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Oxurion

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Jetrea	Ocriplasmin	2012-10-17		Retinal diseases

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

prostatic neoplasms

,

retinal vein occlusion

,

urinary bladder neoplasms

,

malignant pleural effusion

,

thrombophlebitis

,

adjuvant chemotherapy

,

,

,

cholecystolithiasis

,

vision disorders

,

peritoneal dialysis

,

continuous ambulatory peritoneal dialysis

,

,

,

hematologic neoplasms

,

,

brain infarction

,

vitreous detachment

,

respiratory insufficiency

,

,

head and neck neoplasms

,

healthy volunteers/patients

,

hypertensive intracranial hemorrhage

,

communicable diseases

,

intracranial vasospasm

,

,

disease progression

,

,

upper extremity deep vein thrombosis

,

,

pathologic processes

,

cerebral arterial diseases

,

congenital heart defects

,

protein-losing enteropathies

,

,

traumatic brain injuries

,

neuroendocrine tumors

,

,

retinal diseases

,

diabetic retinopathy

,

,

,

,

mouth neoplasms

,

oropharyngeal neoplasms

,

neoplasms by site

,

,

hereditary hemorrhagic telangiectasia

,

,

arterial occlusive diseases

,

tissue adhesions

,

cerebral hemorrhage

,

myocardial ischemia

,

,

cardiovascular diseases

,

coronary disease

,

blood coagulation disorders

,

hemostatic disorders

,

respiratory distress syndrome

,

breast neoplasms

,

intracranial hemorrhages

,

cerebrovascular disorders

,

wet macular degeneration

,

intracranial thrombosis

,

vascular diseases

,

macular degeneration

,

cerebral intraventricular hemorrhage

,

nervous system diseases

,

,

retinal artery occlusion

,

acute lung injury

,

newborn respiratory distress syndrome

,

wounds and injuries

,

bites and stings

,

abdominal abscess

,

,

unstable angina

,

,

venous thromboembolism

,

severe acute respiratory syndrome

,

intracranial sinus thrombosis

,

ventricular dysfunction

,

retinal hemorrhage

,

,

catheter obstruction

,

central nervous system diseases

,

,

intracranial aneurysm

,

vascular access devices

,

,

,

,

central venous catheters

,

endovascular procedures

,

,

postphlebitic syndrome

,

angina pectoris

,

percutaneous coronary intervention

,

pericardial effusion

,

acute necrotizing pancreatitis

,

replacement arthroplasty knee

,

chronic limb-threatening ischemia

,

,

genetic skin diseases

,

retinal perforations

,

,

,

,

hemorrhagic stroke

,

coronary thrombosis

,

,

hemorrhagic shock

,

atrial fibrillation

,

,

,

ischemic stroke

,

,

,

myocardial infarction

,

pulmonary embolism

,

cerebral infarction

,

,

,

,

,

st elevation myocardial infarction

,

pleural effusion

,

,

,

venous thrombosis

,

,

subarachnoid hemorrhage

,

coronary artery disease

,

acute coronary syndrome

,

,

pleural empyema

,

thromboembolism

,

inferior wall myocardial infarction

,

middle cerebral artery infarction

,

right ventricular dysfunction

,

,

,

,

drug-related side effects and adverse reactions

,

pleural diseases

,

postthrombotic syndrome

,

,

,

,

thrombolytic therapy

,

,

surgical blood loss

,

heart valve diseases

,

pulmonary infarction

,

pulmonary hypertension

,

short bowel syndrome

,

metabolic syndrome

,

,

,

prehypertension

,

respiratory tract infections

,

,

reperfusion injury

,

injection site reaction

,

patient satisfaction

,

atherosclerosis

,

subdural hematoma

,

postoperative hemorrhage

,

intravenous administration

,

chronic kidney failure

,

,

randomized controlled trials as topic

,

,

,

,

,

,

chronic periodontitis

,

acute kidney injury

,

,

coagulation protein disorders

,

,

thrombotic stroke

,

,

,

,

gastrointestinal hemorrhage

,

,

,

periodontal diseases

,

,

non-st elevated myocardial infarction

,

,

portal hypertension

,

cystic fibrosis

,

hemorrhagic disorders

,

premature birth

,

premature rupture fetal membranes

,

,

,

factor xiii deficiency

,

central serous chorioretinopathy

,

polypoidal choroidal vasculopathy

,

,

,

anxiety disorders

,

,

collateral circulation

,

embolism and thrombosis

,

intracranial embolism and thrombosis

,

intracranial embolism

,

chronic renal insufficiency

,

kidney diseases

,

renal insufficiency

,

retinal arterial macroaneurysm

,

transient ischemic attack

,

kidney transplantation

,

liver transplantation

