Neomycin
/ Neomycin / Polymyxin B, Bacitracin / Hydrocortisone / Neomycin / Polymyxin B, Bacitracin / Neomycin / Polymyxin B, Casporyn, Coly-mycin, Cor-oticin, Cordran, Cortisporin, Dexasporin, Hydrocortisone / Neomycin / Polymyxin B, Lumi-sporyn, Maxitrol, Mycitracin, Mytrex A, Neo-cort-dome, Neo-cortef, Neo-delta-cortef, Neo-hydeltrasol, Neo-medrol, Neo-synalar, Neodecadron, Neomycin, Neomycin / Polymyxin B, Neosporin, Oticair, Poly-pred (neomycin) is an unknown pharmaceutical. Neomycin was first approved as Neo-cort-dome on 1982-01-01. It is used to treat bacterial infections, bacterial skin diseases, escherichia coli infections, and hepatic encephalopathy in the USA. It is known to target extracellular calcium-sensing receptor.
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Commercial
Trade Name
FDA
EMA
Neomycin (discontinued: Mycifradin, Neobiotic, Neomycin)
CombinationsCasporyn, Coly-mycin, Dexasporin, Lumi-sporyn, Maxitrol, Neo-synalar, Neomycin polymyxin b, Neomycin polymyxin b sulfates bacitracin, Neomycin polymyxin b sulfates dexamethasone, Neomycin polymyxin b sulfates gramicidin, Neomycin polymyxin b sulfates hydrocortisone, Neomycin polymyxin b sulfates, bacitracin hydrocortisone, Oticair (discontinued: Bacitracin-neomycin-polymyxin, Bacitracin-neomycin-polymyxin w/ hydrocortisone, Cor-oticin, Cordran, Cortisporin, Dexacidin, Lanabiotic, Mycitracin, Mytrex a, Neo-cort-dome, Neo-cortef, Neo-delta-cortef, Neo-hydeltrasol, Neo-medrol, Neo-polycin, Neodecadron, Neomycin dexamethasone, Neomycin polymyxin b, Neomycin polymyxin b sulfates bacitracin, Neomycin polymyxin b sulfates dexamethasone, Neomycin polymyxin b sulfates gramicidin, Neomycin polymyxin b sulfates hydrocortisone, Neomycin polymyxin b sulfates, bacitracin hydrocortisone, Neomycin sulfate-dexamethasone, Neomycin sulfate-triamcinolone, Neosporin, Neosporin g.u. irrigant, Otobione, Otocort, Pediotic, Poly-pred, Statrol)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Neomycin sulfate
+
Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| STATROL | Alcon Research | N-050344 DISCN | 1982-01-01 | 1 products |
| STATROL | Alcon Research | N-050456 DISCN | 1982-01-01 | 1 products |
| NEOSPORIN | GSK | N-050176 DISCN | 1985-01-14 | 1 products |
Hide discontinued
Dexamethasone
+
Neomycin sulfate
+
Polymyxin b sulfate
Neomycin sulfate
+
Prednisolone sodium phosphate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| NEO-HYDELTRASOL | Merck & Co | N-050378 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Dexamethasone sodium phosphate
+
Neomycin sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| NEODECADRON | Merck & Co | N-050322 DISCN | 1982-01-01 | 1 products |
| NEODECADRON | Merck & Co | N-050324 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Neomycin sulfate
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Polymyxin b sulfate
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Prednisolone acetate
Acetic acid
+
glacial
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Hydrocortisone
+
Neomycin sulfate
Hydrocortisone
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Neomycin sulfate
Flurandrenolide
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Neomycin sulfate
Neomycin sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| MYCIFRADIN | Pharmacia & Upjohn | N-050285 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Colistin sulfate
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Hydrocortisone acetate
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Neomycin sulfate
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Thonzonium bromide
Bacitracin zinc
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Hydrocortisone
+
Neomycin sulfate
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Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CORTISPORIN | Casper Pharma | N-050416 DISCN | 1982-01-01 | 1 products, RLD |
| CORTISPORIN | Monarch Pharmaceuticals | N-050168 DISCN | 1984-05-04 | 1 products, RLD |
Hide discontinued
Hydrocortisone
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Neomycin sulfate
+
Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CASPORYN HC | Casper Pharma | N-060613 RX | 1982-01-01 | 1 products, RLD, RS |
Show 2 discontinued
Hydrocortisone acetate
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CORTISPORIN | Monarch Pharmaceuticals | N-050218 DISCN | 1985-08-09 | 1 products, RLD |
