Therapeutic Area | MeSH |
---|---|
digestive system diseases | D004066 |
stomatognathic diseases | D009057 |
Tradename | Proper name | Company | Number | Date | Products |
---|---|---|---|---|---|
Kepivance | palifermin | Orphan Medical | N-125103 RX | 2004-12-15 | 1 products |
Brand Name | Status | Last Update |
---|---|---|
kepivance | Biologic Licensing Application | 2024-12-20 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
mucositis | EFO_1001898 | D052016 | — |
Code | Description |
---|---|
J2425 | Injection, palifermin, 50 micrograms |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mucositis | D052016 | EFO_1001898 | — | 5 | 5 | 9 | 1 | — | 17 |
Lymphoma | D008223 | — | C85.9 | 5 | 7 | 1 | 1 | 2 | 14 |
Multiple myeloma | D009101 | — | C90.0 | 5 | 6 | 1 | 1 | 1 | 12 |
Plasma cell neoplasms | D054219 | — | — | 2 | 4 | 1 | 1 | 1 | 8 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | 4 | — | 1 | 2 | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Leukemia | D007938 | — | C95 | 5 | 7 | 2 | — | 1 | 14 |
Stomatitis | D013280 | EFO_1001904 | K12.1 | 4 | 5 | 7 | — | — | 13 |
Neoplasms | D009369 | — | C80 | 3 | 2 | 2 | — | — | 7 |
Hematologic neoplasms | D019337 | — | — | 2 | 2 | 1 | — | — | 5 |
Head and neck neoplasms | D006258 | — | — | 2 | 2 | 3 | — | — | 5 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | 1 | 1 | 1 | — | 1 | 4 |
Lymphoid leukemia | D007945 | — | C91 | — | — | 1 | — | 1 | 2 |
Radiation effects | D011830 | — | — | — | 1 | 1 | — | — | 2 |
Colonic neoplasms | D003110 | — | C18 | — | 1 | 1 | — | — | 1 |
Pain | D010146 | EFO_0003843 | R52 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myelodysplastic syndromes | D009190 | — | D46 | 2 | 5 | — | — | 1 | 7 |
Graft vs host disease | D006086 | — | D89.81 | 3 | 4 | — | — | 1 | 5 |
Hodgkin disease | D006689 | — | C81 | 1 | 3 | — | — | 1 | 4 |
Myeloid leukemia acute | D015470 | — | C92.0 | 1 | 2 | — | — | 1 | 4 |
Myeloid leukemia | D007951 | — | C92 | 1 | 2 | — | — | 1 | 4 |
Preleukemia | D011289 | — | — | 1 | 1 | — | — | 1 | 3 |
Syndrome | D013577 | — | — | 1 | 1 | — | — | 1 | 3 |
Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | — | 2 | — | — | 1 | 3 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | 1 | — | — | 1 | 2 |
B-cell lymphoma | D016393 | — | — | 1 | 1 | — | — | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hematopoietic stem cell transplantation | D018380 | — | — | 4 | — | — | — | — | 4 |
Neuroepithelial neoplasms | D018302 | — | — | 1 | — | — | — | — | 1 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Epidermolysis bullosa | D004820 | — | Q81 | 1 | — | — | — | — | 1 |
Epidermolysis bullosa dystrophica | D016108 | — | Q81.2 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mycoses | D009181 | — | B35-B49 | — | — | — | — | 1 | 1 |
Recurrence | D012008 | — | — | — | — | — | — | 1 | 1 |
Myeloproliferative disorders | D009196 | — | D47.1 | — | — | — | — | 1 | 1 |
Primary myelofibrosis | D055728 | — | D47.4 | — | — | — | — | 1 | 1 |
Sezary syndrome | D012751 | — | C84.1 | — | — | — | — | 1 | 1 |
B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | — | — | — | — | 1 | 1 |
Myelomonocytic leukemia chronic | D015477 | — | C93.1 | — | — | — | — | 1 | 1 |
Leukemia myeloid chronic atypical bcr-abl negative | D054438 | — | C92.2 | — | — | — | — | 1 | 1 |
Myelodysplastic-myeloproliferative diseases | D054437 | — | — | — | — | — | — | 1 | 1 |
B-cell lymphoma marginal zone | D018442 | — | C88.4 | — | — | — | — | 1 | 1 |
Drug common name | Palifermin |
INN | palifermin |
Description | Palifermin (trade name Kepivance, marketed by Biovitrum) is a truncated human recombinant keratinocyte growth factor (KGF) produced in Escherichia coli. KGF stimulates the growth of cells that line the surface of the mouth and intestinal tract.
|
Classification | Protein |
Drug class | growth factors: fibroblast growth factors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL1201821 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB00039 |
UNII ID | QMS40680K6 (ChemIDplus, GSRS) |