Oxaliplatin
Oxaliplatin (oxaliplatin) is a small molecule pharmaceutical. Oxaliplatin was first approved as Eloxatin on 2002-08-09. It is used to treat colorectal neoplasms, ovarian neoplasms, testicular neoplasms, and urinary bladder neoplasms in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Oxaliplatin (discontinued: Eloxatin, Oxaliplatin)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| oxaliplatin | ANDA | 2025-09-29 |
Indications
FDA
EMA
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
Code | Description |
|---|---|
| J9263 | Injection, oxaliplatin, 0.5 mg |
Clinical
Clinical Trials
3099 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 6 | 26 | 19 | 1 | 3 | 49 |
| Colonic neoplasms | D003110 | — | C18 | 1 | 2 | 1 | 1 | 1 | 6 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 2 | 17 | 2 | — | 1 | 20 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | 9 | 6 | — | — | 16 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 7 | 12 | 1 | — | 2 | 16 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 7 | 4 | — | — | 11 |
| Neoplasms | D009369 | — | C80 | 2 | 8 | 3 | — | — | 11 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 8 | 1 | — | — | 10 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | 4 | 2 | — | — | 7 |
| Lung neoplasms | D008175 | — | C34.90 | — | 5 | 1 | — | — | 5 |
| Carcinoma | D002277 | — | C80.0 | 1 | 2 | 2 | — | — | 4 |
| Neurotoxicity syndromes | D020258 | — | G92 | — | — | 2 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rectal neoplasms | D012004 | — | — | 3 | 13 | — | — | 2 | 16 |
| Esophageal neoplasms | D004938 | — | C15 | 1 | 8 | — | — | 1 | 9 |
| Adenocarcinoma | D000230 | — | — | 1 | 6 | — | — | 1 | 8 |
| Head and neck neoplasms | D006258 | — | — | — | 7 | — | — | — | 7 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 6 | — | — | — | 6 |
| Biliary tract neoplasms | D001661 | — | C24.9 | — | 5 | — | — | — | 5 |
| Recurrence | D012008 | — | — | — | 4 | — | — | — | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 2 | — | — | — | 3 |
| Gastrointestinal neoplasms | D005770 | — | C26.9 | — | 3 | — | — | — | 3 |
| Squamous cell carcinoma | D002294 | — | — | — | 3 | — | — | — | 3 |
Show 33 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peritoneal neoplasms | D010534 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Oxaliplatin |
| INN | oxaliplatin |
| Description | Oxaliplatin, sold under the brand name Eloxatin among others, is a cancer medication (platinum-based antineoplastic class) used to treat colorectal cancer. It is given by injection into a vein.
|
| Classification | Small molecule |
| Drug class | antineoplastics (platinum derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 61825-94-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL414804 |
| ChEBI ID | — |
| PubChem CID | 11947679 |
| DrugBank | DB00526 |
| UNII ID | 04ZR38536J (ChemIDplus, GSRS) |
Target
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Additional graphs summarizing 72,524 documents
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Safety
Black-box Warning
Black-box warning for: Oxaliplatin
Adverse Events
Top Adverse Reactions
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76,135 adverse events reported
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