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Company ReportsThe Medicines Company

The Medicines Company

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Clinical Trials

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Angiox	Bivalirudin	2004-09-20	2028-2039	Acute coronary syndrome , Unstable angina
Ionsys	Fentanyl	2006-05-22	2024-2033	Neoplasms , Pain , Postoperative pain , Psychotic disorders

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

paroxysmal dyspnea

,

large b-cell lymphoma diffuse

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

,

sjogren's syndrome

,

,

hodgkin disease

,

mantle-cell lymphoma

,

b-cell lymphoma

,

triple negative breast neoplasms

,

renal cell carcinoma

,

,

,

,

chronic hepatitis b

,

communicable diseases

,

,

patient compliance

,

autoimmune diseases

,

,

parkinson disease

,

parkinsonian disorders

,

movement disorders

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

chronic renal insufficiency

,

,

pituitary acth hypersecretion

,

,

type 1 diabetes mellitus

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

brain neoplasms

,

,

oligodendroglioma

,

pancreatic neoplasms

,

,

neuroendocrine tumors

,

islet cell carcinoma

,

,

,

somatostatinoma

,

,

,

breast neoplasms

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

retinal vein occlusion

,

vision disorders

,

macular degeneration

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

graft vs host disease

,

juvenile arthritis

,

kidney diseases

,

left ventricular dysfunction

,

st elevation myocardial infarction

,

non-st elevated myocardial infarction

,

inferior wall myocardial infarction

,

,

,

organ transplantation

,

wet macular degeneration

,

neoplasm metastasis

,

,

graft rejection

,

,

obstructive lung diseases

,

,

non-alcoholic fatty liver disease

,

,

postoperative pain

,

,

choroidal neovascularization

,

chronic kidney failure

,

liver transplantation

,

kidney transplantation

,

renal insufficiency

,

chronic obstructive pulmonary disease

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

liver cirrhosis

,

,

atrial fibrillation

,

bipolar disorder

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

,

falciparum malaria

,

streptococcal infections

,

human influenza

,

,

,

acquired immunodeficiency syndrome

,

migraine disorders

,

,

gastrointestinal diseases

,

cystic fibrosis

,

digestive system diseases

,

pancreatic diseases

,

exocrine pancreatic insufficiency

hematologic neoplasms

,

biphenotypic leukemia acute

,

b-cell leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

myelodysplastic syndromes

,

,

muscle spasticity

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

pancreatic ductal carcinoma

,

biliary tract neoplasms

,

esophageal squamous cell carcinoma

,

ovarian neoplasms

,

,

b-cell lymphoma

,

b-cell lymphoma marginal zone

,

fallopian tube neoplasms

,

burkitt lymphoma

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

multiple myeloma

,

prostatic neoplasms

,

pancreatic neoplasms

,

esophageal neoplasms

,

breast neoplasms

,

reactive arthritis

,

waldenstrom macroglobulinemia

,

lymphoproliferative disorders

,

lymphatic diseases

,

intestinal neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

,

,

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

,

primary myelofibrosis

,

,

hairy cell leukemia

,

abdominal hernia

,

,

urinary bladder neoplasms

,

uterine neoplasms

,

knee osteoarthritis

,

residual neoplasm

,

,

interstitial cystitis

,

neoadjuvant therapy

,

ovarian epithelial carcinoma

,

mantle-cell lymphoma

,

female genital neoplasms

,

peritoneal neoplasms

,

fallopian tube diseases

,

,

non-hodgkin lymphoma

,

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

