Phenylpropanolamine
Capsule, Codamine, Triaminic (phenylpropanolamine) is a small molecule pharmaceutical. Phenylpropanolamine was first approved as Triaminic-12 on 1982-01-01. It is used to treat common cold, obesity, rhinitis, and urinary incontinence in the USA.
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Respiratory tract infections | D012141 | — | J06.9 | — | — | 1 | 1 | — | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | 1 | — | 2 |
| Common cold | D003139 | EFO_0007214 | J00 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | — | 1 | — | — | 1 |
| Communicable diseases | D003141 | — | — | — | — | 1 | — | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Phenylpropanolamine |
| INN | phenylpropanolamine |
| Description | (-)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1R,2S-stereoisomer). It is a plant alkaloid. It has a role as a plant metabolite. It is a member of amphetamines and a phenethylamine alkaloid. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(N)C(O)c1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 14838-15-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL61006 |
| ChEBI ID | — |
| PubChem CID | 10297 |
| DrugBank | DB00397 |
| UNII ID | 33RU150WUN (ChemIDplus, GSRS) |
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Estimated US medical usage
Phenylpropanolamine
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Codeine
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Brompheniramine
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Brompheniramine
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Phenylpropanolamine
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Chlorpheniramine
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Phenylpropanolamine
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Clemastine
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Phenylpropanolamine
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Guaifenesin
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Codeine
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Phenylpropanolamine
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Dextromethorphan
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Guaifenesin
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Phenylpropanolamine
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Hydrocodone
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Phenylpropanolamine
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Safety
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801 adverse events reported
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