Doxecitine
Doxecitine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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5281 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 350 | 529 | 111 | 5 | 29 | 875 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 56 | 151 | 162 | 123 | 95 | 567 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 113 | 333 | 143 | 10 | 27 | 565 |
| Neoplasms | D009369 | — | C80 | 331 | 201 | 41 | 2 | 13 | 500 |
| Colorectal neoplasms | D015179 | — | — | 113 | 257 | 75 | 13 | 17 | 403 |
| Non-small-cell lung carcinoma | D002289 | — | — | 91 | 216 | 95 | 7 | 10 | 381 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 57 | 149 | 57 | 1 | 7 | 242 |
| Rectal neoplasms | D012004 | — | — | 60 | 143 | 45 | 2 | 15 | 242 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 83 | 139 | 45 | 3 | 3 | 229 |
| Adenocarcinoma | D000230 | — | — | 61 | 136 | 36 | 3 | 3 | 202 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cholangiocarcinoma | D018281 | — | C22.1 | 45 | 108 | 31 | — | 4 | 167 |
| Urinary bladder neoplasms | D001749 | — | C67 | 40 | 109 | 34 | — | 3 | 162 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 42 | 70 | 26 | — | 1 | 121 |
| Triple negative breast neoplasms | D064726 | — | — | 23 | 77 | 32 | — | 1 | 116 |
| Nasopharyngeal carcinoma | D000077274 | — | — | 9 | 45 | 50 | — | 5 | 102 |
| Gallbladder neoplasms | D005706 | EFO_0004606 | C23 | 20 | 47 | 20 | — | 3 | 79 |
| Esophageal neoplasms | D004938 | — | C15 | 31 | 46 | 7 | — | 2 | 73 |
| Sarcoma | D012509 | — | — | 35 | 46 | 6 | — | — | 72 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 36 | 33 | 4 | — | 2 | 65 |
| Leukemia | D007938 | — | C95 | 30 | 33 | 1 | — | 3 | 58 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 6 | 19 | — | — | — | 24 |
| Osteosarcoma | D012516 | — | — | 10 | 14 | — | — | 1 | 22 |
| Multiple myeloma | D009101 | — | C90.0 | 10 | 11 | — | — | — | 17 |
| Melanoma | D008545 | — | — | 16 | 6 | — | — | — | 17 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 10 | 11 | — | — | — | 17 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 9 | 8 | — | — | 1 | 15 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 7 | 9 | — | — | 1 | 15 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 8 | 8 | — | — | — | 14 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 10 | 4 | — | — | 1 | 13 |
| T-cell lymphoma cutaneous | D016410 | — | C84.A | 10 | 3 | — | — | — | 12 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia myeloid chronic atypical bcr-abl negative | D054438 | — | C92.2 | 2 | — | — | — | — | 2 |
| Thrombocytosis | D013922 | — | D75.83 | 2 | — | — | — | — | 2 |
| Refractory anemia | D000753 | — | D46.4 | 2 | — | — | — | — | 2 |
| Penile neoplasms | D010412 | — | C60 | 2 | — | — | — | — | 2 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 2 | — | — | — | — | 2 |
| Lymphoproliferative disorders | D008232 | Orphanet_2442 | D47.9 | 2 | — | — | — | — | 2 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 2 | — | — | — | — | 2 |
| Bone marrow diseases | D001855 | — | — | 1 | — | — | — | — | 1 |
| Polycythemia | D011086 | EFO_0005804 | D75.1 | 1 | — | — | — | — | 1 |
| Precancerous conditions | D011230 | — | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prognosis | D011379 | — | — | — | — | — | — | 2 | 2 |
| Liver failure | D017093 | — | K72.9 | — | — | — | — | 2 | 2 |
| Microbiota | D064307 | — | — | — | — | — | — | 1 | 1 |
| Sclerosing cholangitis | D015209 | EFO_0004268 | K83.01 | — | — | — | — | 1 | 1 |
| Contraception behavior | D003268 | — | — | — | — | — | — | 1 | 1 |
| Acute kidney injury | D058186 | — | N17 | — | — | — | — | 1 | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
| Vaginitis | D014627 | EFO_0005757 | N76 | — | — | — | — | 1 | 1 |
| High-risk pregnancy | D018566 | — | — | — | — | — | — | 1 | 1 |
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Doxecitine |
| INN | doxecitine |
| Description | Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position.
|
| Classification | Small molecule |
| Drug class | H2-receptor antagonists (cimetidine type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 |
Identifiers
| PDB | — |
| CAS-ID | 951-77-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL66115 |
| ChEBI ID | 15698 |
| PubChem CID | 637 |
| DrugBank | DB02594 |
| UNII ID | 0W860991D6 (ChemIDplus, GSRS) |
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Safety
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27 adverse events reported
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