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Drug ReportsNeomycin
Neomycin
/ Neomycin / Polymyxin B, Bacitracin / Hydrocortisone / Neomycin / Polymyxin B, Bacitracin / Neomycin / Polymyxin B, Casporyn, Coly-mycin, Cor-oticin, Cordran, Cortisporin, Dexasporin, Hydrocortisone / Neomycin / Polymyxin B, Lumi-sporyn, Maxitrol, Mycitracin, Mytrex A, Neo-cort-dome, Neo-cortef, Neo-delta-cortef, Neo-hydeltrasol, Neo-medrol, Neo-synalar, Neodecadron, Neomycin, Neomycin / Polymyxin B, Neosporin, Oticair, Poly-pred (neomycin) is an unknown pharmaceutical. Neomycin was first approved as Neo-cort-dome on 1982-01-01. It is used to treat bacterial infections, bacterial skin diseases, escherichia coli infections, and hepatic encephalopathy in the USA. It is known to target extracellular calcium-sensing receptor.
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1M
3M
6M
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2Y
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FDA approval date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
digestive system diseasesD004066
nervous system diseasesD009422
skin and connective tissue diseasesD017437
nutritional and metabolic diseasesD009750
Trade Name
FDA
EMA
Neomycin (discontinued: Mycifradin, Neobiotic, Neomycin)
Combinations
Bacitracin-neomycin-polymyxin w/ hydrocortisone, Casporyn, Coly-mycin, Dexasporin, Lumi-sporyn, Maxitrol, Neo-synalar, Neomycin polymyxin b, Neomycin polymyxin b sulfates bacitracin, Neomycin polymyxin b sulfates dexamethasone, Neomycin polymyxin b sulfates gramicidin, Neomycin polymyxin b sulfates hydrocortisone, Neomycin polymyxin b sulfates, bacitracin hydrocortisone, Neosporin, Neosporin g.u. irrigant, Oticair (discontinued: Bacitracin-neomycin-polymyxin, Bacitracin-neomycin-polymyxin w/ hydrocortisone, Cor-oticin, Cordran, Cortisporin, Dexacidin, Lanabiotic, Mycitracin, Mytrex a, Neo-cort-dome, Neo-cortef, Neo-delta-cortef, Neo-hydeltrasol, Neo-medrol, Neo-polycin, Neodecadron, Neomycin dexamethasone, Neomycin polymyxin b sulfates bacitracin, Neomycin polymyxin b sulfates dexamethasone, Neomycin polymyxin b sulfates gramicidin, Neomycin polymyxin b sulfates hydrocortisone, Neomycin polymyxin b sulfates, bacitracin hydrocortisone, Neomycin sulfate-dexamethasone, Neomycin sulfate-triamcinolone, Neosporin, Otobione, Otocort, Pediotic, Poly-pred, Statrol)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
STATROLAlcon ResearchN-050344 DISCN1982-01-01
1 products
STATROLAlcon ResearchN-050456 DISCN1982-01-01
1 products
NEOSPORINGSKN-050176 DISCN1985-01-14
1 products
Hide discontinued
Dexamethasone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
MAXITROLHarrowN-050023 RX1982-01-01
1 products, RLD, RS
MAXITROLSandozN-050065 RX1982-01-01
1 products, RLD, RS
Neomycin sulfate
+
Prednisolone sodium phosphate
Tradename
Company
Number
Date
Products
NEO-HYDELTRASOLMerck & CoN-050378 DISCN1982-01-01
1 products
Hide discontinued
Dexamethasone sodium phosphate
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
NEODECADRONMerck & CoN-050322 DISCN1982-01-01
1 products
NEODECADRONMerck & CoN-050324 DISCN1982-01-01
1 products
Hide discontinued
Neomycin sulfate
+
Polymyxin b sulfate
+
Prednisolone acetate
Tradename
Company
Number
Date
Products
POLY-PREDAllerganN-050081 DISCN1982-01-01
1 products
Hide discontinued
Acetic acid
+
glacial
+
Hydrocortisone
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
NEO-CORT-DOMEBayerN-050238 DISCN1982-01-01
1 products
Hide discontinued
Hydrocortisone
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
NEO-CORT-DOMEBayerN-050237 DISCN1984-06-05
2 products
Hide discontinued
Flurandrenolide
+
Neomycin sulfate
Tradename
Company
Number
Date
Products
CORDRAN NEli LillyN-050345 DISCN1982-01-01
1 products
CORDRAN NEli LillyN-050346 DISCN1982-01-01
1 products
Hide discontinued
Neomycin sulfate
Tradename
Company
Number
Date
Products
MYCIFRADINPharmacia & UpjohnN-050285 DISCN1982-01-01
1 products
Hide discontinued
Colistin sulfate
+
Hydrocortisone acetate
+
Neomycin sulfate
+
Thonzonium bromide
Tradename
Company
Number
Date
Products
COLY-MYCIN SEndoN-050356 RX1982-01-01
1 products, RLD, RS
Bacitracin zinc
+
Hydrocortisone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CORTISPORINCasper PharmaN-050416 DISCN1982-01-01
1 products, RLD
CORTISPORINMonarch PharmaceuticalsN-050168 DISCN1984-05-04
1 products, RLD
Hide discontinued
Hydrocortisone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CASPORYN HCCasper PharmaN-060613 RX1982-01-01
1 products, RLD, RS
Show 2 discontinued
Hydrocortisone acetate
