 400 ec, Pr natal 430, Pr natal 430 ec, Pre-tabs dha, Prenata, Prenatal plus multivitamin plus dha minicaps, Prenate elite, Select ob, Select-ob plus dha, Tristart dha, Vitafol, Vitafol fe plus, Vitafol ob, Vitafol-ob plus dha
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
2,820 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use