Flurandrenolide
Cordran, Flurandrenolide (flurandrenolide) is a small molecule pharmaceutical. Flurandrenolide was first approved as Cordran on 1982-01-01. It is used to treat facial dermatoses, foot dermatoses, hand dermatoses, inflammation, and leg dermatoses in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Cordran, Flurandrenolide (discontinued: Cordran, Flurandrenolide)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Flurandrenolide
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cordran | New Drug Application | 2023-11-10 |
| flurandrenolide | ANDA | 2023-08-17 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| inflammation | MP_0001845 | D007249 | — |
| facial dermatoses | — | D005148 | — |
| foot dermatoses | — | D005533 | — |
| hand dermatoses | — | D006229 | — |
| leg dermatoses | — | D007868 | — |
| bacterial infections | — | D001424 | A49 |
| bacterial skin diseases | — | D017192 | — |
| escherichia coli infections | EFO_1001318 | D004927 | B96.20 |
| hepatic encephalopathy | — | D006501 | K72.91 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D07: Corticosteroids, dermatological preparations
— D07A: Corticosteroid dermatological preparations, plain
— D07AC: Corticosteroids, potent (group iii)
— D07AC07: Fludroxycortide
— D07C: Corticosteroids, combinations with antibiotics
— D07CC: Corticosteroids, potent, combinations with antibiotics
— D07CC03: Fludroxycortide and antibiotics
HCPCS
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | 1 | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | — | — | 1 | — | — | 1 |
| Peritoneal dialysis | D010530 | — | — | — | — | 1 | — | — | 1 |
| Continuous ambulatory peritoneal dialysis | D010531 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Wasting syndrome | D019282 | — | — | — | 1 | — | — | — | 1 |
| Weight loss | D015431 | — | — | — | 1 | — | — | — | 1 |
| Cachexia | D002100 | — | R64 | — | 1 | — | — | — | 1 |
| Anorexia | D000855 | — | R63.0 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Flurandrenolide |
| INN | fludroxycortide |
| Description | Flurandrenolide is a 21-hydroxy steroid. |
| Classification | Small molecule |
| Drug class | androgens |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 |
Identifiers
| PDB | — |
| CAS-ID | 1524-88-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201012 |
| ChEBI ID | — |
| PubChem CID | 15209 |
| DrugBank | DB00846 |
| UNII ID | 8EUL29XUQT (ChemIDplus, GSRS) |
Target
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Variants
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Financial
Revenue by drug
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Estimated US medical usage
Flurandrenolide
Total medical expenditures per year (USD, in millions)
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Refill frequency
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 383 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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58 adverse events reported
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