Remetinostat
Remetinostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 10% methyl salicylate pain relief patch | C200263 | 2024-06-27 |
| 1st medxpatch | C200263 | 2024-10-31 |
| 365 whole foods market anticavity/antigingivitis mouthwash | OTC monograph not final | 2022-05-12 |
| 701 dieda zhengtong yaogao medicated | OTC monograph not final | 2019-11-13 |
| 701 dieda zhengtong yaogao medicated plaster | OTC monograph not final | 2014-06-26 |
| advanced antiseptic citrus | C200263 | 2025-02-20 |
| advanced citrus antiseptic | C200263 | 2025-01-10 |
| advil targeted relief | C200263 | 2024-02-08 |
| ageless pain relief | C200263 | 2023-12-12 |
| air sinsin pas | OTC monograph final | 2011-06-06 |
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Clinical
Clinical Trials
668 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 15 | 19 | 8 | 1 | 5 | 42 |
| Actinic keratosis | D055623 | — | L57.0 | 1 | 4 | 12 | 7 | 13 | 35 |
| Keratosis | D007642 | — | — | 1 | 4 | 12 | 7 | 13 | 35 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | 6 | 8 | 1 | 2 | 10 | 26 |
| Depression | D003863 | — | F33.9 | 6 | 10 | 1 | 2 | 7 | 25 |
| Syndrome | D013577 | — | — | 5 | 13 | 5 | 2 | 5 | 23 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 6 | 6 | 1 | 2 | 8 | 22 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 3 | 6 | 1 | 6 | 2 | 18 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 3 | 7 | 1 | 4 | 2 | 17 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 3 | 9 | 4 | 1 | — | 17 |
Show 94 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | — | C61 | 5 | 17 | 6 | — | — | 24 |
| Adenocarcinoma | D000230 | — | — | 7 | 15 | 5 | — | — | 20 |
| Lymphoma | D008223 | — | C85.9 | 8 | 12 | 2 | — | — | 19 |
| Recurrence | D012008 | — | — | 8 | 10 | 2 | — | — | 18 |
| Leukemia | D007938 | — | C95 | 9 | 7 | 1 | — | — | 14 |
| Basal cell neoplasms | D018295 | — | — | 1 | 3 | 6 | — | 3 | 11 |
| Squamous cell carcinoma | D002294 | — | — | 5 | 6 | 1 | — | 1 | 10 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 8 | 3 | 1 | — | — | 10 |
| Myeloid leukemia | D007951 | — | C92 | 8 | 3 | 1 | — | — | 10 |
| Glioblastoma | D005909 | EFO_0000515 | — | 8 | 1 | 1 | — | 1 | 10 |
Show 63 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 21 | 3 | — | — | 9 | 33 |
| Neoplasms | D009369 | — | C80 | 17 | 14 | — | — | 2 | 29 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 14 | 11 | — | — | 2 | 18 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 7 | 8 | — | — | 1 | 12 |
| Lung neoplasms | D008175 | — | C34.90 | 6 | 4 | — | — | 1 | 9 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 4 | 4 | — | — | 1 | 8 |
| Fibrosis | D005355 | — | — | — | 2 | — | — | 6 | 8 |
| Myelodysplastic syndromes | D009190 | — | D46 | 4 | 5 | — | — | — | 7 |
| Multiple myeloma | D009101 | — | C90.0 | 5 | 2 | — | — | — | 7 |
| Glioma | D005910 | EFO_0000520 | — | 5 | 3 | — | — | — | 7 |
Show 212 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Shoulder pain | D020069 | — | M25.51 | 2 | — | — | — | 2 | 4 |
| Bursitis | D002062 | EFO_1000941 | M71.9 | 1 | — | — | — | 2 | 3 |
| Heart disease risk factors | D000082742 | — | — | 3 | — | — | — | — | 3 |
| Vasoconstriction | D014661 | — | — | 3 | — | — | — | — | 3 |
| Disease | D004194 | EFO_0000408 | R69 | 3 | — | — | — | — | 3 |
| Contraception | D003267 | — | — | 2 | — | — | — | — | 2 |
| Serous cystadenocarcinoma | D018284 | — | — | 2 | — | — | — | — | 2 |
| Hepatic insufficiency | D048550 | — | — | 2 | — | — | — | — | 2 |
| Abdominal pain | D015746 | EFO_0003766 | R10.9 | 1 | — | — | — | 1 | 2 |
| Migraine disorders | D008881 | EFO_0003821 | G43 | 1 | — | — | — | 1 | 2 |
Show 57 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | — | — | — | 4 | 4 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | — | 4 | 4 |
| Trigger finger disorder | D052582 | — | M65.3 | — | — | — | — | 3 | 3 |
| Overweight | D050177 | — | E66.3 | — | — | — | — | 3 | 3 |
| Dystocia | D004420 | EFO_1000911 | O66.9 | — | — | — | — | 2 | 2 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | — | — | — | — | 2 | 2 |
| Minimally invasive surgical procedures | D019060 | — | — | — | — | — | — | 2 | 2 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | — | — | 2 | 2 |
| Stomatitis | D013280 | EFO_1001904 | K12.1 | — | — | — | — | 2 | 2 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 2 | 2 |
Show 120 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Remetinostat |
| INN | remetinostat |
| Description | Remetinostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors: histone deacetylase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COC(=O)c1ccc(OC(=O)CCCCCCC(=O)NO)cc1 |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3707219 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 37NT056AT4 (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
Black-box Warning
Black-box warning for: Aptensio xr, Concerta, Cotempla xr-odt, Covaryx, Covaryx covaryx, Daytrana, Diclovix m, Dyural 40 kit, Dyural 80 kit, Dyural 80-lm, Dyural lm kit, Eemt, Eemt eemt, Esterified estrogens and methyltestosterone, Esterified estrogens and methyltestosterone full strength esterified estrogens and methyltestosterone half strength, Estratest f.s., Estratest f.s. estratest h.s., Estratest fs estratest hs, Fenovar, Healthy mamabe well rounded, Hycodan, Hydrocodone bitartrate and homatropine methylbromide, Hydromet, Jornay pm, Metadate cd, Metadate er, Methylene blue, Methylene blue inj, Methylin, Methylphenidate, Methylphenidate hydrochloride, Methylphenidate hydrochloride (la), Methylphenidate hydrochloride extended release, Methylphenidate transdermal system, Perseris, Physicians ez use m-pred, Prenate elite, Prenate essential, Provayblue, Quillichew er, Quillivant, Relexxii, Ritalin, Varophen
Adverse Events
Top Adverse Reactions
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227,736 adverse events reported
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