Hide discontinued
Bacitracin zinc
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| LUMI-SPORYN | Casper Pharma | N-050417 RX | 1982-01-01 | 1 products, RLD |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| OTC monograph final | 2012-08-10 | |
| 10 person ansi | OTC monograph final | 2010-06-07 |
| 25 person ansi | OTC monograph final | 2010-06-07 |
| 4314 first aid kit 4315 first aid kit | unapproved drug other | 2019-05-10 |
| 50 person ansi | OTC monograph final | 2010-06-07 |
| acme first aid contains 404 pieces | OTC monograph final | 2010-06-07 |
| acme small cuts and burns | OTC monograph final | 2010-06-14 |
| adventure first aid .5 tin | OTC monograph not final | 2017-03-16 |
| adventure medical kits 1-2 person first aid | OTC monograph not final | 2011-01-11 |
| adventure medical kits 1-2 person national ski patrol first aid | OTC monograph not final | 2010-11-10 |
Show 312 more
Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
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ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AB: Antiinfectives and antiseptics for local oral treatment
— A01AB08: Neomycin
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07A: Intestinal antiinfectives
— A07AA: Antibiotics, intestinal
— A07AA01: Neomycin
— A07AA51: Neomycin, combinations
B: Blood and blood forming organ drugs
— B05: Blood substitutes and perfusion solutions
— B05C: Irrigating solutions, blood substitutes and perfusion
— B05CA: Antiinfective irrigating solutions
— B05CA09: Neomycin
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06A: Antibiotics for topical use
— D06AX: Other antibiotics for topical use in atc
— D06AX04: Neomycin
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01G: Aminoglycoside antibacterials
— J01GB: Other aminoglycosides in atc
— J01GB05: Neomycin
R: Respiratory system drugs
— R02: Throat preparations
— R02A: Throat preparations
— R02AB: Antibiotic throat preparations
— R02AB01: Neomycin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA03: Neomycin
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA07: Neomycin
— S03: Ophthalmological and otological preparations
— S03A: Antiinfectives, ophthalmologic and otologic
— S03AA: Antiinfectives
— S03AA01: Neomycin
HCPCS
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Clinical
Clinical Trials
78 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Surgical wound infection | D013530 | — | — | 1 | — | — | 3 | 3 | 7 |
| Colorectal neoplasms | D015179 | — | — | 1 | 1 | — | 1 | 1 | 4 |
| Medication adherence | D055118 | EFO_0006344 | — | — | — | — | 1 | 1 | 2 |
| Patient compliance | D010349 | — | — | — | — | — | 1 | 1 | 2 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | 1 | — | 1 | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | — | — | 1 | — | 2 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 1 | — | — | 1 | — | 2 |
| Postoperative complications | D011183 | — | — | — | — | — | 1 | 1 | 2 |
| Rectal neoplasms | D012004 | — | — | — | 1 | — | 1 | — | 2 |
| Vaginitis | D014627 | EFO_0005757 | N76 | — | — | 1 | 1 | — | 2 |
Show 12 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bites and stings | D001733 | — | — | — | — | 1 | — | 1 | 2 |
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | 1 | 1 | — | — | 1 |
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | 1 | 1 | — | — | 1 |
| Bacterial conjunctivitis | D003234 | EFO_1000829 | H10.0 | — | — | 1 | — | — | 1 |
| Conjunctivitis | D003231 | — | H10 | — | — | 1 | — | — | 1 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 1 | — | — | 1 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | 1 | — | — | 1 |
| Hemorrhoids | D006484 | EFO_0009552 | K64 | — | — | 1 | — | — | 1 |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | — | 1 | — | — | 1 |
| Vesico-ureteral reflux | D014718 | EFO_0007536 | N13.7 | — | — | 1 | — | — | 1 |
Show 3 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hematopoietic stem cell transplantation | D018380 | — | — | — | 1 | — | — | 1 | 2 |
| Crohn disease | D003424 | EFO_0000384 | K50 | — | 2 | — | — | — | 2 |
| Dengue | D003715 | — | A90 | 1 | 2 | — | — | — | 2 |
| Anastomotic leak | D057868 | — | — | — | 1 | — | — | 1 | 2 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | — | 1 | — | — | — | 1 |
