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Drug ReportsPelareorep
Pelareorep
Pelareorep is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Drug
Target
Variants
Financial
Trends
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
33 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.0251——8
Squamous cell carcinomaD002294———21——3
Squamous cell carcinoma of head and neckD000077195———11——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101—C90.061———6
Plasma cell neoplasmsD054219——61———6
Breast neoplasmsD001943EFO_0003869C5023———5
Pancreatic neoplasmsD010190EFO_0003860C2513———4
RecurrenceD012008——22———4
Lung neoplasmsD008175HP_0100526C34.90—3———3
AdenocarcinomaD000230——12———3
MelanomaD008545——13———3
Colorectal neoplasmsD015179——11———2
Non-small-cell lung carcinomaD002289———2———2
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369—C802————2
GliomaD005910EFO_0000520—2————2
AnemiaD000740HP_0001903D64.91————1
Brain neoplasmsD001932EFO_0003833C711————1
GlioblastomaD005909EFO_0000515—1————1
MedulloblastomaD008527——1————1
Rhabdoid tumorD018335——1————1
AstrocytomaD001254EFO_0000271—1————1
Diffuse intrinsic pontine gliomaD000080443——1————1
OligodendrogliomaD009837EFO_0000631—1————1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePelareorep
INN—
Description
Pelareorep (previously known under the trademark Reolysin) is a proprietary isolate of the unmodified human reovirus being developed as a systemically administered immuno-oncological viral agent for the treatment of solid tumors and hematological malignancies. Pelareorep is an oncolytic virus, which means that it preferentially lyses cancer cells. Pelareorep also promotes an inflamed tumor phenotype through innate and adaptive immune responses. Preliminary clinical trials indicate that it may have anti-cancer effects across a variety of cancer types (including breast, colorectal and pancreatic, as well as multiple myeloma) when administered alone and in combination with other cancer therapies.
Classification
Unknown
Drug class—
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL3545069
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID—
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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43 adverse events reported
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