Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
signs and symptoms pathological conditions | D013568 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ANGIOMAX RTU | MAIA Biotechnology | N-211215 RX | 2019-07-25 | 1 products, RLD, RS |
ANGIOMAX | Sandoz | N-020873 RX | 2000-12-15 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
angiomax | New Drug Application | 2019-06-30 |
bivalirudin | ANDA | 2024-12-23 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
unstable angina | EFO_1000985 | D000789 | I20.0 |
Code | Description |
---|---|
J0583 | Injection, bivalirudin, 1 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Thrombosis | D013927 | — | — | — | 1 | 2 | 1 | — | 4 |
Syndrome | D013577 | — | — | — | — | 1 | 1 | 1 | 3 |
Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | — | 2 | 1 | — | 3 |
Coronary artery disease | D003324 | — | I25.1 | — | — | — | 1 | 1 | 2 |
Coronary disease | D003327 | — | — | — | — | — | 1 | — | 1 |
Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 4 | — | — | 4 |
Infarction | D007238 | EFO_0009463 | — | — | — | 4 | — | — | 4 |
Coronary artery bypass | D001026 | EFO_0003776 | — | — | — | 4 | — | — | 4 |
Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | 2 | — | 1 | 3 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 2 | — | — | 2 |
Unstable angina | D000789 | EFO_1000985 | I20.0 | — | — | 1 | — | — | 1 |
Acute disease | D000208 | — | — | — | — | 1 | — | — | 1 |
Inferior wall myocardial infarction | D056989 | EFO_1000983 | — | — | — | 1 | — | — | 1 |
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 1 | — | — | 1 |
Endovascular procedures | D057510 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Stable angina | D060050 | — | I20.89 | — | — | — | — | 1 | 1 |
Drug common name | Bivalirudin |
INN | bivalirudin |
Description | Bivalirudin is a synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant. It has a role as an anticoagulant and an EC 3.4.21.5 (thrombin) inhibitor. |
Classification | Protein |
Drug class | anticoagulants (hirudin type) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)O |
PDB | — |
CAS-ID | 128270-60-0 |
RxCUI | — |
ChEMBL ID | CHEMBL2103749 |
ChEBI ID | 59173 |
PubChem CID | 16129704 |
DrugBank | DB00006 |
UNII ID | TN9BEX005G (ChemIDplus, GSRS) |