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AboutPricing
Drug ReportsArtemether
Artemether
Coartem (artemether) is a small molecule pharmaceutical. Artemether was first approved as Coartem on 2009-04-07. It is used to treat falciparum malaria and malaria in the USA.
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5D
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YTD
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2Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
Combinations
Coartem
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Artemether
+
Lumefantrine
Tradename
Company
Number
Date
Products
COARTEMNovartisN-022268 RX2009-04-07
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
coartemNew Drug Application2024-11-11
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
malariaEFO_0001068D008288B54
falciparum malariaEFO_0007444D016778B50
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P01: Antiprotozoals
— P01B: Antimalarials
— P01BE: Artemisinin and derivatives, plain
— P01BE02: Artemether
— P01BF: Artemisinin and derivatives, combinations
— P01BF01: Artemether and lumefantrine
HCPCS
No data
Clinical
Clinical Trials
238 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MalariaD008288EFO_0001068B54—754115
Falciparum malariaD016778EFO_0007444B50—753—13
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Body weightD001835EFO_0004338——12——2
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameArtemether
INNartemether
Description
Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial. It is a sesquiterpenoid, a cyclic acetal, an organic peroxide, an artemisinin derivative and a semisynthetic derivative.
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Classification
Small molecule
Drug classantimalarials (artemisin derivatives)
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Structure (InChI/SMILES or Protein Sequence)
CO[C@H]1O[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]([C@H]1C)[C@]42OO3
Identifiers
PDB—
CAS-ID71963-77-4
RxCUI—
ChEMBL IDCHEMBL566534
ChEBI ID195280
PubChem CID68911
DrugBankDB06697
UNII IDC7D6T3H22J (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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342 adverse events reported
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