Therapeutic Area | MeSH |
---|---|
hemic and lymphatic diseases | D006425 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
EMPAVELI | Apellis Pharmaceuticals | N-215014 RX | 2021-05-14 | 1 products, RLD, RS |
SYFOVRE | Apellis Pharmaceuticals | N-217171 RX | 2023-02-17 | 1 products, RLD, RS |
Expiration | Code | ||
---|---|---|---|
PEGCETACOPLAN, EMPAVELI, APELLIS PHARMS | |||
2028-05-14 | ODE-351 | ||
2026-05-14 | NCE | ||
2026-02-08 | M-288 | ||
PEGCETACOPLAN, SYFOVRE, APELLIS PHARMS | |||
2026-05-14 | NCE | ||
2026-02-22 | NP |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Pegcetacoplan, Empaveli, Apellis Pharms | |||
11844841 | 2038-12-09 | DP | U-3172, U-3173, U-3174 |
11040107 | 2038-04-09 | DP | U-3172, U-3173, U-3174 |
10035822 | 2033-11-15 | DP | |
10875893 | 2033-11-15 | DP | U-3124, U-3540 |
11292815 | 2033-11-15 | DS, DP | U-3124, U-3354, U-3540 |
10125171 | 2033-08-02 | DP | |
11661441 | 2033-01-13 | DP | U-3124, U-3540 |
7888323 | 2027-12-04 | DP | |
7989589 | 2027-12-04 | DP | |
9169307 | 2027-11-18 | DP | U-3123, U-3541 |
Pegcetacoplan, Syfovre, Apellis Pharms | |||
8168584 | 2027-04-07 | U-3540, U-3542 | |
9056076 | 2026-10-25 | U-3540 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hemolytic anemia autoimmune | D000744 | EFO_1001264 | D59.10 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Vascular diseases | D014652 | EFO_0004264 | I77 | — | 1 | — | — | — | 1 |
Thrombotic microangiopathies | D057049 | — | M31.1 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Paroxysmal hemoglobinuria | D006457 | Orphanet_447 | D59.12 | — | — | — | — | 1 | 1 |
Hemoglobinuria | D006456 | — | R82.3 | — | — | — | — | 1 | 1 |
Drug common name | Pegcetacoplan |
INN | pegcetacoplan |
Description | Pegcetacoplan, sold under the brand name Empaveli, among others, is a medication used to treat paroxysmal nocturnal hemoglobinuria and geographic atrophy of the retina. Pegcetacoplan is a complement inhibitor.
|
Classification | Protein |
Drug class | complement ligand inhibitors; PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | 2019171-69-6 |
RxCUI | — |
ChEMBL ID | CHEMBL4298211 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB16694 |
UNII ID | TO3JYR3BOU (ChemIDplus, GSRS) |