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Drug ReportsPhenylpropanolamine
Phenylpropanolamine
Capsule, Codamine, Triaminic (phenylpropanolamine) is a small molecule pharmaceutical. Phenylpropanolamine was first approved as Triaminic-12 on 1982-01-01. It is used to treat common cold, obesity, rhinitis, and urinary incontinence in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
urogenital diseasesD000091642
nutritional and metabolic diseasesD009750
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
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Drug Products
FDA
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Chlorpheniramine maleate
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Phenylpropanolamine hydrochloride
Tradename
Company
Number
Date
Products
TRIAMINIC-12NovartisN-018115 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Agency Specific
FDA
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Patent Expiration
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ATC Codes
R: Respiratory system drugs
R01: Nasal preparations
R01B: Nasal decongestants for systemic use
R01BA: Sympathomimetics
R01BA01: Phenylpropanolamine
R01BA51: Phenylpropanolamine, combinations
HCPCS
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Clinical
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Drug
General
Drug common namePhenylpropanolamine
INNphenylpropanolamine
Description
(-)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1R,2S-stereoisomer). It is a plant alkaloid. It has a role as a plant metabolite. It is a member of amphetamines and a phenethylamine alkaloid.
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(N)C(O)c1ccccc1
Identifiers
PDB
CAS-ID14838-15-4
RxCUI
ChEMBL IDCHEMBL61006
ChEBI ID
PubChem CID10297
DrugBankDB00397
UNII ID33RU150WUN (ChemIDplus, GSRS)
Target
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Variants
No data
Financial
Revenue by drug
$
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Estimated US medical usage
Phenylpropanolamine
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Codeine
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Brompheniramine
Total medical expenditures per year (USD, in millions)
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Phenylpropanolamine
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Brompheniramine
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Phenylpropanolamine
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Chlorpheniramine
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Phenylpropanolamine
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Clemastine
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Phenylpropanolamine
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Guaifenesin
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Codeine
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Phenylpropanolamine
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Dextromethorphan
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Phenylpropanolamine
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Guaifenesin
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Phenylpropanolamine
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Hydrocodone
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Phenylpropanolamine
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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