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Company ReportsSage Therapeutics

Sage Therapeutics(SAGE)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Apomorphine	Apomorphine	2022-02-23	2023-2036	Parkinson disease , Erectile dysfunction
Chlorhexidine	Chlorhexidine	2005-04-25	2024-2027	Periodontal diseases , Infectious skin diseases , Gram-negative bacterial infections , Oral candidiasis , Gram-positive bacterial infections , Hypercholesterolemia , Coronary artery disease , Hypertriglyceridemia , Hyperlipoproteinemias
Zulresso	Brexanolone	2019-06-17	2029-2037	Postpartum depression

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

cognitive dysfunction

,

,

psychotic disorders

,

mental disorders

,

parkinson disease

,

alzheimer disease

,

,

traumatic brain injuries

,

,

,

,

premenstrual syndrome

,

major depressive disorder

,

wounds and injuries

,

healthy volunteers/patients

,

alcohol drinking

,

,

fragile x syndrome

,

cerebellar ataxia

,

neurodegenerative diseases

,

migraine disorders

,

essential tremor

,

,

,

post-traumatic epilepsy

,

complex partial epilepsy

,

tourette syndrome

,

,

,

,

status epilepticus

,

,

respiratory distress syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

depressive disorder

,

postpartum depression

,

post-traumatic stress disorders

,

premenstrual dysphoric disorder

,

traumatic stress disorders

,

,

treatment-resistant depressive disorder

,

smoking cessation

Chlorhexidine gluconate

,

healthy volunteers/patients

,

catheterization

,

communicable diseases

,

,

,

tissue adhesions

,

ventilator-associated pneumonia

,

wounds and injuries

,

stomatognathic diseases

,

,

,

,

,

,

,

,

cerebral hemorrhage

,

pulmonary hypertension

,

pulmonary heart disease

,

diabetic angiopathies

,

retinal vein occlusion

,

macular degeneration

,

diabetic retinopathy

,

gram-positive bacterial infections

,

dentist-patient relations

,

,

,

spinal cord injuries

,

,

bone regeneration

,

premature birth

,

mouth neoplasms

,

,

drug-related side effects and adverse reactions

,

coronavirus infections

,

,

cesarean section

,

cystic fibrosis

,

,

hematologic diseases

,

,

,

,

chronic obstructive pulmonary disease

,

,

,

intractable pain

,

,

,

metabolic bone diseases

,

oropharyngeal neoplasms

,

clostridium infections

,

migraine disorders

,

lysosomal storage diseases

,

,

,

penile prosthesis

,

preoperative care

,

long term adverse effects

,

,

thrombocytopenia

,

,

,

,

vulvovaginal candidiasis

,

non-small-cell lung carcinoma

,

squamous cell carcinoma of head and neck

,

,

,

,

dental pulp necrosis

,

,

neonatal sepsis

,

head and neck neoplasms

,

infant mortality

,

,

periapical periodontitis

,

gingival hemorrhage

,

,

,

,

esophageal neoplasms

,

,

deglutition disorders

,

aphthous stomatitis

,

female genital diseases

,

,

patient compliance

,

,

,

,

radiodermatitis

,

,

acanthamoeba keratitis

,

,

dental calculus

,

,

pathologic processes

,

pelvic organ prolapse

,

obstetric labor complications

,

dental pulp diseases

,

,

,

,

,

erectile dysfunction

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

eyelid neoplasms

,

immunologic cytotoxicity

,

neurofibromatosis 1

,

neurofibromatoses

,

,

periodontal index

,

intraoperative complications

,

neurodevelopmental disorders

,

urinary incontinence

,

pelvic floor disorders

,

taste perception

,

periapical abscess

,

,

,

vaginal discharge

,

puerperal infection

,

newborn infant diseases

,

,

,

communicable diseases

,

,

surgical wound infection

,

,

periodontal diseases

,

,

,

,

ventilator-associated pneumonia

,

,

staphylococcal infections

,

wound infection

,

peri-implantitis

,

chronic periodontitis

,

wounds and injuries

,

cross infection

,

catheter-related infections

,

,

postoperative pain

,

,

,

methicillin-resistant staphylococcus aureus

,

coronary artery disease

,

staphylococcus aureus

,

,

,

bacterial infections

,

postoperative complications

,

breast neoplasms

,

,

