Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Leukemia | D007938 | — | C95 | — | 1 | — | — | — | 1 |
B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | — | 1 | — | — | — | 1 |
Lymphoid leukemia | D007945 | — | C91 | — | 1 | — | — | — | 1 |
Drug common name | Genistein |
INN | genistein |
Description | Genistein is a 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a phytoestrogen, a plant metabolite, a geroprotector and a human urinary metabolite. It is a conjugate acid of a genistein(1-). |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 |
PDB | — |
CAS-ID | 446-72-0 |
RxCUI | — |
ChEMBL ID | CHEMBL44 |
ChEBI ID | 28088 |
PubChem CID | 5280961 |
DrugBank | DB01645 |
UNII ID | DH2M523P0H (ChemIDplus, GSRS) |