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AboutPricing
Drug ReportsDegarelix
Firmagon(degarelix)
Degarelix, Firmagon (degarelix) is a protein pharmaceutical. Degarelix was first approved as Firmagon on 2008-12-24. It is used to treat prostatic neoplasms in the USA. It has been approved in Europe to treat prostatic neoplasms. The pharmaceutical is active against gonadotropin-releasing hormone receptor.
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Financial
Trends
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
urogenital diseasesD000091642
Trade Name
FDA
EMA
Firmagon
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Degarelix acetate
Tradename
Company
Number
Date
Products
FIRMAGONFerring PharmaceuticalsN-022201 RX2008-12-24
2 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
firmagonNew Drug Application2024-01-30
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
prostatic neoplasms—D011471C61
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Degarelix Acetate, Firmagon, Ferring
94150852032-04-27U-1895
106953982032-04-27U-1895
117664682032-04-27U-1978
118263972032-04-27U-1978
95793592029-02-10U-1978
107297392029-02-10U-1978
109738702029-02-10U-1978
ATC Codes
L: Antineoplastic and immunomodulating agents
— L02: Endocrine therapy antineoplastic and immunomodulating agents
— L02B: Hormone antagonists and related agents
— L02BX: Other hormone antagonists and related agents in atc
— L02BX02: Degarelix
HCPCS
Code
Description
J9155
Injection, degarelix, 1 mg
Clinical
Clinical Trials
158 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471—C612202241459
Cardiovascular diseasesD002318EFO_0000319I98—111—3
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AdenocarcinomaD000230———2———2
Prostatic hyperplasiaD011470EFO_0000284N40—2———2
HyperplasiaD006965EFO_0000536——2———2
InfertilityD007246EFO_0000545——1———1
Female infertilityD007247EFO_0008560N97—1———1
HypersensitivityD006967EFO_0003785T78.40—1———1
Lower urinary tract symptomsD059411EFO_0008008——1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.0————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDegarelix
INNdegarelix
Description
Degarelix is a polypeptide.
Classification
Protein
Drug classhormone-release inhibiting peptides
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N[C@H](Cc1cccnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(NC(=O)[C@@H]2CC(=O)NC(=O)N2)cc1)C(=O)N[C@H](Cc1ccc(NC(N)=O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(N)=O
Identifiers
PDB—
CAS-ID214766-78-6
RxCUI—
ChEMBL IDCHEMBL415606
ChEBI ID—
PubChem CID16136245
DrugBankDB06699
UNII IDSX0XJI3A11 (ChemIDplus, GSRS)
Target
Agency Approved
GNRHR
GNRHR
Organism
Homo sapiens
Gene name
GNRHR
Gene synonyms
GRHR
NCBI Gene ID
2798
Protein name
gonadotropin-releasing hormone receptor
Protein synonyms
gnRH receptor, gnRH-R, gonadotropin-releasing hormone (type 1) receptor 1, leutinizing hormone releasing horomone receptor, leutinizing-releasing hormone receptor, luliberin receptor, type I GnRH receptor
Uniprot ID
Q92644
Mouse ortholog
Gnrhr (14715)
gonadotropin-releasing hormone receptor (Q61611)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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4,399 adverse events reported
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