diabetes mellitus

,

type 2 diabetes mellitus

,

,

healthy volunteers/patients

,

,

periodontal pocket

,

,

,

,

dental implants

,

urinary tract infections

,

respiratory tract infections

,

gingival recession

,

infectious skin diseases

,

,

,

,

,

,

,

gingival diseases

,

coronary disease

,

myocardial ischemia

,

staphylococcal skin infections

,

chronic kidney failure

,

,

,

soft tissue infections

,

healthcare-associated pneumonia

,

,

,

,

cardiovascular diseases

,

knee osteoarthritis

,

,

propionibacterium acnes

,

,

,

,

tooth discoloration

,

replacement arthroplasty knee

,

,

,

,

,

critical illness

,

,

dental implantation

,

coronary stenosis

,

catheterization

,

,

,

,

,

orthopedic procedures

,

,

,

asymptomatic infections

,

,

opioid-related disorders

,

,

foot dermatoses

,

clostridioides difficile

,

cardiac arrhythmias

,

replacement arthroplasty hip

,

,

epidural analgesia

,

,

myocardial stunning

,

,

surgical amputation

,

,

chronic hepatitis b

,

myocardial infarction

,

,

,

microbial drug resistance

,

peritoneal dialysis

,

,

intravenous substance abuse

,

oral lichen planus

,

,

postoperative hemorrhage

,

acute necrotizing pancreatitis

,

pathologic complete response

,

pseudomonas infections

,

pseudomonas aeruginosa

,

,

postoperative nausea and vomiting

,

,

,

,

hospitalization

,

,

gynecologic surgical procedures

,

aggressive periodontitis

,

,

,

,

liver neoplasms

,

papillomavirus infections

,

human influenza

,

,

,

,

dental pulp capping

,

aspiration pneumonia

,

systemic inflammatory response syndrome

,

skin irritancy tests

,

local anesthesia

,

atopic dermatitis

,

,

post-dural puncture headache

,

operative surgical procedures

,

,

,

,

,

,

alveolar bone loss

,

,

conduction anesthesia

,

vascular diseases

,

congenital abnormalities

,

,

,

bisphosphonate-associated osteonecrosis of the jaw

,

,

cognitive dysfunction

,

prostatic neoplasms

,

multiple drug resistance

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

,

kidney diseases

,

,

airway obstruction

,

tooth demineralization

,

intratracheal intubation

,

central venous catheters

,

,

respiratory insufficiency

,

,

,

hydrogen-ion concentration

,

,

,

,

,

,

,

,

,

,

type 1 diabetes mellitus

,

plantar fasciitis

,

,

inflammatory bowel diseases

,

,

acute lung injury

,

colonic neoplasms

,

chronic renal insufficiency

,

carcinoma in situ

,

,

,

diabetes complications

,

diabetic neuropathies

,

postpartum hemorrhage

,

,

actinic keratosis

,

,

,

peripheral catheterization

,

,

oral candidiasis

,

risk reduction behavior

,

atrial fibrillation

,

gingival overgrowth

,

pigmentation disorders

,

spinal anesthesia

,

epidural anesthesia

,

,

coronary occlusion

,

coronary restenosis

,

,

,

obstructive lung diseases

,

prosthesis-related infections

,

cardiogenic shock

,

bacterial vaginosis

,

reflex sympathetic dystrophy

,

temporomandibular joint disorders

,

,

,

periodontal attachment loss

,

somatoform disorders

,

,

,

,

metabolic syndrome

,

,

venous insufficiency

,

nervous system neoplasms

,

edentulous jaw partially

,

,

photochemotherapy

,

,

granulomatous mastitis

,

,

,

acute coronary syndrome

,

arteriosclerosis

,

arterial occlusive diseases

,

patient participation

,

pain perception

,

percutaneous coronary intervention

,

atherosclerosis

,

atrophic vaginitis

,

,

bundle-branch block

,

benign familial pemphigus

,

brain neoplasms

,

musculoskeletal diseases

,

digestive system diseases

,

pancreatic diseases

,

,

liver cirrhosis

,

male breast neoplasms

,

breast carcinoma in situ

,

breast cancer lymphedema

,

,

,

,

,

child development

,

health behavior

,

,

substance-related disorders

,

,

,

marijuana abuse

,

,

,

major depressive disorder

,

depressive disorder

,

,

,

osteoradionecrosis

,

,

basal cell carcinoma

,

,

squamous cell carcinoma

,

hutchinson's melanotic freckle

,

squamous cell neoplasms

,

,

dysplastic nevus syndrome

