Laquinimod
Laquinimod is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
17 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 4 | 6 | — | — | 10 |
| Sclerosis | D012598 | — | — | — | 3 | 6 | — | — | 9 |
| Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | 3 | 5 | — | — | 8 |
| Disease progression | D018450 | — | — | — | — | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | — | 2 | — | — | — | 2 |
| Lupus nephritis | D008181 | EFO_0005761 | — | — | 1 | — | — | — | 1 |
| Nephritis | D009393 | — | N05 | — | 1 | — | — | — | 1 |
| Chronic progressive multiple sclerosis | D020528 | EFO_0003840 | — | — | 1 | — | — | — | 1 |
| Huntington disease | D006816 | Orphanet_399 | G10 | — | 1 | — | — | — | 1 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | 1 | — | — | — | 1 |
| Lupus erythematosus panniculitis | D015435 | — | L93.2 | — | 1 | — | — | — | 1 |
| Crohn disease | D003424 | EFO_0000384 | K50 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
| Pharmacological phenomena | D000069437 | — | — | 1 | — | — | — | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Laquinimod |
| INN | laquinimod |
| Description | Laquinimod is an experimental immunomodulator developed by Active Biotech and Teva. It is being investigated as an oral treatment for multiple sclerosis (MS) and Huntington's disease.
|
| Classification | Small molecule |
| Drug class | immunomodulators |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCN(C(=O)c1c(O)c2c(Cl)cccc2n(C)c1=O)c1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 248282-07-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL66092 |
| ChEBI ID | — |
| PubChem CID | 216469 |
| DrugBank | — |
| UNII ID | 908SY76S4G (ChemIDplus, GSRS) |
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Safety
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