Doxecitine
Doxecitine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
126 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 4 | 1 | 1 | 2 | — | 8 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | 3 | 1 | 1 | 1 | — | 6 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 2 | — | — | 1 | — | 3 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | — | — | — | 1 | — | 1 |
| B-cell lymphoma | D016393 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 34 | 35 | 3 | — | 2 | 64 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 29 | 30 | 2 | — | 2 | 54 |
| Myeloid leukemia | D007951 | — | C92 | 27 | 31 | 2 | — | 2 | 54 |
| Myelodysplastic syndromes | D009190 | — | D46 | 19 | 26 | 4 | — | 1 | 42 |
| Preleukemia | D011289 | — | — | 18 | 22 | 3 | — | 1 | 36 |
| Syndrome | D013577 | — | — | 19 | 19 | 2 | — | 1 | 34 |
| Recurrence | D012008 | — | — | 10 | 5 | 1 | — | — | 14 |
| Carcinoma | D002277 | — | C80.0 | 5 | 4 | 1 | — | — | 7 |
| Myelomonocytic leukemia acute | D015479 | — | C92.5 | 1 | 4 | 1 | — | — | 5 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 3 | 1 | — | — | 4 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 14 | 6 | — | — | 2 | 21 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 7 | 6 | — | — | 1 | 12 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 5 | 7 | — | — | 1 | 12 |
| Myelomonocytic leukemia juvenile | D054429 | — | C93.3 | 5 | 7 | — | — | 1 | 12 |
| Myelodysplastic-myeloproliferative diseases | D054437 | — | — | 5 | 4 | — | — | — | 7 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 2 | 4 | — | — | — | 6 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 5 | 1 | — | — | — | 5 |
| Fallopian tube neoplasms | D005185 | — | — | 3 | 2 | — | — | — | 4 |
| Hematologic neoplasms | D019337 | — | — | 3 | 1 | — | — | — | 4 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 2 | 3 | — | — | — | 4 |
Show 45 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 3 | — | — | — | — | 3 |
| Anemia | D000740 | HP_0001903 | D64.9 | 2 | — | — | — | — | 2 |
| Refractory anemia | D000753 | — | — | 2 | — | — | — | — | 2 |
| Plasma cell neoplasms | D054219 | — | — | 2 | — | — | — | — | 2 |
| Plasmacytoma | D010954 | — | C90.3 | 2 | — | — | — | — | 2 |
| Bone marrow diseases | D001855 | — | — | 1 | — | — | — | — | 1 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 1 | — | — | — | — | 1 |
| Osteosarcoma | D012516 | — | — | 1 | — | — | — | — | 1 |
| Ewing sarcoma | D012512 | EFO_0000173 | — | 1 | — | — | — | — | 1 |
| Rhabdomyosarcoma | D012208 | — | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Doxecitine |
| INN | doxecitine |
| Description | Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the C2' position.
|
| Classification | Small molecule |
| Drug class | H2-receptor antagonists (cimetidine type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 |
Identifiers
| PDB | — |
| CAS-ID | 951-77-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL66115 |
| ChEBI ID | 15698 |
| PubChem CID | 637 |
| DrugBank | DB02594 |
| UNII ID | 0W860991D6 (ChemIDplus, GSRS) |
Target
No data
Variants
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Financial
No data
Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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26 adverse events reported
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