,

basal cell neoplasms

,

seborrheic keratosis

,

streptococcus mutans

,

premature rupture fetal membranes

,

,

segmental mastectomy

,

streptococcus milleri group

,

,

,

breast milk expression

,

feeding behavior

,

body composition

,

,

periapical diseases

,

severe acute respiratory syndrome

,

irritable bowel syndrome

,

dentofacial deformities

,

jaw abnormalities

,

port-wine stain

,

capillary hemangioma

,

conscious sedation

,

regenerative endodontics

,

carpal tunnel syndrome

,

,

multiple organ failure

,

,

,

bronchopulmonary dysplasia

,

necrotizing enterocolitis

,

,

retinopathy of prematurity

,

,

carotid stenosis

,

pathologic constriction

,

,

short bowel syndrome

,

esophageal atresia

,

diaphragmatic hernias congenital

,

calcium metabolism disorders

,

uterine cervical neoplasms

,

personal satisfaction

,

stomach neoplasms

,

,

sudden infant death

,

,

bone resorption

,

skin pigmentation

,

,

,

severe acute malnutrition

,

gastroenteritis

,

community-acquired pneumonia

,

,

female genital neoplasms

,

spinal injuries

,

,

,

,

,

barrett esophagus

,

peptic esophagitis

,

,

,

replacement arthroplasty

,

hypertrophic cicatrix

,

,

angina pectoris

,

,

unstable angina

,

,

,

,

asphyxia neonatorum

,

photosensitivity disorders

,

ankle fractures

,

,

,

,

psychotic disorders

,

drug-eluting stents

,

accidental injuries

,

,

hereditary congenital and neonatal diseases and abnormalities

,

community-acquired infections

,

,

globus sensation

,

,

neuromuscular diseases

,

obesity hypoventilation syndrome

,

hypoventilation

,

polymerase chain reaction

,

enterococcus faecalis

,

,

rheumatoid arthritis

,

obstetric delivery

,

ultrasonography

,

muscular atrophy

,

spinal muscular atrophy

,

spinal puncture

,

occlusive dressings

,

,

occupational diseases

,

,

vaginal diseases

,

complex regional pain syndromes

,

portal hypertension

,

focal nodular hyperplasia

,

idiopathic noncirrhotic portal hypertension

,

,

temporomandibular joint dysfunction syndrome

,

single-tooth dental implants

,

immunohistochemistry

,

,

forearm injuries

,

autism spectrum disorder

,

,

,

cigarette smoking

,

,

denture stomatitis

,

,

patient satisfaction

,

,

pilonidal sinus

,

ischemic stroke

,

,

bilateral hearing loss

,

,

,

,

urinary retention

,

neurogenic urinary bladder

,

premenstrual syndrome

,

metabolic diseases

,

,

caregiver burden

,

,

,

myofascial pain syndromes

,

,

vulvar neoplasms

,

condylomata acuminata

,

intestinal diseases

,

,

essential hypertension

,

pain management

,

kangaroo-mother care method

,

replacement arthroplasty shoulder

,

surgical wound dehiscence

,

cardiac surgical procedures

,

patient acceptance of health care

,

athletic injuries

,

venous thrombosis

,

dental occlusion

,

spinal stenosis

,

,

urinary bladder neoplasms

,

disease progression

,

muscle spasticity

,

,

equinus deformity

,

foot deformities

,

congenital foot deformities

,

,

,

,

,

,

central nervous system sensitization

,

insulin resistance

,

hypersensitivity

,

,

intervertebral disc displacement

,

,

laughter therapy

,

,

radius fractures

,

wrist fractures

,

colorectal neoplasms

,

tooth extraction

,

laparoscopic cholecystectomy

,

anxiety disorders

,

,

,

,

,

,

blood coagulation

,

brain concussion

,

acute kidney injury

,

pulmonary infarction

,

gastrointestinal hemorrhage

,

nutritional support

,

skin transplantation

,

chronic disease

,

hip osteoarthritis

,

femur head necrosis

,

gingival hyperplasia

,

artificial respiration

,

,

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

lymphoid leukemia

,

renal cell carcinoma

,

kidney neoplasms

,

,

prostatic neoplasms

healthy volunteers/patients

,

colorectal neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

sickle cell anemia

,

knee osteoarthritis

,

,

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

laryngeal neoplasms

,

opioid-related disorders

,

,

coronavirus infections

,

,