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CORTISPORINMonarch PharmaceuticalsN-050218 DISCN1985-08-09
1 products, RLD
Hide discontinued
Bacitracin zinc
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
LUMI-SPORYNCasper PharmaN-050417 RX1982-01-01
1 products, RLD
Labels
FDA
EMA
Brand Name
Status
Last Update
OTC monograph final2012-08-10
10 person ansiOTC monograph final2010-06-07
25 person ansiOTC monograph final2010-06-07
4314 first aid kit 4315 first aid kitunapproved drug other2019-05-10
50 person ansiOTC monograph final2010-06-07
acme first aid contains 404 piecesOTC monograph final2010-06-07
acme small cuts and burnsOTC monograph final2010-06-14
adventure first aid .5 tinOTC monograph not final2017-03-16
adventure medical kits 1-2 person first aidOTC monograph not final2011-01-11
adventure medical kits 1-2 person national ski patrol first aidOTC monograph not final2010-11-10
Show 309 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
hepatic encephalopathy—D006501K72.91
shock—D012769R57.1
wounds and injuries—D014947T14.8
ulcerative colitisEFO_0000729D003093K51
pruritus ani—D011538L29.0
gastrointestinal diseases—D005767—
pneumoniaEFO_0003106D011014J18
Show 78 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AB: Antiinfectives and antiseptics for local oral treatment
— A01AB08: Neomycin
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07A: Intestinal antiinfectives
— A07AA: Antibiotics, intestinal
— A07AA01: Neomycin
— A07AA51: Neomycin, combinations
B: Blood and blood forming organ drugs
— B05: Blood substitutes and perfusion solutions
— B05C: Irrigating solutions, blood substitutes and perfusion
— B05CA: Antiinfective irrigating solutions
— B05CA09: Neomycin
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06A: Antibiotics for topical use
— D06AX: Other antibiotics for topical use in atc
— D06AX04: Neomycin
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01G: Aminoglycoside antibacterials
— J01GB: Other aminoglycosides in atc
— J01GB05: Neomycin
R: Respiratory system drugs
— R02: Throat preparations
— R02A: Throat preparations
— R02AB: Antibiotic throat preparations
— R02AB01: Neomycin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA03: Neomycin
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA07: Neomycin
— S03: Ophthalmological and otological preparations
— S03A: Antiinfectives, ophthalmologic and otologic
— S03AA: Antiinfectives
— S03AA01: Neomycin
HCPCS
No data
Clinical
Clinical Trials
75 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DengueD003715—A9012———2
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MalariaD008288EFO_0001068B541————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNeomycin
INNneomycin
Description
Framycetin is a tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. It has a role as an antibacterial drug, an allergen and an Escherichia coli metabolite. It is a conjugate base of a framycetin(6+).
Classification
Unknown
Drug classantibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID1404-04-2
RxCUI7299
ChEMBL IDCHEMBL3989751
ChEBI ID—
PubChem CID8378
DrugBankDB00994
UNII IDI16QD7X297 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CASR
CASR
Organism
Homo sapiens
Gene name
CASR
Gene synonyms
GPRC2A, PCAR1
NCBI Gene ID
846
Protein name
extracellular calcium-sensing receptor
Protein synonyms
parathyroid Ca(2+)-sensing receptor 1, Parathyroid cell calcium-sensing receptor 1, PCaR1
Uniprot ID
Q4PJ19
Mouse ortholog
Casr (12374)
extracellular calcium-sensing receptor (Q9R1Y2)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Neomycin
+
Bacitracin
+
Polymyxin b
Total medical expenditures per year (USD, in millions)
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Neomycin
+
Dexamethasone
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Neomycin
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Dexamethasone
+
Polymyxin b
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Neomycin
+
Gramicidin
+
Polymyxin b
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Neomycin
+
Hydrocortisone
+
Polymyxin b
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Neomycin
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Neomycin
+
Polymyxin b
+
Pramoxine
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Neomycin
+
Prednisolone
+
Polymyxin b
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 66,740 documents
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Safety
Black-box Warning
Black-box warning for: Neomycin sulfate
Adverse Events
Top Adverse Reactions
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5,079 adverse events reported
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