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Company ReportsThe Medicines Company

The Medicines Company

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

postoperative pain

venous thrombosis

,

healthy volunteers/patients

,

carotid artery diseases

,

cardiogenic shock

,

congenital heart defects

,

cardiomyopathies

,

,

coronary artery bypass

,

cardiovascular diseases

,

,

,

subarachnoid hemorrhage

,

,

intracranial aneurysm

,

endovascular procedures

,

aortic valve stenosis

,

transcatheter aortic valve replacement

,

hematologic diseases

,

cardiac surgical procedures

,

,

,

myocardial infarction

,

,

coronary artery disease

,

st elevation myocardial infarction

,

acute coronary syndrome

,

coronary disease

,

myocardial ischemia

,

percutaneous coronary intervention

,

,

,

inferior wall myocardial infarction

,

,

,

,

non-st elevated myocardial infarction

,

unstable angina

,

thrombocytopenia

,

hemostatic disorders

,

,

balloon angioplasty coronary

,

respiratory distress syndrome

,

blood coagulation disorders

,

angina pectoris

,

,

,

coronavirus infections

,

,

,

,

,

,

mucocutaneous lymph node syndrome

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

urinary tract infections

,

hyperphosphatemia

,

,

,

sleep initiation and maintenance disorders

,

,

cardiac arrhythmias

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

atherosclerosis

,

carotid stenosis

,

microvascular angina

,

respiratory insufficiency

type 1 diabetes mellitus

,

,

,

,

type 2 diabetes mellitus

,

,

,

,

movement disorders

,

central nervous system diseases

,

,

neurodegenerative diseases

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

drug-induced akathisia

,

nervous system diseases

,

chronic hepatitis

,

parkinsonian disorders

,

drug-induced dyskinesia

,

postoperative pain

,

,

,

postherpetic neuralgia

,

liver cirrhosis

,

,

,

castration-resistant prostatic neoplasms

,

non-small-cell lung carcinoma

,

,

alzheimer disease

,

,

thyroid neoplasms

,

thyroid diseases

,

parkinson disease

,

diabetes mellitus

,

chronic hepatitis c

,

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

small cell lung carcinoma

,

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

rheumatoid arthritis

,

,

polycythemia vera

,

neuromuscular blockade

,

prostatic neoplasms

,

,

,

chronic renal insufficiency

,

acute coronary syndrome

,

kidney diseases

,

,

,

,

uterine prolapse

,

intestinal obstruction

,

,

spinal diseases

,

delayed emergence from anesthesia

,

,

,

muscle relaxation

,

,

,

,

urinary retention

,

,

female infertility

,

uterine diseases

,

postoperative complications

,

,

wound infection

,

surgical wound infection

prostatic hyperplasia

,

healthy volunteers/patients

,

respiratory tract diseases

,

respiration disorders

,

,

kidney diseases

,

,

,

,

,

respiratory tract infections

,

,

premature obstetric labor

,

,

pulmonary edema

,

,

bacterial infections

,

,

hepatic insufficiency

,

,

non-alcoholic fatty liver disease

,

,

multiple myeloma

,

,

,

,

breast neoplasms

,

,

pulmonary tuberculosis

,

atherosclerosis

,

obstructive lung diseases

,

plasma cell neoplasms

,

,

pancreatic neoplasms

,

,

follicular lymphoma

,

allergic rhinitis

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

sjogren's syndrome

,

,

,

,

,

systemic lupus erythematosus

,

,

,

acquired immunodeficiency syndrome

,

,

type 2 diabetes mellitus

,

human influenza

,

communicable diseases

,

,

,

parkinson disease

,

,

migraine disorders

,

,

major depressive disorder

,

depressive disorder

,

churg-strauss syndrome

,

granulomatosis with polyangiitis

,

systemic vasculitis

,

eosinophilic granuloma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

restless legs syndrome

,

psychomotor agitation

,

,

hypereosinophilic syndrome

,

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

urinary tract infections

,

,

respiratory syncytial virus infections

,

,

chronic obstructive pulmonary disease

,

,

diabetes mellitus

,

,

,

,

pulmonary eosinophilia

,

prostatic neoplasms

,

autoimmune diseases

,

,

growth and development

,

,

,

postherpetic neuralgia

,

healthy volunteers/patients

,

factor vii deficiency

,

,

hidradenitis suppurativa

,

chronic kidney failure

,

diabetes mellitus

,

diffuse scleroderma

,

,

systemic scleroderma

,

rheumatoid arthritis

,

chronic obstructive pulmonary disease

,

soft tissue infections

,

necrotizing fasciitis

,

fournier gangrene

,

,

raynaud disease

,

wounds and injuries

,

myasthenia gravis

,

cardiac surgical procedures

,

,

eosinophilic esophagitis

,

postpartum hemorrhage

,

acute kidney injury

,

sickle cell anemia

,

acute chest syndrome

,

vaso-occlusive crises

,

,

agammaglobulinemia

,

common variable immunodeficiency

,

graft vs host disease

,

hereditary angioedemas

,

afibrinogenemia

,

