
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| GUANIDINE HYDROCHLORIDE | Merck & Co | N-001546 DISCN | 1982-01-01 | 1 products |
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| muscle weakness | — | D018908 | — |
| lambert-eaton myasthenic syndrome | EFO_0020094 | D015624 | G70.80 |

Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 97 | 103 | 255 | 189 | 91 | 713 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 46 | 57 | 143 | 91 | 47 | 368 |
| Healthy volunteers/patients | — | — | — | 165 | 1 | — | 2 | 9 | 177 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | 12 | 20 | 27 | 43 | 52 | 145 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 9 | 25 | 29 | 40 | 30 | 128 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 11 | 19 | 11 | 35 | 24 | 95 |
| Syndrome | D013577 | — | — | 2 | 10 | 8 | 16 | 22 | 56 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | 5 | 10 | 11 | 15 | 13 | 51 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 8 | 28 | 5 | 3 | 8 | 50 |
| Gestational diabetes | D016640 | — | O24.4 | 3 | 7 | 16 | 14 | 11 | 47 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuroblastoma | D009447 | EFO_0000621 | — | 10 | 14 | 3 | — | 9 | 35 |
| Neoplasms | D009369 | — | C80 | 14 | 13 | 3 | — | 4 | 33 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 4 | 11 | 3 | — | 1 | 17 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | 14 | 1 | — | — | 15 |
| Colorectal neoplasms | D015179 | — | — | 1 | 10 | 2 | — | 1 | 14 |
| Pheochromocytoma | D010673 | — | — | 2 | 5 | 1 | — | 7 | 14 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 2 | 4 | 2 | — | 5 | 11 |
| Carcinoma | D002277 | — | C80.0 | 3 | 7 | 1 | — | 1 | 11 |
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | 5 | 4 | 1 | — | 1 | 10 |
| Covid-19 | D000086382 | — | U07.1 | — | 3 | 3 | — | 3 | 9 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 7 | 11 | — | — | 3 | 19 |
| Adenocarcinoma | D000230 | — | — | 1 | 10 | — | — | 1 | 12 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | 9 | — | — | — | 10 |
| Malaria | D008288 | EFO_0001068 | B54 | 4 | 2 | — | — | 4 | 9 |
| Melanoma | D008545 | — | — | 4 | 7 | — | — | — | 9 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | 6 | — | — | 2 | 8 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | 5 | — | — | 1 | 8 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 4 | 5 | — | — | — | 8 |
| Paraganglioma | D010235 | — | — | 2 | 3 | — | — | 4 | 8 |
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | 5 | — | — | — | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 9 | — | — | — | 2 | 11 |
| Muscular atrophy | D009133 | — | — | 3 | — | — | — | 3 | 6 |
| Pharmacokinetics | D010599 | — | — | 5 | — | — | — | — | 5 |
| Fatigue | D005221 | — | R53.83 | 2 | — | — | — | 3 | 5 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 1 | — | — | — | 3 | 4 |
| Lymphoid leukemia | D007945 | — | C91 | 2 | — | — | — | 2 | 4 |
| Drug interactions | D004347 | — | — | 4 | — | — | — | — | 4 |
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | 4 | — | — | — | — | 4 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | 2 | — | — | — | 2 | 4 |
| Diabetic retinopathy | D003930 | EFO_0003770 | — | 2 | — | — | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Oral hygiene | D009910 | — | — | — | — | — | — | 8 | 8 |
| Postoperative pain | D010149 | — | G89.18 | — | — | — | — | 7 | 7 |
| Brain concussion | D001924 | — | S06.0 | — | — | — | — | 4 | 4 |
| Physical fitness | D010809 | — | — | — | — | — | — | 3 | 3 |
| Hydrogen-ion concentration | D006863 | — | — | — | — | — | — | 3 | 3 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | — | — | 2 | 2 |
| Asthma | D001249 | EFO_0000270 | J45 | — | — | — | — | 2 | 2 |
| Disease-free survival | D018572 | EFO_0000409 | — | — | — | — | — | 2 | 2 |
| Pancreatitis | D010195 | EFO_0000278 | K85 | — | — | — | — | 2 | 2 |
| Essential hypertension | D000075222 | — | I10 | — | — | — | — | 2 | 2 |
| Drug common name | Guanidine |
| INN | — |
| Description | Guanidine is an aminocarboxamidine, the parent compound of the guanidines. It is a one-carbon compound, a member of guanidines and a carboxamidine. It is a conjugate base of a guanidinium. |
| Classification | Small molecule |
| Drug class | antihypertensives (guanidine deriviatives) |
| Image (chem structure or protein) | ![]() |
| Structure (InChI/SMILES or Protein Sequence) | N=C(N)N |

