Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Chronic renal insufficiency | D051436 | — | N18 | — | — | 1 | 2 | 1 | 4 |
Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | 1 | 2 | 1 | 4 |
Hyperparathyroidism | D006961 | EFO_0008506 | E21.3 | — | — | 1 | 2 | — | 3 |
Secondary hyperparathyroidism | D006962 | EFO_1001173 | — | — | — | 1 | 2 | — | 3 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | — | 1 | — | 1 |
Renal dialysis | D006435 | EFO_0010690 | Z99.2 | — | — | — | 1 | — | 1 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | — | 1 | — | 1 |
Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | 1 | — | 1 |
Joint diseases | D007592 | — | M12.9 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | 1 | — | — | 1 |
Coronary disease | D003327 | — | — | — | — | 1 | — | — | 1 |
Coronary artery disease | D003324 | — | I25.1 | — | — | 1 | — | — | 1 |
Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 1 | — | — | 1 |
Inflammation | D007249 | MP_0001845 | — | — | — | 1 | — | — | 1 |
Rickets | D012279 | EFO_0005583 | E55.0 | — | — | 1 | — | — | 1 |
Avitaminosis | D001361 | EFO_0005878 | E56.9 | — | — | 1 | — | — | 1 |
Lactation | D007774 | — | — | — | — | 1 | — | — | 1 |
Drug common name | Alfacalcidol |
INN | alfacalcidol |
Description | Alfacalcidol is a member of the class of D3 vitamins that is calciol in which the hydrogen at the 1alpha position is replaced by a hydroxy group. It is an active metabolite of cholecalciferol, which performs important functions in regulation of the calcium balance and the bone metabolism. It has a role as a bone density conservation agent. It is a member of D3 vitamins, a seco-cholestane, a hydroxycalciol and a diol. It is functionally related to a calciol. |
Classification | Small molecule |
Drug class | vitamin D analogs |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C=C1/C(=C\C=C2/CCC[C@@]3(C)[C@H]2CC[C@@H]3[C@H](C)CCCC(C)C)C[C@@H](O)C[C@@H]1O |
PDB | — |
CAS-ID | 41294-56-8 |
RxCUI | — |
ChEMBL ID | CHEMBL1601669 |
ChEBI ID | 31186 |
PubChem CID | 5282181 |
DrugBank | DB01436 |
UNII ID | URQ2517572 (ChemIDplus, GSRS) |