myeloid leukemia acute

,

colorectal neoplasms

,

,

large b-cell lymphoma diffuse

,

follicular lymphoma

,

,

,

musculoskeletal diseases

,

ankylosing spondylitis

,

small cell lung carcinoma

,

macular degeneration

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

inflammatory bowel diseases

,

,

juvenile arthritis

,

neoplasm metastasis

,

,

papulosquamous skin diseases

,

wet macular degeneration

,

hepatocellular carcinoma

,

liver neoplasms

,

,

communicable diseases

,

bacterial infections

,

methicillin-resistant staphylococcus aureus

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

disease progression

,

,

parkinson disease

,

bronchopulmonary dysplasia

,

respiratory syncytial viruses

,

,

,

pyoderma gangrenosum

,

spondylarthropathies

,

spondylarthritis

,

spinal diseases

,

,

intermediate uveitis

,

posterior uveitis

,

precocious puberty

,

migraine disorders

,

retinal diseases

,

retinal degeneration

,

,

choroidal neovascularization

,

,

lymphoid leukemia

,

thyroid diseases

,

,

rheumatoid arthritis

,

,

,

ulcerative colitis

,

psoriatic arthritis

,

hidradenitis suppurativa

,

,

chronic hepatitis c

,

axial spondyloarthritis

,

cardiovascular diseases

,

connective tissue diseases

,

,

,

,

drug monitoring

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

breast neoplasms

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

non-small-cell lung carcinoma

,

neoplasm metastasis

,

myofascial pain syndromes

,

,

,

,

port-wine stain

,

capillary hemangioma

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

healthy volunteers/patients

acute coronary syndrome

,

,

knee prosthesis

,

,

tendon injuries

,

,

tissue adhesions

,

hip osteoarthritis

,

,

,

,

high-risk pregnancy

,

intervertebral disc degeneration

,

multiple trauma

,

vascular diseases

,

,

neoplasm metastasis

,

operative surgical procedures

,

urinary retention

,

,

,

physician-nurse relations

,

,

,

traumatic intracranial hemorrhage

,

cardiovascular diseases

,

cerebrovascular disorders

,

central nervous system diseases

,

,

nervous system diseases

,

,

,

,

pulmonary emphysema

,

,

spinal curvatures

,

critical illness

,

pituitary neoplasms

,

pituitary diseases

,

hereditary breast and ovarian cancer syndrome

,

spinal cord neoplasms

,

spinal neoplasms

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

squamous cell carcinoma

,

hemoglobinometry

,

,

traumatic brain injuries

,

,

von willebrand diseases

,

,

hyperpigmentation

,

,

,

,

hematologic neoplasms

,

,

pulmonary hypertension

,

hereditary hemorrhagic telangiectasia

,

,

hemorrhagic shock

,

thrombocytopenia

,

transfusion reaction

,

coronary artery bypass

,

,

chronic renal insufficiency

,

,

urinary bladder neoplasms

,

accidental injuries

,

,

iron deficiencies

,

traumatic brain hemorrhage

,

lung transplantation

,

spinal dysraphism

,

,

intraoperative complications

,

aortic dissection

,

brain neoplasms

,

,

,

head and neck neoplasms

,

acute kidney injury

,

,

transcatheter aortic valve replacement

,

hereditary angioedemas

,

female genital neoplasms

,

,

,

obstetric labor

,

,

hematopoietic stem cell transplantation

,

,

subarachnoid hemorrhage

,

carotid artery diseases

,

spinal injuries

,

abdominal aortic aneurysm

,

,

aortic aneurysm

,

pathologic processes

,

,

,

pancreatic neoplasms

,

,

femoracetabular impingement

,

,

surgical wound infection

,

,

,

,

agranulocytosis

,

feeding behavior

,

replacement arthroplasty shoulder

,

,

,

,

,

surgical blood loss

,

postpartum hemorrhage

,

postoperative hemorrhage

,

,

knee osteoarthritis

,

,

,

,

,

obstetric labor complications

,

