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Company ReportsThe Medicines Company

The Medicines Company

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Clinical Trials

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

postoperative pain

,

spinal injuries

,

hypertriglyceridemia

,

pancreatic neoplasms

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

prostatic neoplasms

,

,

hepatocellular carcinoma

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

inflammatory breast neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

hematopoietic stem cell transplantation

,

bronchiolitis obliterans syndrome

,

,

hyperlipoproteinemia type ii

,

graft vs host disease

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

,

psychology rejection

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

,

juvenile arthritis

,

,

,

hepatitis b virus

,

,

,

pituitary acth hypersecretion

,

,

acute coronary syndrome

,

,

myocardial infarction

,

coronary stenosis

,

atherosclerotic plaque

,

,

,

hypersensitivity

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

atherosclerosis

,

breast neoplasms

,

,

hyperlipidemias

,

cardiovascular diseases

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

,

,

coronary artery disease

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

renal insufficiency

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

neoplasm metastasis

,

metabolic syndrome

,

preconception care

,

drug interactions

,

percutaneous coronary intervention

,

,

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

cytomegalovirus infections

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

falciparum malaria

,

,

ovarian neoplasms

,

renal cell carcinoma

,

colorectal neoplasms

,

,

healthy volunteers/patients

,

,

,

multiple myeloma

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma of head and neck

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

endometrial neoplasms

,

plasma cell neoplasms

,

malignant mesothelioma

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

adenomyoepithelioma

,

,

breast neoplasms

,

rheumatoid arthritis

,

haemophilus influenzae type b

,

haemophilus infections

,

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

,

insulin resistance

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

ductal carcinoma breast

,

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

ischemic stroke

,

,

carotid stenosis

,

pathologic constriction

,

,

intracranial hemorrhages

,

,

,

myocardial infarction

,

,

cardiogenic shock

,

coronary artery disease

,

knee prosthesis

,

,

tendon injuries

,

,

tissue adhesions

,

hip osteoarthritis

,

,

,

,

high-risk pregnancy

,

intervertebral disc degeneration

,

multiple trauma

,

vascular diseases

,

,

neoplasm metastasis

,

operative surgical procedures

,

urinary retention

,

,

,

physician-nurse relations

,

,

,

traumatic intracranial hemorrhage

,

cardiovascular diseases

,

cerebrovascular disorders

,

central nervous system diseases

,

,

nervous system diseases

,

,

,

,

pulmonary emphysema

,

,

spinal curvatures

,

critical illness

,

pituitary neoplasms

,

pituitary diseases

,

hereditary breast and ovarian cancer syndrome

,

spinal cord neoplasms

,

spinal neoplasms

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

squamous cell carcinoma

,

hemoglobinometry

,

,

traumatic brain injuries

,

von willebrand diseases

,

,

,

,

,

,

hematologic neoplasms

,

,

hereditary hemorrhagic telangiectasia

,

,

hemorrhagic shock

,

thrombocytopenia

,

hyperpigmentation

,

transfusion reaction

,

coronary artery bypass

,

,

chronic renal insufficiency

,

,

urinary bladder neoplasms

,

,

traumatic brain hemorrhage

,

pulmonary hypertension

,

lung transplantation

,

spinal dysraphism

,

,

intraoperative complications

,

aortic dissection

,

brain neoplasms

,

,

,

head and neck neoplasms

,

acute kidney injury

,

,

transcatheter aortic valve replacement

,

hereditary angioedemas

,

female genital neoplasms

,

,

accidental injuries

,

,

obstetric labor

,

,

hematopoietic stem cell transplantation

,

,

subarachnoid hemorrhage

,

carotid artery diseases

,

spinal injuries

,

abdominal aortic aneurysm

,

,

aortic aneurysm

,

pathologic processes

,

,

,

pancreatic neoplasms

,

,

femoracetabular impingement

,

,

surgical wound infection

,

,

,

,

agranulocytosis

,

feeding behavior

,

replacement arthroplasty shoulder

,

,

postpartum hemorrhage

,

surgical blood loss

,

postoperative hemorrhage

,

knee osteoarthritis

,

,

,

,

,

,

obstetric labor complications

,

,

postoperative pain

,

replacement arthroplasty knee

,

wounds and injuries

,

,

blood coagulation disorders

,

placenta previa

,

hemostatic disorders

,

gastrointestinal hemorrhage

,

uterine hemorrhage

,

blood transfusion

,

replacement arthroplasty hip

,

cerebral hemorrhage

,

,

drug-related side effects and adverse reactions

,

,

,

subdural hematoma

,

subdural hematoma chronic

,

,

cardiac surgical procedures

,

,

,

,

,

venous thrombosis

,

,

,

femoral fractures

,

postoperative complications

,

,

rotator cuff injuries

,

breast neoplasms

,

cesarean section

,

cardiopulmonary bypass

,

coronary artery disease

,

,

,

,

,

,

thromboembolism

,

,

,

congenital abnormalities

,

congenital heart defects

,

,

