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Drug ReportsIncobotulinumtoxina
Incobotulinumtoxina
Xeomin (incobotulinumtoxina) is an unknown pharmaceutical. Incobotulinumtoxina was first approved as Xeomin on 2010-07-30. It is used to treat blepharospasm, dystonia, fissure in ano, genetic skin diseases, and muscle rigidity amongst others in the USA.
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Events Timeline
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
musculoskeletal diseasesD009140
digestive system diseasesD004066
nervous system diseasesD009422
eye diseasesD005128
hereditary congenital and neonatal diseases and abnormalitiesD009358
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Xeomin
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Incobotulinumtoxina
Tradename
Proper name
Company
Number
Date
Products
XeominincobotulinumtoxinAMerzN-125360 RX2010-07-30
3 products
Labels
FDA
EMA
Brand Name
Status
Last Update
xeominBiologic Licensing Application2024-12-19
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
209 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.9516
Dystonic disordersD020821G242215
DystoniaD004421HP_0001332G242215
TorticollisD014103HP_0000473F45.81214
Sleep bruxismD020186G47.6311
BruxismD002012F45.811
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Muscle spasticityD009128HP_00012571910
Cerebral palsyD002547G80145
Traumatic brain injuriesD000070642S06134
Brain injuriesD001930S06.9134
BlepharospasmD001764G24.51214
SialorrheaD012798HP_0002307K11.7123
Parkinson diseaseD010300EFO_0002508G20123
FaciesD01906622
Wounds and injuriesD014947T14.8112
Healthy volunteers/patients112
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Essential tremorD020329EFO_0003108G25.022
TremorD014202HP_0001337R25.122
ParesisD010291HP_000126922
ClubfootD003025HP_0008110Q66.011
Equinus deformityD00486311
ParaplegiaD010264HP_0001258G82.211
TalipesD000070558HP_0001883Q66.111
Obstructive sleep apneaD020181EFO_0003918G47.3311
SnoringD012913R06.8311
Sleep apnea syndromesD012891HP_0010535G47.311
Show 11 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Thoracic outlet syndromeD013901EFO_0007507G54.011
SyndromeD01357711
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameIncobotulinumtoxina
INN
Description
Botulinum toxin, or botulinum neurotoxin, is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes.
Classification
Neurotoxin
Drug class
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Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID
RxCUI
ChEMBL IDCHEMBL2108035
ChEBI ID
PubChem CID
DrugBankDB00083
UNII ID
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,180 documents
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Safety
Black-box Warning
Black-box warning for: Xeomin
Adverse Events
Top Adverse Reactions
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4,226 adverse events reported
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