Toviaz(fesoterodine)
Fesoterodine, Toviaz (fesoterodine) is a small molecule pharmaceutical. Fesoterodine was first approved as Toviaz on 2007-04-20. It is used to treat urge urinary incontinence in the USA. It has been approved in Europe to treat overactive urinary bladder.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| urogenital diseases | D000091642 |
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
Fesoterodine, Toviaz (discontinued: Fesoterodine)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| fesoterodine fumarate | ANDA | 2024-08-30 |
| toviaz | New Drug Application | 2024-03-04 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| urge urinary incontinence | EFO_0006865 | D053202 | N39.41 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
FESOTERODINE FUMARATE, TOVIAZ, PFIZER | |||
| 2024-12-17 | PED | ||
| 2024-06-17 | I-861 | ||
HCPCS
No data
Clinical
Clinical Trials
77 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | 9 | 4 | 13 | 15 | 14 | 55 |
| Urinary incontinence | D014549 | HP_0000020 | R32 | 2 | 1 | 1 | 3 | 1 | 8 |
| Enuresis | D004775 | — | R32 | — | 1 | 1 | 3 | — | 5 |
| Urge urinary incontinence | D053202 | EFO_0006865 | N39.41 | 1 | — | 1 | 1 | — | 3 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | 1 | — | 1 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | 1 | — | 1 |
| Adenocarcinoma | D000230 | — | — | — | — | — | 1 | — | 1 |
| Urinary bladder neck obstruction | D001748 | EFO_1000840 | N32.0 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syndrome | D013577 | — | — | — | — | 3 | — | — | 3 |
| Neurogenic urinary bladder | D001750 | HP_0000011 | N31 | — | — | 2 | — | — | 2 |
| Nocturia | D053158 | — | R35.1 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Spinal cord injuries | D013119 | EFO_1001919 | — | — | 1 | — | — | — | 1 |
| Autonomic dysreflexia | D020211 | EFO_1001762 | G90.4 | — | 1 | — | — | — | 1 |
| Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | 1 | — | — | — | 1 |
| Stress urinary incontinence | D014550 | HP_0010992 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 4 | — | — | — | — | 4 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | 1 | — | — | — | — | 1 |
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
| Food | D005502 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Iron-deficiency anemia | D018798 | HP_0001891 | D50 | — | — | — | — | 8 | 8 |
| Iron deficiencies | D000090463 | — | — | — | — | — | — | 8 | 8 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 1 | 1 |
| Drug interactions | D004347 | — | — | — | — | — | — | 1 | 1 |
| Urologic diseases | D014570 | — | N39.9 | — | — | — | — | 1 | 1 |
| Urinary bladder diseases | D001745 | — | N32.9 | — | — | — | — | 1 | 1 |
| Deprescriptions | D000069340 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Fesoterodine |
| INN | fesoterodine |
| Description | Fesoterodine is a diarylmethane. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)C(=O)Oc1ccc(CO)cc1[C@H](CCN(C(C)C)C(C)C)c1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 286930-02-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201764 |
| ChEBI ID | — |
| PubChem CID | 6918558 |
| DrugBank | DB06702 |
| UNII ID | 621G617227 (ChemIDplus, GSRS) |
Target
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Variants
No data
Financial
Revenue by drug
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Toviaz – Pfizer
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Estimated US medical usage
Fesoterodine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 704 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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7,691 adverse events reported
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