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Drug ReportsPegargiminase
Pegargiminase
Pegargiminase is an enzyme pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
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Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
231 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hepatitis cD006526—B19.231051116
HepatitisD006505—K75.91841—13
Chronic hepatitis cD019698EFO_0004220B18.2—651112
ArthritisD001168EFO_0005856M05-M14——44—8
LymphomaD008223—C85.927—1—8
Hepatitis aD006506EFO_0007305B151341—8
ConstipationD003248—K59.0—21216
Rheumatoid arthritisD001172EFO_0000685M06.9——14—5
Non-hodgkin lymphomaD008228—C85.9—4—1—5
Brain diseasesD001927—G93.4022—115
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938—C95683—419
Precursor cell lymphoblastic leukemia-lymphomaD054198—C91.0472—516
Lymphoid leukemiaD007945—C91462—313
Hepatocellular carcinomaD006528—C22.0462——10
MelanomaD008545——641——9
Parkinson diseaseD010300EFO_0002508G20——8——8
CarcinomaD002277—C80.0342——8
Liver neoplasmsD008113EFO_1001513C22.0442——8
Hiv infectionsD015658EFO_0000764B20—33——6
AnemiaD000740EFO_0004272D64.9—14——5
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic hepatitisD006521—K73.946———6
NeoplasmsD009369—C8062———6
Non-small-cell lung carcinomaD002289——41———4
Prostatic neoplasmsD011471—C6132———4
Chronic hepatitis bD019694EFO_0004239B18.114———4
Liver diseasesD008107EFO_0001421K70-K7734———4
Myeloid leukemia acuteD015470—C92.022———4
Breast neoplasmsD001943EFO_0003869C5021———3
Colorectal neoplasmsD015179——21——13
Virus diseasesD014777—B3433———3
Show 56 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———5———27
Renal cell carcinomaD002292EFO_0000376—2————2
Pancreatic neoplasmsD010190EFO_0003860C252————2
Uveal neoplasmsD014604EFO_1001230—2————2
Uveal melanomaD000098943——2————2
HyperuricemiaD033461——2————2
GoutD006073EFO_0004274M102————2
Retinal detachmentD012163EFO_0005773H33.21————1
Diabetic retinopathyD003930EFO_0003770—1————1
Acute diseaseD000208——1————1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.9————66
SclerosisD012598——————33
Cerebral palsyD002547—G80————22
Motor activityD009043EFO_0003940—————22
Macular edemaD008269——————11
EdemaD004487—R60.9————11
PapilledemaD010211EFO_1001074H35.81————11
OsteomyelitisD010019EFO_0003102M86————11
Transcranial direct current stimulationD065908——————11
Executive functionD056344——————11
Show 37 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePegargiminase
INNpegargiminase
Description
Pegargiminase (pegylated arginine deiminase)
Classification
Enzyme
Drug classenzymes; PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1394129-74-8
RxCUI—
ChEMBL IDCHEMBL3137346
ChEBI ID—
PubChem CID—
DrugBankDB06592
UNII ID0B7PYQ9YRT (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,575 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5 adverse events reported
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