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Drug ReportsNeomycin
Neomycin
Casporyn, Coly-mycin, Cor-oticin, Cordran, Cortisporin, Lanabiotic, Lumi-sporyn, Maxitrol, Mycifradin, Mycitracin, Mytrex A, Neo-cort-dome, Neo-cortef, Neo-delta-cortef, Neo-fradin, Neo-hydeltrasol, Neo-medrol, Neo-polycin, Neobiotic, Neodecadron, Neosporin, Poly-pred, Statrol (neomycin) is an unknown pharmaceutical. Neomycin was first approved as Neo-cort-dome on 1982-01-01. It is used to treat bacterial infections, bacterial skin diseases, escherichia coli infections, and hepatic encephalopathy in the USA. It is known to target extracellular calcium-sensing receptor.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
digestive system diseasesD004066
nervous system diseasesD009422
skin and connective tissue diseasesD017437
nutritional and metabolic diseasesD009750
Trade Name
FDA
EMA
Combinations
Casporyn, Coly-mycin, Lumi-sporyn, Maxitrol (generic drugs available since 1982-01-01, discontinued: Cor-oticin, Cordran, Cortisporin, Dexacidin, Dexasporin, Lanabiotic, Mycitracin, Mytrex a, Neo-cort-dome, Neo-cortef, Neo-delta-cortef, Neo-hydeltrasol, Neo-medrol, Neo-polycin, Neodecadron, Neosporin, Oticair, Otobione, Otocort, Pediotic, Poly-pred, Statrol)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acetic acid
+
glacial
+
Hydrocortisone
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
NEO-CORT-DOMEBayerN-050238 DISCN1982-01-01
1 products
Hide discontinued
Bacitracin zinc
+
Hydrocortisone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CORTISPORINCasper PharmaN-050416 DISCN1982-01-01
1 products, RLD
CORTISPORINMonarch PharmaceuticalsN-050168 DISCN1984-05-04
1 products, RLD
Hide discontinued
Bacitracin zinc
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
LUMI-SPORYNCasper PharmaN-050417 RX1982-01-01
1 products, RLD
Colistin sulfate
+
Hydrocortisone acetate
+
Neomycin sulfate
+
Thonzonium bromide
Tradename
Company
Number
Date
Products
COLY-MYCIN SEndoN-050356 RX1982-01-01
1 products, RLD, RS
Dexamethasone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
MAXITROLHarrowN-050023 RX1982-01-01
1 products, RLD, RS
MAXITROLSandozN-050065 RX1982-01-01
1 products, RLD, RS
Dexamethasone sodium phosphate
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
NEODECADRONMerck KGaAN-050322 DISCN1982-01-01
1 products
NEODECADRONMerck KGaAN-050324 DISCN1982-01-01
1 products
Hide discontinued
Flurandrenolide
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
CORDRAN NEli LillyN-050345 DISCN1982-01-01
1 products
CORDRAN NEli LillyN-050346 DISCN1982-01-01
1 products
Hide discontinued
Hydrocortisone
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
NEO-CORT-DOMEBayerN-050237 DISCN1984-06-05
2 products
Hide discontinued
Hydrocortisone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CASPORYN HCCasper PharmaN-060613 RX1982-01-01
1 products, RLD, RS
Show 2 discontinued
Hydrocortisone acetate
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CORTISPORINMonarch PharmaceuticalsN-050218 DISCN1985-08-09
1 products, RLD
Hide discontinued
Neomycin sulfate
Tradename
Company
Number
Date
Products
MYCIFRADINPharmacia & UpjohnN-050285 DISCN1982-01-01
1 products
Hide discontinued
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
STATROLAlcon ResearchN-050344 DISCN1982-01-01
1 products
STATROLAlcon ResearchN-050456 DISCN1982-01-01
1 products
NEOSPORINGSKN-050176 DISCN1985-01-14
1 products
Hide discontinued
Neomycin sulfate
+
Polymyxin b sulfate
+
Prednisolone acetate
Tradename
Company
Number
Date
Products
POLY-PREDAllerganN-050081 DISCN1982-01-01
1 products
Hide discontinued
Neomycin sulfate
+
Prednisolone sodium phosphate
Tradename
Company
Number
Date
Products
NEO-HYDELTRASOLMerck KGaAN-050378 DISCN1982-01-01
1 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
10 person ansiOTC monograph final2010-06-07
25 person ansiOTC monograph final2010-06-07
4017 first aid kit 4022 first aid kitunapproved drug other2024-01-22
4032 first aid kitunapproved drug other2024-01-22
4056 first aid kit 4068 first aid kit 4081 first aid kit 4082 first aid kit 4083 first aid kit 4084 first aid kit 4085 first aid kit 4086 first aid...unapproved drug other2024-01-22
4064 first aid kit 4065 first aid kit 4066 first aid kit 4067 first aid kitunapproved drug other2024-01-22
4069 first aid kitunapproved drug other2019-03-10
4076 first aid kitunapproved drug other2019-03-17
4091 first aid kit 4092 first aid kit 4093 first aid kit 4094 first aid kit 4095 first aid kit 4096 first aid kitunapproved drug other2019-01-16
4097 first aid kit 4098 first aid kit 4099 first aid kit 4100 first aid kit 4101 first aid kit 4102 first aid kit 4103 first aid kit 4104 first aid...unapproved drug other2024-01-22
Show 370 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
hepatic encephalopathy—D006501K72.91
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AB: Antiinfectives and antiseptics for local oral treatment
— A01AB08: Neomycin
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07A: Intestinal antiinfectives
— A07AA: Antibiotics, intestinal
— A07AA01: Neomycin
— A07AA51: Neomycin, combinations
B: Blood and blood forming organ drugs
— B05: Blood substitutes and perfusion solutions