replacement arthroplasty knee

,

postoperative pain

,

,

wounds and injuries

,

,

placenta previa

,

hemostatic disorders

,

blood coagulation disorders

,

gastrointestinal hemorrhage

,

uterine hemorrhage

,

replacement arthroplasty hip

,

blood transfusion

,

cerebral hemorrhage

,

,

drug-related side effects and adverse reactions

,

,

cardiac surgical procedures

,

,

subdural hematoma

,

subdural hematoma chronic

,

,

rotator cuff injuries

,

,

,

,

femoral fractures

,

,

,

venous thrombosis

,

,

cesarean section

,

coronary artery disease

,

,

,

postoperative complications

,

breast neoplasms

,

thromboembolism

,

cardiopulmonary bypass

,

,

,

,

,

,

,

congenital heart defects

,

healthy volunteers/patients

,

,

anterior cruciate ligament injuries

,

,

,

liver cirrhosis

,

,

nephrolithiasis

,

,

ovarian neoplasms

,

uterine myomectomy

,

anterior cruciate ligament reconstruction

,

,

femoral neck fractures

,

craniosynostoses

,

bariatric surgery

,

,

musculoskeletal diseases

,

congenital abnormalities

,

,

venous thromboembolism

,

paranasal sinus diseases

,

shoulder impingement syndrome

,

prostatic neoplasms

,

,

placenta accreta

,

spinal stenosis

,

,

intracranial hemorrhages

,

stomach neoplasms

,

,

prostatic hyperplasia

,

hypersensitivity

,

,

nasal obstruction

,

,

pathologic dilatation

,

urologic diseases

,

patient satisfaction

,

,

,

,

orthognathic surgery

,

tooth extraction

,

pregnancy complications

,

pelvic organ prolapse

,

hemorrhagic stroke

,

,

,

liver neoplasms

,

colonic neoplasms

,

ovarian epithelial carcinoma

,

radius fractures

,

wrist fractures

,

,

humeral fractures

,

percutaneous nephrolithotomy

,

,

,

opioid-related disorders

,

,

deficiency diseases

,

chronic urticaria

,

,

,

injection site reaction

,

,

cross infection

,

wound infection

,

,

,

,

colorectal neoplasms

,

uterine inertia

,

staghorn calculi

,

myocardial infarction

,

pulmonary embolism

,

,

hemiarthroplasty

,

arteriovenous fistula

,

,

pathologic constriction

,

gynecologic surgical procedures

,

rheumatic diseases

,

,

,

,

,

pancreaticoduodenectomy

,

,

biliary tract surgical procedures

,

,

,

dupuytren contracture

,

,

,

,

esophageal neoplasms

,

duodenal neoplasms

,

heart valve diseases

,

prospective studies

,

randomized controlled trials as topic

,

eyelid diseases

,

,

shoulder fractures

,

shoulder injuries

,

contraceptive devices

,

,

,

autoimmune diseases

,

intravenous administration

,

,

urethral stricture

,

urethral diseases

,

,

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

urinary tract infections

,

,

sleep initiation and maintenance disorders

,

cardiac arrhythmias

,

,

,

liver transplantation

,

spinal cord diseases

,

blood platelet disorders

,

,

pigmentation disorders

,

heterotopic ossification

,

coronavirus infections

,

,

mucocutaneous lymph node syndrome

,

hyperphosphatemia

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

,

coagulation protein disorders

,

attention deficit disorder with hyperactivity

,

,

rheumatoid arthritis

,

replacement arthroplasty

,

kidney diseases

,

respiratory tract infections

,

,

,

migraine disorders

,

,

,

communicable diseases

,

bacterial infections

,

intraabdominal infections

,

healthcare-associated pneumonia

,

methicillin-resistant staphylococcus aureus

,

,

staphylococcal infections

,

,

,

general anesthesia

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

,

bipolar disorder

,

autistic disorder

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

,

iron-deficiency anemia

,

diabetes insipidus

,

cytoreduction surgical procedures

,

primary graft dysfunction

,

intervertebral disc displacement

