Therapeutic Area | MeSH |
---|---|
neoplasms | D009369 |
respiratory tract diseases | D012140 |
Tradename | Proper name | Company | Number | Date | Products |
---|---|---|---|---|---|
Imfinzi | durvalumab | AstraZeneca | N-761069 RX | 2017-05-01 | 2 products |
Brand Name | Status | Last Update |
---|---|---|
imfinzi | Biologic Licensing Application | 2025-02-28 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
transitional cell carcinoma | — | D002295 | — |
Expiration | Code | ||
---|---|---|---|
durvalumab, Imfinzi, AstraZeneca UK Ltd | |||
2029-10-21 | Orphan excl. |
Code | Description |
---|---|
J9173 | Injection, durvalumab, 10 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-small-cell lung carcinoma | D002289 | — | — | 20 | 51 | 21 | 2 | 11 | 100 |
Lung neoplasms | D008175 | — | C34.90 | 16 | 54 | 15 | 1 | 4 | 85 |
Neoplasms | D009369 | — | C80 | 22 | 17 | 2 | 1 | — | 38 |
Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Carcinoma | D002277 | — | C80.0 | 19 | 37 | 11 | — | 3 | 62 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 17 | 25 | 3 | — | — | 37 |
Small cell lung carcinoma | D055752 | — | — | 7 | 16 | 6 | — | 4 | 33 |
Squamous cell carcinoma of head and neck | D000077195 | — | — | 13 | 15 | 2 | — | — | 25 |
Squamous cell carcinoma | D002294 | — | — | 13 | 15 | 2 | — | — | 25 |
Urinary bladder neoplasms | D001749 | — | C67 | 6 | 17 | 4 | — | — | 25 |
Hepatocellular carcinoma | D006528 | — | C22.0 | 5 | 11 | 6 | — | 4 | 24 |
Triple negative breast neoplasms | D064726 | — | — | 9 | 13 | 2 | — | — | 21 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 6 | 8 | 6 | — | 2 | 20 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 9 | 12 | 1 | — | — | 18 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Adenocarcinoma | D000230 | — | — | 8 | 20 | — | — | — | 22 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 9 | 15 | — | — | — | 21 |
Colorectal neoplasms | D015179 | — | — | 8 | 10 | — | — | — | 16 |
Cholangiocarcinoma | D018281 | — | C22.1 | — | 10 | — | — | — | 10 |
Esophageal neoplasms | D004938 | — | C15 | 4 | 6 | — | — | — | 8 |
Prostatic neoplasms | D011471 | — | C61 | 2 | 6 | — | — | — | 7 |
Stomach neoplasms | D013274 | EFO_0003897 | C16 | 4 | 5 | — | — | — | 7 |
Melanoma | D008545 | — | — | 5 | 2 | — | — | — | 6 |
Squamous cell neoplasms | D018307 | — | — | 3 | 4 | — | — | — | 6 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 4 | 3 | — | — | — | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
B-cell lymphoma | D016393 | — | — | 2 | — | — | — | — | 2 |
Thyroid neoplasms | D013964 | EFO_0003841 | — | 2 | — | — | — | — | 2 |
Thyroid diseases | D013959 | — | E00-E07 | 2 | — | — | — | — | 2 |
Second primary neoplasms | D016609 | — | — | 1 | — | — | — | — | 1 |
Male breast neoplasms | D018567 | — | — | 1 | — | — | — | — | 1 |
Vaginal neoplasms | D014625 | — | C52 | 1 | — | — | — | — | 1 |
Vulvar neoplasms | D014846 | — | C51 | 1 | — | — | — | — | 1 |
Anaplastic thyroid carcinoma | D065646 | — | — | 1 | — | — | — | — | 1 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
Pharyngeal neoplasms | D010610 | — | C14.0 | 1 | — | — | — | — | 1 |
Drug common name | Durvalumab |
INN | durvalumab |
Description | Durvalumab (human mab) |
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | >5X8M:B|durvalumab heavy chain
EVQLVESGGGLVQPGGSLRLSCAASGFTFSRYWMSWVRQAPGKGLEWVANIKQDGSEKYYVDSVKGRFTISRDNAKNSLY
LQMNSLRAEDTAVYYCAREGGWFGELAFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTHHHHHH
>5X8M:C|durvalumab light chain
EIVLTQSPGTLSLSPGERATLSCRASQRVSSSYLAWYQQKPGQAPRLLIYDASSRATGIPDRFSGSGSGTDFTLTISRLE
PEDFAVYYCQQYGSLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
PDB | 5X8M, 5XJ4 |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL3301587 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB11714 |
UNII ID | 28X28X9OKV (ChemIDplus, GSRS) |