Brand Name | Status | Last Update |
---|---|---|
xeomin | Biologic Licensing Application | 2024-12-19 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Stroke | D020521 | EFO_0000712 | I63.9 | — | — | 5 | 1 | — | 6 |
Dystonic disorders | D020821 | — | G24 | — | — | 2 | 2 | 1 | 5 |
Dystonia | D004421 | HP_0001332 | G24 | — | — | 2 | 2 | 1 | 5 |
Torticollis | D014103 | HP_0000473 | F45.8 | — | — | 1 | 2 | 1 | 4 |
Sleep bruxism | D020186 | — | G47.63 | — | — | — | 1 | — | 1 |
Bruxism | D002012 | — | F45.8 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Muscle spasticity | D009128 | HP_0001257 | — | — | 1 | 9 | — | — | 10 |
Cerebral palsy | D002547 | — | G80 | — | 1 | 4 | — | — | 5 |
Traumatic brain injuries | D000070642 | — | S06 | — | 1 | 3 | — | — | 4 |
Brain injuries | D001930 | — | S06.9 | — | 1 | 3 | — | — | 4 |
Blepharospasm | D001764 | — | G24.5 | — | 1 | 2 | — | 1 | 4 |
Sialorrhea | D012798 | HP_0002307 | K11.7 | — | 1 | 2 | — | — | 3 |
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | 2 | — | — | 3 |
Facies | D019066 | — | — | — | — | 2 | — | — | 2 |
Wounds and injuries | D014947 | — | T14.8 | — | 1 | 1 | — | — | 2 |
Healthy volunteers/patients | — | — | — | 1 | — | 1 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Essential tremor | D020329 | EFO_0003108 | G25.0 | — | 2 | — | — | — | 2 |
Tremor | D014202 | HP_0001337 | R25.1 | — | 2 | — | — | — | 2 |
Paresis | D010291 | HP_0001269 | — | — | 2 | — | — | — | 2 |
Clubfoot | D003025 | HP_0008110 | Q66.0 | — | 1 | — | — | — | 1 |
Equinus deformity | D004863 | — | — | — | 1 | — | — | — | 1 |
Paraplegia | D010264 | HP_0001258 | G82.2 | — | 1 | — | — | — | 1 |
Talipes | D000070558 | HP_0001883 | Q66.1 | — | 1 | — | — | — | 1 |
Obstructive sleep apnea | D020181 | EFO_0003918 | G47.33 | — | 1 | — | — | — | 1 |
Snoring | D012913 | — | R06.83 | — | 1 | — | — | — | 1 |
Sleep apnea syndromes | D012891 | HP_0010535 | G47.3 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Thoracic outlet syndrome | D013901 | EFO_0007507 | G54.0 | 1 | — | — | — | — | 1 |
Syndrome | D013577 | — | — | 1 | — | — | — | — | 1 |
Drug common name | Incobotulinumtoxina |
INN | — |
Description | Botulinum toxin, or botulinum neurotoxin, is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes.
|
Classification | Neurotoxin |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL2108035 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB00083 |
UNII ID | — |