Doxecitine
Doxecitine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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FDA
EMA
Combinations
Kygevvi
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| kygevvi | New Drug Application | 2025-11-10 |
Indications
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Clinical
Clinical Trials
5500 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 360 | 545 | 116 | 5 | 29 | 898 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 115 | 340 | 148 | 10 | 27 | 577 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 57 | 151 | 164 | 125 | 97 | 574 |
| Neoplasms | D009369 | — | C80 | 346 | 214 | 43 | 4 | 13 | 523 |
| Colorectal neoplasms | D015179 | — | — | 119 | 269 | 76 | 13 | 17 | 417 |
| Non-small-cell lung carcinoma | D002289 | — | — | 97 | 223 | 95 | 7 | 10 | 390 |
| Rectal neoplasms | D012004 | — | — | 61 | 153 | 47 | 3 | 16 | 255 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 59 | 156 | 59 | 3 | 7 | 253 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 87 | 146 | 46 | 3 | 3 | 238 |
| Adenocarcinoma | D000230 | — | — | 60 | 132 | 37 | 4 | 3 | 200 |
Show 124 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cholangiocarcinoma | D018281 | — | C22.1 | 48 | 116 | 35 | — | 5 | 180 |
| Urinary bladder neoplasms | D001749 | — | C67 | 41 | 111 | 36 | — | 4 | 168 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 45 | 72 | 30 | — | 1 | 129 |
| Triple negative breast neoplasms | D064726 | — | — | 25 | 81 | 35 | — | 1 | 123 |
| Nasopharyngeal carcinoma | D000077274 | — | — | 9 | 48 | 56 | — | 6 | 112 |
| Gallbladder neoplasms | D005706 | EFO_0004606 | C23 | 20 | 50 | 20 | — | 3 | 82 |
| Esophageal neoplasms | D004938 | — | C15 | 31 | 46 | 8 | — | 2 | 74 |
| Sarcoma | D012509 | — | — | 34 | 45 | 5 | — | — | 70 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 36 | 34 | 4 | — | 2 | 66 |
| Fallopian tube neoplasms | D005185 | — | — | 22 | 28 | 13 | — | — | 58 |
Show 152 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 6 | 19 | — | — | — | 24 |
| Osteosarcoma | D012516 | — | — | 10 | 13 | — | — | 1 | 22 |
| Melanoma | D008545 | — | — | 17 | 8 | — | — | — | 19 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 11 | 11 | — | — | — | 18 |
| Multiple myeloma | D009101 | — | C90.0 | 10 | 11 | — | — | — | 17 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 9 | 8 | — | — | 1 | 15 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 7 | 9 | — | — | 1 | 15 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 8 | 8 | — | — | — | 14 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 10 | 4 | — | — | 1 | 13 |
| T-cell lymphoma cutaneous | D016410 | — | C84.A | 10 | 3 | — | — | — | 12 |
Show 173 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia myeloid chronic atypical bcr-abl negative | D054438 | — | C92.2 | 2 | — | — | — | — | 2 |
| Thrombocytosis | D013922 | — | D75.83 | 2 | — | — | — | — | 2 |
| Refractory anemia | D000753 | — | D46.4 | 2 | — | — | — | — | 2 |
| Cutaneous malignant melanoma | D000096142 | — | — | 2 | — | — | — | — | 2 |
| Penile neoplasms | D010412 | — | C60 | 2 | — | — | — | — | 2 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 2 | — | — | — | — | 2 |
| Lymphoproliferative disorders | D008232 | Orphanet_2442 | D47.9 | 2 | — | — | — | — | 2 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 2 | — | — | — | — | 2 |
| Bone marrow diseases | D001855 | — | — | 1 | — | — | — | — | 1 |
| Polycythemia | D011086 | EFO_0005804 | D75.1 | 1 | — | — | — | — | 1 |
Show 44 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prognosis | D011379 | — | — | — | — | — | — | 2 | 2 |
| Liver failure | D017093 | — | K72.9 | — | — | — | — | 2 | 2 |
| Microbiota | D064307 | — | — | — | — | — | — | 1 | 1 |
| Sclerosing cholangitis | D015209 | EFO_0004268 | K83.01 | — | — | — | — | 1 | 1 |
| Contraception behavior | D003268 | — | — | — | — | — | — | 1 | 1 |
| Acute kidney injury | D058186 | — | N17 | — | — | — | — | 1 | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
| Vaginitis | D014627 | EFO_0005757 | N76 | — | — | — | — | 1 | 1 |
| High-risk pregnancy | D018566 | — | — | — | — | — | — | 1 | 1 |
| Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
Show 16 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Doxecitine |
| INN | doxecitine |
| Description | Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position.
|
| Classification | Small molecule |
| Drug class | H2-receptor antagonists (cimetidine type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 |
Identifiers
| PDB | — |
| CAS-ID | 951-77-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL66115 |
| ChEBI ID | 15698 |
| PubChem CID | 637 |
| DrugBank | DB02594 |
| UNII ID | 0W860991D6 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
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42 adverse events reported
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