,

,

congenital hip dislocation

,

femur head necrosis

,

,

acute lung injury

,

retinal diseases

,

factor xi deficiency

,

closed fractures

,

orthopedic procedures

,

erythrocyte transfusion

,

neurosurgical procedures

,

lacrimal duct obstruction

,

off-pump coronary artery bypass

,

spinal cord compression

,

hematologic diseases

,

recreational drug use

,

,

peptic ulcer hemorrhage

,

osteogenesis imperfecta

,

skin pigmentation

,

obstetric delivery

,

,

,

obstetrical anesthesia

,

perinatal death

,

abruptio placentae

,

prolonged pregnancy

,

,

transurethral resection of prostate

,

,

vaginal hysterectomy

,

,

cardiovascular surgical procedures

,

lens subluxation

,

joint dislocations

,

fracture dislocation

,

elbow fractures

,

dermatofibrosarcoma

,

spontaneous fractures

,

thoracic surgical procedures

,

autologous blood transfusion

,

,

,

retinal detachment

,

diabetic retinopathy

,

renal insufficiency

,

,

spinal anesthesia

,

,

ear acupuncture

,

acupuncture analgesia

,

acupuncture therapy

,

,

end stage liver disease

,

allergic rhinitis

,

,

,

,

inherited blood coagulation disorders

,

tibial fractures

,

Antineoplaston a10

breast neoplasms

,

,

,

triple negative breast neoplasms

P2y purinoceptor 12

blood flow velocity

,

coronary circulation

,

pathologic processes

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

ischemic stroke

,

,

,

kidney diseases

,

sickle cell anemia

,

,

respiratory tract infections

,

respiratory tract diseases

,

,

human influenza

,

community-acquired pneumonia

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

graft rejection

,

cerebral infarction

,

coronary artery disease

,

acute coronary syndrome

,

myocardial infarction

,

,

coronary disease

,

myocardial ischemia

,

,

percutaneous coronary intervention

,

st elevation myocardial infarction

,

,

platelet aggregation

,

atrial fibrillation

,

cardiovascular diseases

,

,

unstable angina

,

dual anti-platelet therapy

,

,

inferior wall myocardial infarction

,

peripheral arterial disease

,

non-st elevated myocardial infarction

,

,

intracranial aneurysm

,

atherosclerosis

,

drug-eluting stents

,

,

coronary stenosis

,

healthy volunteers/patients

,

chronic renal insufficiency

,

,

,

endovascular procedures

,

peripheral vascular diseases

,

,

drug interactions

,

arteriosclerosis

,

,

,

cardiogenic shock

,

vascular diseases

,

ventricular remodeling

,

,

,

aortic valve stenosis

,

,

angina pectoris

,

platelet activation

,

platelet function tests

,

,

induced hypothermia

,

stomatognathic diseases

,

,

out-of-hospital cardiac arrest

,

migraine disorders

,

,

type 2 diabetes mellitus

,

,

thrombocytopenia

,

renal insufficiency

,

hematologic diseases

,

,

blood coagulation disorders

,

hemorrhagic stroke

,

hemostatic disorders

,

coagulation protein disorders

,

heart valve prosthesis

,

cerebral hemorrhage

,

subarachnoid hemorrhage

,

,

nervous system diseases

,

coronary thrombosis

,

drug resistance

,

,

disseminated intravascular coagulation

,

heart disease risk factors

,

,

systemic inflammatory response syndrome

,

,

postoperative hemorrhage

,

surgical blood loss

,

,

,

,

endomyocardial fibrosis

,

cerebrovascular disorders

,

stomach neoplasms

,

blood transfusion

,

extracorporeal membrane oxygenation

,

drug-related side effects and adverse reactions

,

pharmacogenomic testing

,

,

cardiomyopathies

,

,

intracranial arteriosclerosis

,

diabetes mellitus

,

arterial occlusive diseases

,

surgical amputation

,

essential thrombocythemia

healthy volunteers/patients

,

Fluoroquinolone

healthy volunteers/patients

,

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