Ademetionine
Ademetionine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug
General
| Drug common name | Ademetionine |
| INN | ademetionine |
| Description | S-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[S+](CC[C@H](N)C(=O)[O-])C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O |
Identifiers
| PDB | — |
| CAS-ID | 29908-03-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1088977 |
| ChEBI ID | 67040 |
| PubChem CID | 9865604 |
| DrugBank | — |
| UNII ID | 7LP2MPO46S (ChemIDplus, GSRS) |
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Safety
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Adverse Events
0 adverse events reported
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