Therapeutic Area | MeSH |
---|---|
musculoskeletal diseases | D009140 |
nutritional and metabolic diseases | D009750 |
Brand Name | Status | Last Update |
---|---|---|
evista | New Drug Application | 2024-10-18 |
raloxifene hydrochloride | ANDA | 2024-10-31 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
postmenopausal osteoporosis | EFO_0003854 | D015663 | — |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Osteoporosis | D010024 | EFO_0003882 | M81.0 | — | — | 3 | 7 | 1 | 11 |
Postmenopausal osteoporosis | D015663 | EFO_0003854 | — | — | — | 3 | 5 | — | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | 2 | — | — | 2 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hot flashes | D019584 | — | — | — | 1 | — | — | — | 1 |
Drug common name | Raloxifene |
INN | raloxifene |
Description | Raloxifene is a member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogens at positions 2, 3, and 6 have been replaced by p-hydroxyphenyl, p-[2-(piperidin-1-yl)ethoxy]benzoyl, and hydroxy groups, respectively. It has a role as a bone density conservation agent, an estrogen receptor modulator and an estrogen antagonist. It is a member of phenols, an aromatic ketone, a member of 1-benzothiophenes and a N-oxyethylpiperidine. It is a conjugate base of a raloxifene(1+). |
Classification | Small molecule |
Drug class | antiestrogens of the clomifene and tamoxifen groups |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 |
PDB | — |
CAS-ID | 84449-90-1 |
RxCUI | — |
ChEMBL ID | CHEMBL81 |
ChEBI ID | 8772 |
PubChem CID | 5035 |
DrugBank | DB00481 |
UNII ID | YX9162EO3I (ChemIDplus, GSRS) |