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Drug ReportsArticaine
Articaine
Orabloc, Septocaine (articaine) is a small molecule pharmaceutical. Articaine was first approved as Septocaine on 2000-04-03. It is used to treat pain in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
Combinations
Orabloc, Septocaine (discontinued: Articaine epinephrine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Articaine hydrochloride
+
Epinephrine bitartrate
Tradename
Company
Number
Date
Products
SEPTOCAINEDeprocoN-020971 RX2000-04-03
2 products, RLD, RS
ORABLOCPierrelN-022466 RX2010-02-26
2 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
articadentNDA authorized generic2024-03-01
articaineNDA authorized generic2024-03-06
articaine hcl and epinephrineNDA authorized generic2023-01-14
articaine hydrochloride and epinephrineNDA authorized generic2024-11-18
articaine hydrochloride and epinephrine bitartrateNew Drug Application2010-08-23
orablocNew Drug Application2018-11-22
septocaine2006-12-26
septocaine and epinephrineNew Drug Application2024-10-23
ultacan ultacan forteANDA2017-07-20
zorcaineNDA authorized generic2024-03-06
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
septic shockD012772A48.3
hypotensionEFO_0005251D007022I95
painEFO_0003843D010146R52
ventricular tachycardiaD017180I47.2
anaphylaxisD000707T88.6
bradycardiaHP_0001662D001919R00.1
heart arrestEFO_0009492D006323I46
open-angle glaucomaEFO_0004190D005902H40.1
heart blockD006327I45.89
airway obstructionD000402
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N01: Anesthetics
N01B: Local anesthetics
N01BB: Amide local anesthetics
N01BB08: Articaine
N01BB58: Articaine, combinations
HCPCS
No data
Clinical
No data
Drug
General
Drug common nameArticaine
INNarticaine
Description
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester is a thiophenecarboxylic acid.
Classification
Small molecule
Drug classlocal anesthetics
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCCNC(C)C(=O)Nc1c(C)csc1C(=O)OC
Identifiers
PDB
CAS-ID23964-58-1
RxCUI
ChEMBL IDCHEMBL1093
ChEBI ID
PubChem CID32170
DrugBankDB09009
UNII IDD3SQ406G9X (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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