Nedaplatin
Nedaplatin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
107 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal neoplasms | D004938 | — | C15 | 3 | 16 | 5 | 3 | — | 24 |
| Squamous cell carcinoma | D002294 | — | — | 2 | 13 | 3 | 1 | 2 | 19 |
| Squamous cell neoplasms | D018307 | — | — | — | 2 | — | 1 | — | 3 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | — | 15 | 5 | — | 6 | 26 |
| Carcinoma | D002277 | — | C80.0 | 3 | 17 | 5 | — | 4 | 25 |
| Nasopharyngeal carcinoma | D000077274 | — | — | 1 | 12 | 8 | — | 2 | 21 |
| Nasopharyngeal neoplasms | D009303 | — | — | 1 | 11 | 8 | — | 2 | 20 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | 3 | 12 | 2 | — | 2 | 17 |
| Lung neoplasms | D008175 | — | C34.90 | — | 8 | 1 | — | 2 | 11 |
| Recurrence | D012008 | — | — | — | 3 | 1 | — | — | 4 |
| Neoplasms | D009369 | — | C80 | 1 | 3 | 1 | — | 1 | 4 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | — | 3 | 1 | — | — | 4 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | 2 | — | — | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Uterine cervical neoplasms | D002583 | — | — | — | 4 | — | — | 2 | 6 |
| Small cell lung carcinoma | D055752 | — | — | — | 2 | — | — | 2 | 4 |
| Adenocarcinoma of lung | D000077192 | — | — | — | 2 | — | — | — | 2 |
| Thymoma | D013945 | — | — | — | 2 | — | — | — | 2 |
| Heavy ion radiotherapy | D063193 | — | — | — | 2 | — | — | — | 2 |
| Thymus neoplasms | D013953 | — | C37 | — | 1 | — | — | — | 1 |
| Salivary gland neoplasms | D012468 | EFO_0003826 | D11 | — | 1 | — | — | — | 1 |
| Head and neck neoplasms | D006258 | — | — | — | 1 | — | — | — | 1 |
| Lymphoma | D008223 | — | C85.9 | — | 1 | — | — | — | 1 |
| Central nervous system neoplasms | D016543 | — | — | — | 1 | — | — | — | 1 |
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Drug therapy | D004358 | — | — | — | — | — | — | 1 | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | — | — | — | 1 | 1 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | — | 1 | 1 |
| Magnetic resonance imaging | D008279 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nedaplatin |
| INN | nedaplatin |
| Description | Nedaplatin (INN, marketed under the tradename Aqupla) is a platinum-based antineoplastic drug which is used for cancer chemotherapy. The complex consists of two ammine ligands and the dianion derived from glycolic acid.
|
| Classification | Small molecule |
| Drug class | antineoplastics (platinum derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 95734-82-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3137685 |
| ChEBI ID | 31898 |
| PubChem CID | 6917890 |
| DrugBank | — |
| UNII ID | 8UQ3W6JXAN (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Additional graphs summarizing 3,448 documents
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Safety
Black-box Warning
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Adverse Events
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913 adverse events reported
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