| Glucose intolerance | D018149 | HP_0000833 | R73.03 | — | 1 | — | — | — | 1 |
| Otitis externa | D010032 | EFO_0009560 | H60 | — | 1 | — | — | — | 1 |
| Oral lichen planus | D017676 | — | — | — | 1 | — | — | — | 1 |
| Lichen planus | D008010 | — | L43 | — | 1 | — | — | — | 1 |
| Anaphylaxis | D000707 | — | T78.2 | — | 1 | — | — | — | 1 |
Show 5 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | 1 | — | — | — | 2 | 3 |
| Communicable diseases | D003141 | — | — | 2 | — | — | — | 1 | 3 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 3 | — | — | — | — | 3 |
| Lymphoma | D008223 | — | C85.9 | 3 | — | — | — | — | 3 |
| Hodgkin disease | D006689 | — | C81 | 3 | — | — | — | — | 3 |
| Colitis | D003092 | EFO_0003872 | K52.9 | 1 | — | — | — | 1 | 2 |
| Ulcer | D014456 | MPATH_579 | — | 1 | — | — | — | 1 | 2 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | — | — | — | 1 | 2 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 1 | — | — | — | 1 | 2 |
| Infections | D007239 | EFO_0000544 | — | 2 | — | — | — | — | 2 |
Show 17 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Corneal diseases | D003316 | — | H18.9 | — | — | — | — | 1 | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
| Pterygium | D011625 | — | H11.0 | — | — | — | — | 1 | 1 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | — | — | 1 | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | — | — | — | 1 | 1 |
| Herpes simplex | D006561 | — | B00 | — | — | — | — | 1 | 1 |
| Herpesviridae infections | D006566 | EFO_0007309 | B00.4 | — | — | — | — | 1 | 1 |
| Aids-related opportunistic infections | D017088 | — | — | — | — | — | — | 1 | 1 |
| Necrotizing enterocolitis | D020345 | EFO_0003928 | K55.3 | — | — | — | — | 1 | 1 |
| Intestinal obstruction | D007415 | — | K56.60 | — | — | — | — | 1 | 1 |
Show 26 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Neomycin |
| INN | neomycin |
| Description | Framycetin is a tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. It has a role as an antibacterial drug, an allergen and an Escherichia coli metabolite. It is a conjugate base of a framycetin(6+). |
| Classification | Unknown |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1404-04-2 |
| RxCUI | 7299 |
| ChEMBL ID | CHEMBL3989751 |
| ChEBI ID | — |
| PubChem CID | 8378 |
| DrugBank | DB00994 |
| UNII ID | I16QD7X297 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CASR
CASR
Organism
Homo sapiens
Gene name
CASR
Gene synonyms
GPRC2A, PCAR1
NCBI Gene ID
Protein name
extracellular calcium-sensing receptor
Protein synonyms
parathyroid Ca(2+)-sensing receptor 1, Parathyroid cell calcium-sensing receptor 1, PCaR1
Uniprot ID
Mouse ortholog
Casr (12374)
extracellular calcium-sensing receptor (Q9R1Y2)
Variants
No data
Financial
Revenue by drug
$
€
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Estimated US medical usage
Neomycin
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Bacitracin
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Polymyxin b
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Neomycin
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Dexamethasone
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Neomycin
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Dexamethasone
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Polymyxin b
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Neomycin
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Gramicidin
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Polymyxin b
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Neomycin
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Hydrocortisone
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Polymyxin b
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Neomycin
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Neomycin
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Polymyxin b
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Pramoxine
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Neomycin
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Prednisolone
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Polymyxin b
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PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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5,469 adverse events reported
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