,

urinary bladder neoplasms

,

brain neoplasms

,

serous cystadenocarcinoma

,

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

cystic fibrosis

,

,

biliary tract neoplasms

,

,

invasive hydatidiform mole

,

non-muscle invasive bladder neoplasms

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

b-cell lymphoma

,

b-cell leukemia

,

diabetes mellitus

,

chronic obstructive pulmonary disease

,

,

,

obstructive lung diseases

,

non-small-cell lung carcinoma

,

,

pulmonary eosinophilia

,

,

,

,

endometrial neoplasms

,

borderline personality disorder

,

personality disorders

,

churg-strauss syndrome

,

eosinophilic granuloma

,

type 2 diabetes mellitus

,

breast neoplasms

,

,

,

,

endomyocardial fibrosis

,

postoperative pain

,

,

major depressive disorder

,

depressive disorder

actinic keratosis

,

,

,

gastrointestinal hemorrhage

,

,

,

radiodermatitis

,

brain neoplasms

,

,

,

,

,

,

,

,

peripheral nervous system diseases

,

diabetic neuropathies

,

vocal cord paralysis

,

,

,

,

limbal stem cell deficiency

,

disease progression

,

,

endometrial hyperplasia

,

,

,

colorectal neoplasms

,

stomach diseases

,

capsule endoscopy

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

insulin resistance

,

postoperative nausea and vomiting

,

,

,

,

female infertility

,

,

pancreatic fistula

,

,

breast neoplasms

,

,

,

lice infestations

,

irritable bowel syndrome

,

healthy volunteers/patients

,

,

stomach neoplasms

,

,

,

,

drug-related side effects and adverse reactions

,

,

,

,

colonic neoplasms

,

,

relapsing-remitting multiple sclerosis

,

,

chronic renal insufficiency

,

,

delayed graft function

,

adenomatous polyps

,

,

,

hypersensitivity

,

,

,

bariatric surgery

,

postoperative pain

,

,

gastroesophageal reflux

,

urinary incontinence

,

stress urinary incontinence

,

,

,

parasitic diseases

,

,

esophageal neoplasms

,

peptic esophagitis

,

,

,

stevens-johnson syndrome

,

,

atrial fibrillation

,

pleural effusion

,

pericardial effusion

,

,

cardiac tamponade

,

,

,

placenta accreta

,

nasal septal perforation

,

skin abnormalities

,

,

hepatocellular carcinoma

,

liver neoplasms

,

multiple sclerosis

,

,

,

,

,

,

pituitary neoplasms

,

substance-related disorders

,

social behavior

,

vesico-ureteral reflux

,

rheumatoid arthritis

,

,

lactose intolerance

,

,

mite infestations

,

,

,

,

cerebrospinal fluid leak

,

,

skull base neoplasms

,

,

,

,

digestive system endoscopy

,

,

ovarian neoplasms

,

serous cystadenocarcinoma

,

fallopian tube neoplasms

,

,

hereditary breast and ovarian cancer syndrome

,

mullerian mixed tumor

,

,

ovarian neoplasms

,

serous cystadenocarcinoma

,

fallopian tube neoplasms

,

,

hereditary breast and ovarian cancer syndrome

,

mullerian mixed tumor

breast neoplasms

,

head and neck neoplasms

,

,

,

glandular and epithelial neoplasms

,

healthy volunteers/patients

,

,

clostridium infections

,

clostridioides difficile

,

,

postoperative pain

,

,

drug resistant epilepsy

,

consciousness disorders

,

general anesthesia

,

hepatic insufficiency

,

renal insufficiency

,

,

,

,

,

,

overactive urinary bladder

,

parkinson disease

,

central nervous system diseases

,

,

nervous system diseases

,

movement disorders

,

neurodegenerative diseases

,

head and neck neoplasms

,

,

,

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

myelodysplastic syndromes

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

,

lymphoid leukemia

,

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

esophageal neoplasms

,

,

,

postoperative pain

,

,

,

postherpetic neuralgia

,

general anesthesia

,

,

,

,

muscle relaxation

,

delayed emergence from anesthesia

Histone-arginine methyltransferase carm1

,

pharmacokinetics

,

,

,

ocular hypertension

,

open-angle glaucoma

,

multiple myeloma

,

plasma cell neoplasms

,

healthy volunteers/patients

,

erectile dysfunction

,

,

gastrointestinal neoplasms

,

neoplasm metastasis

,

,

