Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertension | D006973 | EFO_0000537 | I10 | 2 | 2 | 1 | — | — | 4 |
Ocular hypertension | D009798 | EFO_1001069 | H40.0 | 2 | 2 | 1 | — | — | 4 |
Glaucoma | D005901 | EFO_0000516 | H40 | 2 | 2 | 1 | — | — | 4 |
Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | 2 | 2 | 1 | — | — | 4 |
Breast density | D000071060 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 6 | — | — | 1 | 7 |
Carcinoma | D002277 | — | C80.0 | — | 4 | — | — | — | 4 |
Carcinoma in situ | D002278 | — | D09.9 | — | 4 | — | — | — | 4 |
Breast carcinoma in situ | D000071960 | — | D05 | — | 4 | — | — | — | 4 |
Ductal carcinoma breast | D018270 | — | — | — | 3 | — | — | — | 3 |
Intraductal carcinoma noninfiltrating | D002285 | — | D05.1 | — | 3 | — | — | — | 3 |
Neoplasms | D009369 | — | C80 | — | 2 | — | — | — | 2 |
Adenocarcinoma | D000230 | — | — | — | 1 | — | — | — | 1 |
Lobular carcinoma | D018275 | EFO_0000570 | — | — | 1 | — | — | — | 1 |
Hyperplasia | D006965 | EFO_0000536 | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Dental caries | D003731 | EFO_0003819 | K02 | — | — | — | — | 1 | 1 |
Feeding behavior | D005247 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Afimoxifene |
INN | afimoxifene |
Description | Afimoxifene is a tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen. It has a role as an antineoplastic agent, an estrogen receptor antagonist and a metabolite. It is a tertiary amino compound and a member of phenols. It is functionally related to a tamoxifen. |
Classification | Small molecule |
Drug class | antiestrogens of the clomifene and tamoxifen groups |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 |
PDB | — |
CAS-ID | 68392-35-8 |
RxCUI | — |
ChEMBL ID | CHEMBL489 |
ChEBI ID | 44616 |
PubChem CID | 449459 |
DrugBank | — |
UNII ID | 17197F0KYM (ChemIDplus, GSRS) |