,

,

rotator cuff injuries

,

atherosclerotic plaque

,

,

bacterial pneumonia

,

,

esophageal neoplasms

,

,

aortic valve stenosis

,

aortic valve insufficiency

,

,

behcet syndrome

,

postoperative complications

,

neonatal sepsis

,

,

prostatic hyperplasia

,

,

myotonic dystrophy

,

,

,

diabetes mellitus

,

type 1 diabetes mellitus

,

disseminated intravascular coagulation

,

,

,

,

,

mediastinal emphysema

,

,

obstetric labor complications

,

aortic dissection

,

antiphospholipid syndrome

,

intracranial arteriosclerosis

,

pathologic constriction

,

periodontal attachment loss

,

,

non-muscle invasive bladder neoplasms

,

environmental biomarkers

,

critical illness

,

systemic inflammatory response syndrome

,

,

,

,

,

ulcerative colitis

,

,

,

,

,

diabetes mellitus

,

retinal vein occlusion

,

vascular diseases

healthy volunteers/patients

,

type 1 diabetes mellitus

,

insulin resistance

,

,

,

,

squamous cell carcinoma of head and neck

,

multiple myeloma

,

head and neck neoplasms

,

,

t-cell lymphoma peripheral

,

,

protein c deficiency

,

plasma cell neoplasms

,

neoplasm metastasis

,

rheumatoid arthritis

,

sleep initiation and maintenance disorders

,

intrinsic sleep disorders

,

granulosa cell tumor

,

wounds and injuries

,

traumatic brain injuries

,

craniocerebral trauma

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

subarachnoid hemorrhage

,

colorectal neoplasms

,

chronic renal insufficiency

,

chronic kidney failure

,

,

,

,

von willebrand diseases

,

non-small-cell lung carcinoma

,

diabetes mellitus

,

primary immunodeficiency diseases

,

essential hypertension

,

,

,

,

ulcerative colitis

,

type 2 diabetes mellitus

,

thrombotic thrombocytopenic purpura

,

cardiovascular diseases

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

philadelphia chromosome

,

lymphoid leukemia

,

,

,

viral pneumonia

,

glucose metabolism disorders

,

,

prostatic neoplasms

,

,

,

ischemic stroke

,

large b-cell lymphoma diffuse

,

interdigitating dendritic cell sarcoma

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

hodgkin disease

,

,

large-cell lymphoma anaplastic

,

,

precocious puberty

,

non-hodgkin lymphoma

,

,

alpha 1-antitrypsin deficiency

,

t-cell lymphoma

,

hematologic diseases

,

chronic obstructive pulmonary disease

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

mucopolysaccharidosis ii

,

Globulin, immune

,

,

acquired immunodeficiency syndrome

,

,

hematologic diseases

,

immunoproliferative disorders

,

pathologic processes

,

neuromyelitis optica

,

aids-related complex

,

blood coagulation disorders

,

hemostatic disorders

,

paraproteinemias

,

hemorrhagic disorders

,

b-cell leukemia

,

,

transverse myelitis

,

psoriatic arthritis

,

bites and stings

,

,

ischemic optic neuropathy

,

respiratory distress syndrome

,

,

wounds and injuries

,

acute lung injury

,

,

newborn respiratory distress syndrome

,

diffuse intrinsic pontine glioma

,

infectious pregnancy complications

,

corneal neovascularization

,

thyroid neoplasms

,

parotid neoplasms

,

intraocular lymphoma

,

eosinophilic esophagitis

,

,

pharyngeal neoplasms

,

tonsillar neoplasms

,

hereditary hemorrhagic telangiectasia

,

,

conjunctival neoplasms

,

,

open-angle glaucoma

,

,

central serous chorioretinopathy

,

,

,

,

hemangioblastoma

,

,

healthy volunteers/patients

,

,

,

brain neoplasms

,

large b-cell lymphoma diffuse

,

,

,

head and neck neoplasms

,

kidney neoplasms

,

,

prostatic neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

multiple myeloma

,

endometrial neoplasms

,

,

b-cell lymphoma marginal zone

,

hypersensitivity

,

retinal diseases

,

mantle-cell lymphoma

,

polypoidal choroidal vasculopathy

,

peritoneal neoplasms

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

salivary gland neoplasms

,

plasma cell neoplasms

,

hodgkin disease

,

uterine cervical neoplasms

,

biliary tract neoplasms

,

hematologic neoplasms

,

pancreatic ductal carcinoma

,

lymphoproliferative disorders

,

cutaneous malignant melanoma

,

radiation injuries

,

hemangiosarcoma

,

,

waldenstrom macroglobulinemia

,

,

oligodendroglioma

,

,

chronic kidney failure

,

,

cholangiocarcinoma

,

central nervous system neoplasms

,

,

malignant fibrous histiocytoma