renal cell carcinoma

,

,

breast neoplasms

,

,

prostatic neoplasms

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

,

,

,

castration-resistant prostatic neoplasms

,

colorectal neoplasms

,

stomach neoplasms

,

,

biliary tract neoplasms

,

,

uterine cervical neoplasms

,

b-cell lymphoma

,

endometrial neoplasms

,

esophageal neoplasms

,

small cell lung carcinoma

,

transitional cell carcinoma

,

chronic hepatitis

,

,

gastrointestinal diseases

,

,

rna virus infections

,

digestive system diseases

,

viral hepatitis human

,

flaviviridae infections

,

general anesthesia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

disorders of excessive somnolence

,

,

papillomavirus infections

,

vaginal neoplasms

,

vulvar neoplasms

,

condylomata acuminata

,

hodgkin disease

,

migraine disorders

,

atherosclerosis

,

uterine neoplasms

,

,

mullerian mixed tumor

,

,

esophageal squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

neuroendocrine tumors

,

intestinal neoplasms

,

head and neck neoplasms

,

prostatic hyperplasia

,

,

muscular atrophy

,

,

,

urologic neoplasms

,

hepatocellular carcinoma

,

urinary bladder neoplasms

,

liver neoplasms

,

microsatellite instability

,

hidradenitis suppurativa

,

non-small-cell lung carcinoma

,

chronic hepatitis c

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

squamous cell carcinoma of head and neck

,

,

,

squamous cell carcinoma

,

,

,

urinary tract infections

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

,

polycystic kidney diseases

,

,

spondylarthritis

,

,

axial spondyloarthritis

,

,

postherpetic neuralgia

,

,

,

,

,

ovarian neoplasms

,

,

acquired immunodeficiency syndrome

,

,

communicable diseases

,

,

,

,

,

,

kidney diseases

,

rheumatoid arthritis

,

ovarian epithelial carcinoma

,

hepatitis a virus

,

immunosuppression therapy

,

,

chronic renal insufficiency

,

chronic disease

,

drug-related side effects and adverse reactions

,

non-hodgkin lymphoma

,

follicular lymphoma

,

pharmacokinetics

,

,

,

ocular hypertension

,

open-angle glaucoma

,

multiple myeloma

,

plasma cell neoplasms

,

healthy volunteers/patients

,

erectile dysfunction

,

,

gastrointestinal neoplasms

,

neoplasm metastasis

,

renal cell carcinoma

,

,

prostatic neoplasms

,

,

breast neoplasms

,

ovarian neoplasms

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

,

,

,

castration-resistant prostatic neoplasms

,

chronic hepatitis

,

colorectal neoplasms

,

stomach neoplasms

,

,

biliary tract neoplasms

,

,

uterine cervical neoplasms

,

small cell lung carcinoma

,

,

transitional cell carcinoma

,

,

gastrointestinal diseases

,

,

rna virus infections

,

digestive system diseases

,

viral hepatitis human

,

flaviviridae infections

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

disorders of excessive somnolence

,

,

papillomavirus infections

,

vaginal neoplasms

,

vulvar neoplasms

,

condylomata acuminata

,

migraine disorders

,

endometrial neoplasms

,

esophageal neoplasms

,

uterine neoplasms

,

,

mullerian mixed tumor

,

esophageal squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

head and neck neoplasms

,

malignant mesothelioma

,

,

prostatic hyperplasia

,

,

muscular atrophy

,

,

,

urologic neoplasms

,

hepatocellular carcinoma

,

urinary bladder neoplasms

,

liver neoplasms

,

microsatellite instability

,

hidradenitis suppurativa

,

non-small-cell lung carcinoma

,

type 2 diabetes mellitus

,

diabetes mellitus

,

chronic hepatitis c

,

,

squamous cell carcinoma of head and neck

,

,

,

,

squamous cell carcinoma

,

,

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

,

polycystic kidney diseases

,

,

postherpetic neuralgia

,

,

,

,

,

,

,

communicable diseases

,

acquired immunodeficiency syndrome

,

,

,

,

,

,

kidney diseases

,

hepatitis a virus

,

,

chronic renal insufficiency

,

chronic disease

,

drug-related side effects and adverse reactions

1

2

>

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