Reproxalap
Reproxalap is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Commercial
No data
Clinical
Clinical Trials
30 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dry eye syndromes | D015352 | — | H04.12 | — | 7 | 7 | — | — | 13 |
| Keratoconjunctivitis sicca | D007638 | EFO_1000906 | — | — | 7 | 6 | — | — | 12 |
| Eye diseases | D005128 | EFO_0003966 | H44 | — | 6 | 6 | — | — | 11 |
| Conjunctivitis | D003231 | — | H10 | 2 | 4 | 3 | — | — | 7 |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | 2 | 4 | 3 | — | — | 7 |
| Syndrome | D013577 | — | — | — | 2 | 1 | — | — | 3 |
| Uveitis | D014605 | EFO_1001231 | H20.9 | — | 1 | 1 | — | — | 2 |
| Anterior uveitis | D014606 | EFO_1000811 | — | — | 1 | 1 | — | — | 2 |
| Iridocyclitis | D015863 | — | H20 | — | 1 | 1 | — | — | 2 |
| Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | — | 1 | 1 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | 1 | — | — | — | 1 |
| Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | — | 1 | — | — | — | 1 |
| Ichthyosis | D007057 | — | E50.8 | — | 1 | — | — | — | 1 |
| Alopecia areata | D000506 | EFO_0004192 | L63 | 1 | 1 | — | — | — | 1 |
| Alopecia | D000505 | — | L64 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Respiratory syncytial virus infections | D018357 | EFO_1001413 | — | 2 | — | — | — | — | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Adrenoleukodystrophy | D000326 | Orphanet_43 | E71.52 | — | — | — | — | 1 | 1 |
| Neurosyphilis | D009494 | EFO_0007339 | A50.40 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Reproxalap |
| INN | reproxalap |
| Description | Reproxalap is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | aldehyde traps |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(O)c1nc2ccc(Cl)cc2cc1N |
Identifiers
| PDB | — |
| CAS-ID | 916056-79-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297210 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | F0GIZ22IJH (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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