— B05C: Irrigating solutions, blood substitutes and perfusion
— B05CA: Antiinfective irrigating solutions
— B05CA09: Neomycin
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06A: Antibiotics for topical use
— D06AX: Other antibiotics for topical use in atc
— D06AX04: Neomycin
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01G: Aminoglycoside antibacterials
— J01GB: Other aminoglycosides in atc
— J01GB05: Neomycin
R: Respiratory system drugs
— R02: Throat preparations
— R02A: Throat preparations
— R02AB: Antibiotic throat preparations
— R02AB01: Neomycin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA03: Neomycin
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA07: Neomycin
— S03: Ophthalmological and otological preparations
— S03A: Antiinfectives, ophthalmologic and otologic
— S03AA: Antiinfectives
— S03AA01: Neomycin
HCPCS
No data
Clinical
Clinical Trials
261 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Castration-resistant prostatic neoplasmsD064129——61161120
Ventilator-associated pneumoniaD053717EFO_1001865J95.851—4112216
InfectionsD007239EFO_0000544—1—42411
Cystic fibrosisD003550EFO_0000390E841134—9
BacteremiaD016470EFO_0003033R78.81—24149
Dental pulp necrosisD003790—K04.13——227
Colorectal neoplasmsD015179——12—216
Bacterial infectionsD001424—A49112115
Healthcare-associated pneumoniaD000077299———131—4
Surgical wound infectionD013530——1——214
Show 25 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471—C612122—117
SepsisD018805HP_0100806A41.9112—36
PneumoniaD011014EFO_0003106—1—3—15
NeoplasmsD009369—C80331——4
Healthy volunteers/patients———1—3——4
Bacterial pneumoniaD018410EFO_1001272J15.9——1—12
Acute kidney injuryD058186HP_0001919N17——1—12
Septic shockD012772—A48.3——1——1
Iatrogenic diseaseD007049————1——1
BronchitisD001991—J40——1——1
Show 8 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C5011——34
Hodgkin diseaseD006689—C8121———3
AdenocarcinomaD000230———2———2
Non-small-cell lung carcinomaD002289——21———2
Crohn diseaseD003424EFO_0000384K50—2———2
DengueD003715—A9012———2
Anastomotic leakD057868———1——12
Neoadjuvant therapyD020360———2———2
Pseudomonas aeruginosaD011550NCBITaxon_287——1———1
Otitis externaD010032EFO_0009560H60—1———1
Show 7 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pseudomonas infectionsD011552EFO_0001076A41.521———12
Ulcerative colitisD003093EFO_0000729K511———12
Inflammatory bowel diseasesD015212EFO_0003767—1———12
Hepatic encephalopathyD006501—K72.911———12
Non-hodgkin lymphomaD008228—C85.92————2
OsteomyelitisD010019EFO_0003102M861————1
Diet therapyD004035——1————1
Pneumococcal infectionsD011008EFO_0000772J131————1
Gram-negative bacteriaD006090——1————1
RetinoblastomaD012175——1————1
Show 10 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Liver cirrhosisD008103EFO_0001422K74.0————22
Pancreatic cystD010181HP_0001737K86.2————22
Periapical diseasesD010483EFO_0010688—————11
Klebsiella pneumoniaeD007711NCBITaxon_573B96.1————11
Corneal diseasesD003316—H18.9————11
InflammationD007249MP_0001845—————11
PterygiumD011625—H11.0————11
PancreatitisD010195HP_0001733K85————11
Adrenal insufficiencyD000309——————11
Necrotizing enterocolitisD020345EFO_0003928K55.3————11
Show 26 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNeomycin
INNneomycin
Description
Framycetin is a tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. It has a role as an antibacterial drug, an allergen and an Escherichia coli metabolite. It is a conjugate base of a framycetin(6+).
Classification
Unknown
Drug classantibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1404-04-2
RxCUI7299
ChEMBL IDCHEMBL3989751
ChEBI ID—
PubChem CID8378
DrugBankDB00994
UNII IDI16QD7X297 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CASR
CASR
Organism
Homo sapiens
Gene name
CASR
Gene synonyms
GPRC2A, PCAR1
NCBI Gene ID
846
Protein name
extracellular calcium-sensing receptor
Protein synonyms
parathyroid Ca(2+)-sensing receptor 1, Parathyroid cell calcium-sensing receptor 1, PCaR1
Uniprot ID
Q4PJ19
Mouse ortholog
Casr (12374)
extracellular calcium-sensing receptor (Q9R1Y2)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Neomycin
+
Bacitracin
+
Polymyxin b
Total medical expenditures per year (USD, in millions)
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Neomycin
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Dexamethasone
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Neomycin
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Dexamethasone
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Polymyxin b
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Neomycin
+
Gramicidin
+
Polymyxin b
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Neomycin
+
Hydrocortisone
+
Polymyxin b
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Neomycin
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Neomycin
+
Polymyxin b
+
Pramoxine
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Neomycin
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Prednisolone
+
Polymyxin b
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 61,941 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,688 adverse events reported
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