,

,

meningeal neoplasms

,

meningeal carcinomatosis

,

animal mammary neoplasms

,

urologic neoplasms

,

relapsing-remitting multiple sclerosis

,

,

vascular diseases

,

lymphatic diseases

,

burkitt lymphoma

,

,

,

focal segmental glomerulosclerosis

,

neuroendocrine carcinoma

,

kidney diseases

,

neovascular glaucoma

,

,

squamous cell carcinoma of head and neck

,

,

,

renal insufficiency

,

opsoclonus-myoclonus syndrome

,

unknown primary neoplasms

,

,

von hippel-lindau disease

,

basal cell carcinoma

,

basal cell neoplasms

,

,

benign fibrous histiocytoma

,

local neoplasm recurrence

,

left ventricular dysfunction

,

reactive arthritis

,

osteitis deformans

,

human influenza

,

cytomegalovirus infections

,

cardiovascular diseases

,

atherosclerosis

,

type 1 diabetes mellitus

,

male breast neoplasms

,

residual neoplasm

,

retinal degeneration

,

myeloid leukemia acute

,

,

,

neurofibrosarcoma

,

gastrointestinal stromal tumors

,

endocrine gland neoplasms

,

,

interstitial nephritis

,

adrenocortical carcinoma

,

carotid stenosis

,

vitreous detachment

,

,

angioid streaks

,

precursor cell lymphoblastic leukemia-lymphoma

,

large-cell lymphoma immunoblastic

,

gastrointestinal neoplasms

,

pulmonary alveolar proteinosis

,

churg-strauss syndrome

,

bronchiolitis obliterans syndrome

,

biliary liver cirrhosis

,

,

,

digestive system neoplasms

,

,

,

thymus neoplasms

,

precancerous conditions

,

monoclonal gammopathy of undetermined significance

,

neurofibromatosis 2

,

acoustic neuroma

,

retinal telangiectasis

,

degenerative myopia

,

multifocal choroiditis

,

vitelliform macular dystrophy

,

pseudoxanthoma elasticum

,

peripheral nervous system diseases

,

myasthenia gravis

,

clear cell adenocarcinoma

,

,

vaginal neoplasms

,

vulvar neoplasms

,

gallbladder neoplasms

,

tongue neoplasms

,

,

dermatomyositis

,

,

pseudotumor cerebri

,

,

orbital pseudotumor

,

lymphadenopathy

,

,

autoimmune pancreatitis

,

retroperitoneal fibrosis

,

antiphospholipid syndrome

,

uterine neoplasms

,

giant cell arteritis

,

polymyalgia rheumatica

,

,

benign mucous membrane pemphigoid

,

central nervous system diseases

,

,

diabetic nephropathies

,

,

renal hypertension

,

,

orbital diseases

,

,

ocular motility disorders

,

,

pathologic neovascularization

,

germ cell and embryonal neoplasms

,

oropharyngeal neoplasms

,

hairy cell leukemia

,

spinocerebellar degenerations

,

food hypersensitivity

,

chronic obstructive pulmonary disease

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

non-hodgkin lymphoma

,

,

ovarian neoplasms

,

neoplasm metastasis

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma

,

fallopian tube neoplasms

,

,

lymphoid leukemia

,

follicular lymphoma

,

pancreatic neoplasms

,

renal cell carcinoma

,

diabetic retinopathy

,

,

rectal neoplasms

,

colonic neoplasms

,

ovarian epithelial carcinoma

,

diabetes mellitus

,

triple negative breast neoplasms

,

,

thrombocytopenic purpura idiopathic

,

,

kidney transplantation

,

peanut hypersensitivity

,

multiple sclerosis

,

thrombocytopenic purpura

,

,

wet macular degeneration

,

neuroendocrine tumors

,

lupus nephritis

,

vision disorders

,

systemic lupus erythematosus

,

chronic progressive multiple sclerosis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

thrombotic thrombocytopenic purpura

,

,

systemic vasculitis

,

membranous glomerulonephritis

,

retinal detachment

,

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

,

nephrotic syndrome

,

,

diffuse cerebral sclerosis of schilder

,

interstitial lung diseases

,

macular degeneration

,

colorectal neoplasms

,

,

,

rheumatoid arthritis

,

hepatocellular carcinoma

,

liver neoplasms

,

retinal vein occlusion

,

choroidal neovascularization

,

granulomatosis with polyangiitis

,

chronic urticaria

,

microscopic polyangiitis

,

,

,

,

,

bullous pemphigoid

,

iga glomerulonephritis

,

,

,

retinal neovascularization

,

immune system diseases

,

autoimmune diseases

,

nervous system diseases

,

demyelinating diseases

,

,

premature birth

,

sickle cell anemia

,

,

,

atopic dermatitis

,

,

kaposi varicelliform eruption

,

,

diabetic retinopathy

,

diabetes mellitus

,

retinal telangiectasis

,

,

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