Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Colorectal neoplasms | D015179 | — | — | — | 1 | — | — | — | 1 |
Drug common name | ONVANSERTIB |
INN | onvansertib |
Description | Onvansertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against serine/threonine-protein kinase PLK1. In addition, it is known to target serine/threonine-protein kinase PLK2, serine/threonine-protein kinase PLK3, and receptor-type tyrosine-protein kinase FLT3. |
Classification | Small molecule |
Drug class | serine/threonine kinase inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCO)CC4)c2)CC1 |
PDB | — |
CAS-ID | 1034616-18-6 |
RxCUI | — |
ChEMBL ID | CHEMBL1738758 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | 67RM91WDHQ (ChemIDplus, GSRS) |