Glucosamine
Glucosamine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target P2Y purinoceptor 14.
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Commercial
Therapeutic Areas
Trade Name
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Drug Products
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| acts38 boswelliagel | unapproved drug other | 2022-09-07 |
| acts38 boswelliagel (100ml) | unapproved drug other | 2022-10-22 |
| artridon | C200263 | 2024-10-29 |
| deguli | unapproved drug other | 2022-02-21 |
| floriva | unapproved drug other | 2024-02-02 |
| glucosamine cream extra strength | C200263 | 2024-12-30 |
| glucosamine sulfate, chondroitin sulfate, ibuprofen | Export only | 2025-06-30 |
| goodoh energycream | unapproved drug other | 2023-11-30 |
| implaheal p.ocream | unapproved drug other | 2020-01-04 |
| jba joint revive | unapproved drug other | 2025-03-31 |
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Indications
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Agency Specific
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HCPCS
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Clinical
Clinical Trials
141 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ankylosing spondylitis | D013167 | EFO_0003898 | M45 | — | — | — | — | 1 | 1 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | — | — | 1 | 1 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | — | 1 | 1 |
| Spondylarthritis | D025241 | — | — | — | — | — | — | 1 | 1 |
| Spondylitis | D013166 | — | M46.9 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Glucosamine |
| INN | glucosamine |
| Description | 2-amino-2-deoxy-D-glucopyranose is a D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2. It has a role as an Escherichia coli metabolite, a mouse metabolite and a geroprotector. It is functionally related to a D-glucopyranose. It is a conjugate base of a 2-ammonio-2-deoxy-D-glucopyranose. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O |
Identifiers
| PDB | — |
| CAS-ID | 3416-24-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL493287 |
| ChEBI ID | 47977 |
| PubChem CID | 439213 |
| DrugBank | DB01296 |
| UNII ID | N08U5BOQ1K (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
P2RY14
P2RY14
Organism
Homo sapiens
Gene name
P2RY14
Gene synonyms
GPR105, KIAA0001
NCBI Gene ID
Protein name
P2Y purinoceptor 14
Protein synonyms
G protein coupled receptor for UDP-glucose, G-protein coupled receptor 105, P2Y(14) receptor, P2Y14 receptor, purinergic receptor P2Y, G-protein coupled, 14, UDP-glucose receptor
Uniprot ID
Mouse ortholog
P2ry14 (140795)
P2Y purinoceptor 14 (Q9ESG6)
Variants
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Financial
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Estimated US medical usage
Glucosamine
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
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Additional graphs summarizing 55,463 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,743 adverse events reported
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