blood coagulation disorders

,

ischemic stroke

,

,

coronary artery disease

,

,

atherosclerosis

,

heart valve diseases

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

kidney transplantation

,

,

von willebrand diseases

,

hemostatic disorders

,

postoperative hemorrhage

,

dermatomyositis

,

atrial fibrillation

,

,

,

cardiovascular diseases

,

acute coronary syndrome

,

hemorrhagic stroke

,

peripheral arterial disease

,

central nervous system diseases

,

central nervous system infections

,

encephalomyelitis

,

,

meningoencephalitis

,

acquired immunodeficiency syndrome

,

,

factor xiii deficiency

,

thrombocytopenia

,

hematologic neoplasms

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

burkitt lymphoma

,

,

primary immunodeficiency diseases

,

,

hereditary angioedema types i and ii

,

alpha 1-antitrypsin deficiency

,

surgical blood loss

,

immunologic deficiency syndromes

,

thrombocytopenic purpura idiopathic

,

,

cardiovascular surgical procedures

,

tropical spastic paraparesis

,

thromboembolism

,

,

pneumococcal infections

,

,

streptococcal infections

,

bacterial pneumonia

,

bacterial meningitis

,

haemophilus influenzae

,

hereditary complement deficiency diseases

,

neisseriaceae infections

,

,

,

,

communicable diseases

,

ataxia telangiectasia

,

,

x-linked combined immunodeficiency diseases

,

cerebellar ataxia

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

rectal neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

stomach neoplasms

,

,

,

ovarian neoplasms

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

b-cell lymphoma

,

,

,

lupus nephritis

,

ductal carcinoma breast

,

macular degeneration

,

,

renal cell carcinoma

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

urinary bladder neoplasms

,

colonic neoplasms

,

,

head and neck neoplasms

,

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

pancreatic neoplasms

,

,

,

,

neoplasms by site

,

breast diseases

,

urologic neoplasms

,

prostatic neoplasms

,

,

follicular lymphoma

,

lymphoid leukemia

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

atypical hemolytic uremic syndrome

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

ovarian epithelial carcinoma

,

brain neoplasms

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

vision disorders

,

,

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

,

endometrioid carcinoma

,

giant cell arteritis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

membranous glomerulonephritis

,

multiple sclerosis

,

chronic progressive multiple sclerosis

,

ankylosing spondylitis

,

spondylarthritis

,

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

bcr-abl positive chronic myelogenous leukemia

,

circulating neoplastic cells

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

,

hemolytic anemia autoimmune

,

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

endometrial neoplasms

,

,

graft rejection

,

retinal neovascularization

,

human influenza

,

type 3 von willebrand disease

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

myocardial infarction

,

st elevation myocardial infarction

,

anterior wall myocardial infarction

,

,

inferior wall myocardial infarction

pancreatic neoplasms

,

stomach neoplasms

,

liver neoplasms

,

colonic neoplasms

,

,

,

,

pancreaticoduodenectomy

,

,

biliary tract surgical procedures

,

,

femoral fractures

Antineoplaston a10

healthy volunteers/patients

,

,

,

allergic rhinitis perennial

P2y purinoceptor 12

st elevation myocardial infarction

,

dual anti-platelet therapy

,

coronary artery disease

,

renal insufficiency

,

ischemic stroke

,

,

coronary disease

,

myocardial ischemia

,

hematologic diseases

,

,

blood coagulation disorders

,

hemorrhagic stroke

,

thrombocytopenia

,

hemostatic disorders

,

coagulation protein disorders

Fluoroquinolone

healthy volunteers/patients

,

kidney diseases

,

retinal diseases

,

,

insulin resistance

,

,

,

urinary tract infections

,

,

respiratory tract infections

,

,

bacterial infections

,

,

chronic bronchitis

,

respiratory tract diseases

,

infectious skin diseases

,

bacterial skin diseases

,

bacterial pneumonia

,

community-acquired pneumonia

,

,

,

bronchial diseases

,

urologic diseases

,

,

,

maxillary sinusitis

,

,

,

healthcare-associated pneumonia

,

congenital abnormalities

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

neurogenic urinary bladder

,

,

paranasal sinus diseases

,

,

,

,

,

,

,

critical illness

,

,

retinal detachment

,

aortic dissection

,

dissociative disorders

,

musculoskeletal diseases

atrial fibrillation

,

dual anti-platelet therapy

,

coronary artery disease

,

myocardial ischemia

,

coronary disease

,

vascular diseases

,

coronary stenosis

,

coronary restenosis

,

myocardial infarction

,

acute coronary syndrome

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