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Drug ReportsOrgotein
Orgotein
Orgotein is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
M01: Antiinflammatory and antirheumatic products
M01A: Antiinflammatory and antirheumatic products, non-steroids
M01AX: Other antiinflammatory and antirheumatic agents, non-steroids in atc
M01AX14: Orgotein
HCPCS
No data
Clinical
Clinical Trials
65 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Diabetes mellitusD003920HP_0000819E08-E1311124
PeriodontitisD010518EFO_0000649K05.31214
Type 2 diabetes mellitusD003924EFO_0001360E1111113
Chronic periodontitisD055113EFO_0006343K05.3112
FrailtyD000073496R53.111
Male breast neoplasmsD01856711
Postoperative painD010149G89.1811
ParesthesiaD010292HP_0003401R20.211
SalivationD01247211
InfectionsD007239EFO_000054411
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Indications Phases 3
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients617
Male infertilityD007248EFO_0004248N46123
InfertilityD007246HP_0000789123
InflammationD007249MP_0001845112
CarcinomaD002277C80.011
Squamous cell carcinoma of head and neckD00007719511
Squamous cell carcinomaD00229411
Squamous cell neoplasmsD01830711
Sleep apnea syndromesD012891HP_0010535G47.311
HypoxiaD000860HP_0012418R09.0211
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Oxidative stressD018384EFO_100190566
Muscle strengthD05358033
Resistance trainingD05507033
Body compositionD00182322
Dental cariesD003731EFO_0003819K0222
Lipid peroxidationD01522711
Cardiovascular diseasesD002318HP_000162611
Cerebrovascular disordersD002561EFO_0003763I60-I6911
Breast neoplasmsD001943EFO_0003869C5011
CardiotoxicityD066126EFO_100148211
Show 35 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOrgotein
INNorgotein
Description
Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O−2) radical into ordinary molecular oxygen (O2) and hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive O−2.
Classification
Unknown
Drug class
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Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID
RxCUI
ChEMBL IDCHEMBL2108545
ChEBI ID
PubChem CID
DrugBank
UNII IDPKE82W49V1 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 70,021 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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4 adverse events reported
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