Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TRIAVIL 2-25 | New River Pharmaceuticals | N-014715 DISCN | 1982-01-01 | 1 products |
TRIAVIL 4-10 | New River Pharmaceuticals | N-014715 DISCN | 1982-01-01 | 1 products |
TRIAVIL 2-10 | New River Pharmaceuticals | N-014715 DISCN | 1982-01-01 | 1 products |
TRIAVIL 4-25 | New River Pharmaceuticals | N-014715 DISCN | 1982-01-01 | 1 products |
TRIAVIL 4-50 | New River Pharmaceuticals | N-014715 DISCN | 1982-01-01 | 1 products |
ETRAFON-A | Merck & Co | N-014713 DISCN | 1982-01-01 | 1 products |
ETRAFON 2-25 | Merck & Co | N-014713 DISCN | 1982-01-01 | 1 products |
ETRAFON-FORTE | Merck & Co | N-014713 DISCN | 1982-01-01 | 1 products |
ETRAFON 2-10 | Merck & Co | N-014713 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TRILAFON | Merck & Co | N-010775 DISCN | 1982-01-01 | 4 products, RLD |
TRILAFON | Merck & Co | N-011213 DISCN | 1982-01-01 | 1 products |
TRILAFON | Merck & Co | N-011294 DISCN | 1982-01-01 | 1 products |
TRILAFON | Merck & Co | N-011361 DISCN | 1982-01-01 | 1 products |
TRILAFON | Merck & Co | N-011557 DISCN | 1982-01-01 | 1 products |
Brand Name | Status | Last Update |
---|---|---|
perphenazine | ANDA | 2025-06-05 |
perphenazine and amitriptyline hydrochloride | ANDA | 2025-03-15 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Schizophrenia | D012559 | EFO_0000692 | F20 | — | 2 | 3 | 7 | 6 | 18 |
Psychotic disorders | D011618 | — | F20.81 | — | 1 | 2 | 3 | 2 | 8 |
Weight gain | D015430 | — | — | 1 | — | — | 1 | — | 2 |
Schizophrenia spectrum and other psychotic disorders | D019967 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Dementia | D003704 | EFO_0003862 | F03 | — | — | 2 | — | — | 2 |
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | 2 | — | — | 2 |
Vomiting | D014839 | — | R11.1 | — | — | 1 | — | — | 1 |
Nausea | D009325 | — | R11.0 | — | — | 1 | — | — | 1 |
Psychophysiologic disorders | D011602 | — | F45.9 | — | — | 1 | — | — | 1 |
Depression | D003863 | — | F33.9 | — | — | 1 | — | — | 1 |
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | — | 1 | — | — | 1 |
Somatoform disorders | D013001 | — | F45 | — | — | 1 | — | — | 1 |
Disease progression | D018450 | — | — | — | — | 1 | — | — | 1 |
Vascular dementia | D015140 | — | F01 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | 1 | — | — | — | 3 |
Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | — | — | 1 | 2 |
Cocaine-related disorders | D019970 | — | F14 | 1 | 2 | — | — | — | 2 |
Mood disorders | D019964 | EFO_0004247 | F30-F39 | — | 1 | — | — | — | 1 |
Ischemic stroke | D000083242 | — | — | — | 1 | — | — | — | 1 |
Ischemia | D007511 | EFO_0000556 | — | — | 1 | — | — | — | 1 |
Cerebral infarction | D002544 | — | I63 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Drug interactions | D004347 | — | — | 1 | — | — | — | 1 | 2 |
Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | — | 1 |
Body weight | D001835 | EFO_0004338 | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 2 | 2 |
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 1 | 1 |
Recurrence | D012008 | — | — | — | — | — | — | 1 | 1 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
Emergencies | D004630 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Perphenazine |
INN | perphenazine |
Description | Perphenazine is a phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist and an antiemetic. It is a member of phenothiazines, a N-alkylpiperazine, a N-(2-hydroxyethyl)piperazine and an organochlorine compound. It derives from a hydride of a 10H-phenothiazine. |
Classification | Small molecule |
Drug class | Typical antipsychotic |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 |
PDB | — |
CAS-ID | 58-39-9 |
RxCUI | — |
ChEMBL ID | CHEMBL567 |
ChEBI ID | 8028 |
PubChem CID | 4748 |
DrugBank | DB00850 |
UNII ID | FTA7XXY4EZ (ChemIDplus, GSRS) |