Pascolizumab
Pascolizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against interleukin-4.
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Commercial
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Clinical
Clinical Trials
37 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | 1 | 1 | 3 | 1 | 1 | 6 |
| Dermatitis | D003872 | — | L30.9 | 1 | 1 | 3 | 1 | 1 | 6 |
| Asthma | D001249 | EFO_0000270 | J45 | — | 1 | — | 3 | 1 | 5 |
| Nasal polyps | D009298 | — | J33 | — | — | — | 2 | — | 2 |
| Eczema | D004485 | — | L30.9 | — | — | 1 | 1 | — | 2 |
| Rhinosinusitis | D000096825 | — | — | — | — | — | 1 | — | 1 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | 1 | — | 1 |
| Hypercholesterolemia | D006937 | — | — | — | — | — | 1 | — | 1 |
| Hyperlipoproteinemia type ii | D006938 | EFO_0004911 | E78.00 | — | — | — | 1 | — | 1 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | — | 1 | — | 1 |
Show 1 more
Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Allergic rhinitis | D065631 | — | J30.9 | 1 | 2 | — | — | — | 3 |
| Rhinitis | D012220 | EFO_0008521 | J31 | 1 | 2 | — | — | — | 3 |
| Urticaria | D014581 | EFO_0005531 | L50 | — | 2 | — | — | — | 2 |
| Leukemia | D007938 | — | C95 | 2 | 2 | — | — | — | 2 |
| Myelodysplastic syndromes | D009190 | — | D46 | 2 | 2 | — | — | — | 2 |
| Lymphoma | D008223 | — | C85.9 | 2 | 2 | — | — | — | 2 |
| Preleukemia | D011289 | — | — | 2 | 2 | — | — | — | 2 |
| Syndrome | D013577 | — | — | 1 | 1 | — | — | 1 | 2 |
| Chronic urticaria | D000080223 | — | L50.8 | — | 1 | — | — | — | 1 |
| Angioedema | D000799 | EFO_0005532 | T78.3 | — | 1 | — | — | — | 1 |
Show 23 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | — | 1 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | 1 | — | — | — | — | 1 |
| Body weight | D001835 | EFO_0004338 | — | 1 | — | — | — | — | 1 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | 1 | — | — | — | — | 1 |
| Ideal body weight | D056865 | — | — | 1 | — | — | — | — | 1 |
| Keratoconjunctivitis | D007637 | — | H16.2 | 1 | — | — | — | — | 1 |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | — | — | — | — | 1 | 1 |
| Disease | D004194 | EFO_0000408 | R69 | — | — | — | — | 1 | 1 |
| Duchenne muscular dystrophy | D020388 | EFO_0000429 | — | — | — | — | — | 1 | 1 |
| Muscular dystrophies | D009136 | EFO_0000757 | G71.0 | — | — | — | — | 1 | 1 |
| Systemic scleroderma | D012595 | EFO_0000717 | M34 | — | — | — | — | 1 | 1 |
| Localized scleroderma | D012594 | EFO_1001361 | L94.0 | — | — | — | — | 1 | 1 |
| Diffuse scleroderma | D045743 | EFO_0000404 | — | — | — | — | — | 1 | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | — | — | 1 | 1 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pascolizumab |
| INN | pascolizumab |
| Description | Pascolizumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108119 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | N1IOA09R6A (ChemIDplus, GSRS) |
Target
Agency Approved
IL4
IL4
Alternate
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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