anterior cruciate ligament injuries

,

,

,

liver cirrhosis

,

,

ovarian neoplasms

,

uterine myomectomy

,

anterior cruciate ligament reconstruction

,

,

craniosynostoses

,

,

bariatric surgery

,

,

musculoskeletal diseases

,

healthy volunteers/patients

,

,

venous thromboembolism

,

paranasal sinus diseases

,

shoulder impingement syndrome

,

prostatic neoplasms

,

nephrolithiasis

,

,

,

placenta accreta

,

spinal stenosis

,

,

femoral neck fractures

,

intracranial hemorrhages

,

prostatic hyperplasia

,

hypersensitivity

,

,

nasal obstruction

,

,

pathologic dilatation

,

urologic diseases

,

patient satisfaction

,

,

,

,

orthognathic surgery

,

tooth extraction

,

pregnancy complications

,

pelvic organ prolapse

,

hemorrhagic stroke

,

,

,

stomach neoplasms

,

liver neoplasms

,

colonic neoplasms

,

ovarian epithelial carcinoma

,

radius fractures

,

wrist fractures

,

,

humeral fractures

,

,

opioid-related disorders

,

deficiency diseases

,

chronic urticaria

,

,

,

injection site reaction

,

,

cross infection

,

wound infection

,

,

,

,

colorectal neoplasms

,

uterine inertia

,

staghorn calculi

,

myocardial infarction

,

pulmonary embolism

,

,

hemiarthroplasty

,

arteriovenous fistula

,

,

pathologic constriction

,

gynecologic surgical procedures

,

rheumatic diseases

,

,

,

,

,

pancreaticoduodenectomy

,

,

biliary tract surgical procedures

,

,

,

dupuytren contracture

,

,

,

,

esophageal neoplasms

,

duodenal neoplasms

,

heart valve diseases

,

prospective studies

,

randomized controlled trials as topic

,

eyelid diseases

,

,

shoulder fractures

,

shoulder injuries

,

contraceptive devices

,

,

autoimmune diseases

,

intravenous administration

,

,

,

,

,

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

urinary tract infections

,

,

sleep initiation and maintenance disorders

,

cardiac arrhythmias

,

communicable diseases

,

,

,

liver transplantation

,

spinal cord diseases

,

blood platelet disorders

,

,

pigmentation disorders

,

heterotopic ossification

,

coronavirus infections

,

,

mucocutaneous lymph node syndrome

,

hyperphosphatemia

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

,

rheumatoid arthritis

,

replacement arthroplasty

,

kidney diseases

,

respiratory tract infections

,

,

migraine disorders

,

,

,

bacterial infections

,

intraabdominal infections

,

healthcare-associated pneumonia

,

methicillin-resistant staphylococcus aureus

,

,

staphylococcal infections

,

,

,

general anesthesia

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

,

bipolar disorder

,

autistic disorder

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

,

iron-deficiency anemia

,

iron deficiencies

,

diabetes insipidus

,

cytoreduction surgical procedures

,

primary graft dysfunction

,

intervertebral disc displacement

,

,

congenital hip dislocation

,

femur head necrosis

,

,

acute lung injury

,

retinal diseases

,

factor xi deficiency

,

closed fractures

,

orthopedic procedures

,

erythrocyte transfusion

,

neurosurgical procedures

,

lacrimal duct obstruction

,

off-pump coronary artery bypass

,

spinal cord compression

,

hematologic diseases

,

recreational drug use

,

,

peptic ulcer hemorrhage

,

osteogenesis imperfecta

,

skin pigmentation

,

obstetric delivery

,

,

,

obstetrical anesthesia

,

perinatal death

,

abruptio placentae

,

prolonged pregnancy

,

,

transurethral resection of prostate

,

,

vaginal hysterectomy

,

percutaneous nephrolithotomy

,

,

cardiovascular surgical procedures

,

lens subluxation

,

joint dislocations

,

fracture dislocation

,

elbow fractures

,

dermatofibrosarcoma

,

spontaneous fractures

,

thoracic surgical procedures

,

autologous blood transfusion

,

,

,

retinal detachment

,

diabetic retinopathy

,

renal insufficiency

,

,

spinal anesthesia

,

,

ear acupuncture

,

acupuncture analgesia

,

acupuncture therapy

,

,

end stage liver disease

,

allergic rhinitis

,

,

,

,

inherited blood coagulation disorders

Antineoplaston a10

,

breast neoplasms

,

pancreatic neoplasms

,

,

head and neck neoplasms

,

,

,

,

bile duct neoplasms

,

liver neoplasms

,

colonic neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

P2y purinoceptor 12

sickle cell anemia

,

blood flow velocity

,

coronary circulation

,

peripheral arterial disease

,

myocardial infarction

,

,

acute coronary syndrome

,

,

cardiovascular diseases

,

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

migraine disorders

,

healthy volunteers/patients

Fluoroquinolone

healthy volunteers/patients

,

kidney diseases

,

retinal diseases

,

,

insulin resistance

,

,

,

urinary tract infections

,

,

respiratory tract infections

,

,

bacterial infections

,

,

chronic bronchitis

,

respiratory tract diseases

,

infectious skin diseases

,

bacterial skin diseases

,

bacterial pneumonia

,

community-acquired pneumonia

,

,

,

bronchial diseases

,

urologic diseases

,

,

,

maxillary sinusitis

,

,

,

healthcare-associated pneumonia

,

congenital abnormalities

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

neurogenic urinary bladder

,

,

paranasal sinus diseases

,

,

,

,

,

,

,

critical illness

,

,

retinal detachment

,

aortic dissection

,

dissociative disorders

,

musculoskeletal diseases

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