Ocular Therapeutix - PharmaKB

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Company ReportsOcular Therapeutix

Ocular Therapeutix(OCUL)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Dextenza	Dexamethasone	2018-11-30	2023-2039	Leukemia , Septic shock , Ulcerative colitis , Ankylosing spondylitis , Macular edema , Vomiting , Nausea , Uveitis , Sarcoidosis , Thrombocytopenic purpura idiopathic , Pulmonary tuberculosis , Mycosis fungoides , Systemic lupus erythematosus , Rheumatic diseases , Bursitis , Keratitis , Allergic rhinitis perennial , Thyroiditis , Iritis , Hypercalcemia , Brain edema , Pemphigus , Addison disease , Collagen diseases , Dermatitis herpetiformis , Wounds and injuries , Gastrointestinal diseases , Bacterial infections , Pseudomonas infections , Bacterial skin diseases , Skin diseases , Escherichia coli infections , Soft tissue infections , Bacterial eye infections , Urinary bladder diseases , Hepatic encephalopathy , Bacterial meningitis , Bacteremia , Klebsiella infections , Otitis externa , Haemophilus infections , Respiratory tract infections , Urinary tract infections , Intraabdominal infections , Infectious skin diseases , Staphylococcal infections , Central nervous system infections , Infectious bone diseases , Neutropenia , Prostatitis , Fever , Sinusitis , Typhoid fever , Diarrhea , Gonorrhea , Osteomyelitis , Campylobacter infections , Bacterial conjunctivitis , Infectious arthritis , Pyelonephritis , Proteus infections , Anthrax , Protozoan infections , Cystitis , Dysentery , Bacteroides infections , Pain , Ventricular tachycardia , Cardiac arrhythmias , Burns , Esophageal diseases , Ventricular fibrillation , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

dry eye syndromes

,

,

,

anterior uveitis

,

,

corneal diseases

,

,

,

,

,

,

,

,

,

allergic conjunctivitis

,

sjogren's syndrome

Dexamethasone sodium phosphate

,

philadelphia chromosome

,

neoplasm metastasis

,

malignant mesothelioma

,

,

lymphoid leukemia

,

breast neoplasms

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

non-hodgkin lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

t-cell leukemia

,

b-cell leukemia

,

renal insufficiency

,

adrenocortical adenoma

,

endometrial stromal sarcoma

,

,

,

gouty arthritis

,

prostatic neoplasms

,

mantle-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

vision disorders

,

myeloid leukemia acute

,

congenital abnormalities

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

basophilic leukemia acute

,

erythroblastic leukemia acute

,

eosinophilic leukemia acute

,

retinal vein occlusion

,

allergic conjunctivitis

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

,

,

herpes zoster ophthalmicus

,

dry eye syndromes

,

meibomian gland dysfunction

,

,

keratoconjunctivitis

,

,

adenoviridae infections

,

,

,

retinal vein occlusion

,

macular degeneration

,

diabetic retinopathy

,

choroidal neovascularization

,

pathologic neovascularization

,

keratoconjunctivitis sicca

attention deficit disorder with hyperactivity

Calcium dobesilate

,

,

,

,

allergic conjunctivitis

,

sjogren's syndrome

,

dry eye syndromes

macular degeneration

,

choroidal neovascularization

,

ocular hypertension

,

,

open-angle glaucoma

,

geographic atrophy

,

,

fuchs' endothelial dystrophy

,

Globulin, immune

healthy volunteers/patients

,

bcr-abl positive chronic myelogenous leukemia

,

acquired immunodeficiency syndrome

,

,

,

,

glandular and epithelial neoplasms

,

,

gata2 deficiency

,

central nervous system neoplasms

,

,

fallopian tube diseases

,

neurologic manifestations

,

,

atopic dermatitis

,

,

,

myeloproliferative disorders

,

nerve sheath neoplasms

,

neoplasms by histologic type

,

adenosquamous carcinoma

,

,

,

behcet syndrome

,

relapsing polychondritis

,

myasthenia gravis

,

mouth neoplasms

,

,

immunosuppression therapy

,

pancreatic neoplasms

,

transitional cell carcinoma

,

urologic neoplasms

,

ovarian neoplasms

,

squamous cell carcinoma

,

,

,

,

b-cell chronic lymphocytic leukemia

,

malignant mesothelioma

,

pancreatic ductal carcinoma

,

biliary tract neoplasms

,

large b-cell lymphoma diffuse

,

,

uterine cervical neoplasms

,

castration-resistant prostatic neoplasms

,

endometrial neoplasms

,

plasma cell neoplasms

,

uveal neoplasms

,

,

hematologic neoplasms

,

neoplasms by site

,

b-cell lymphoma

,

myeloid leukemia acute

,

squamous cell neoplasms

,

follicular lymphoma

,

microsatellite instability

,

t-cell lymphoma

,

graft vs host disease

,

neuroendocrine tumors

,

myelodysplastic syndromes

,

mantle-cell lymphoma

,

t-cell lymphoma peripheral

,

,

,

,

gastrointestinal neoplasms

,

adenocarcinoma of lung

,

cholangiocarcinoma

,

lymphoid leukemia

,

myeloid leukemia

,

interstitial lung diseases

,

urogenital neoplasms

,

merkel cell carcinoma

,

spinocerebellar degenerations

,

laryngeal diseases

,

,

,

psychology rejection

,

smoldering multiple myeloma

,

clear cell adenocarcinoma

,

,

,

medulloblastoma

,

,

,

rhabdomyosarcoma

,

b-cell leukemia

,

b-cell lymphoma marginal zone

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

prostatic diseases

,

penile neoplasms

,

diffuse intrinsic pontine glioma

,

,

autoimmune diseases

,

multiple sclerosis

,

waldenstrom macroglobulinemia

,

extranodal nk-t-cell lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

burkitt lymphoma

,

female genital neoplasms

,

peritoneal neoplasms

,

salivary gland neoplasms

,

endometrioid carcinoma

,

,

,

organ transplantation

,

neuroendocrine carcinoma

,

urinary bladder diseases

,

carcinoid tumor

,

basal cell carcinoma

,

basal cell neoplasms

,

diffuse scleroderma

,

,

heart transplantation

,

,

male breast neoplasms

,

,

tertiary lymphoid structures

,

oropharyngeal neoplasms

,

,

non-muscle invasive bladder neoplasms

,

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

bronchiolitis obliterans syndrome

,

common variable immunodeficiency

,

male genital neoplasms

,

large-cell lymphoma anaplastic

,

,

phenylketonurias

,

bile duct neoplasms

,

serous cystadenocarcinoma

,

papillary thyroid cancer

,

,

genetic therapy

,

uterine neoplasms

,

large cell carcinoma

,

endometrial stromal tumors

,

small cell carcinoma

,

adrenocortical carcinoma

,

thoracic neoplasms

,

,

thymus neoplasms

,

digestive system diseases

,

,

,

,

,

,

invasive hydatidiform mole

,

,

,

,

bronchiolo-alveolar adenocarcinoma

,

drug-related side effects and adverse reactions

,

thyroid neoplasms

,

precancerous conditions

,

bronchopulmonary dysplasia

,

tobacco smoking

,

meningeal carcinomatosis

,

systemic scleroderma

,

patient preference

,

,

oral leukoplakia

,

germ cell and embryonal neoplasms

,

churg-strauss syndrome

,

microscopic polyangiitis

,

,

hypersensitivity

,

oligodendroglioma

,

,

,

ankylosing spondylitis

,

,

alopecia areata

,

inflammatory breast neoplasms

,

,

,

gastrointestinal stromal tumors

,

male urogenital diseases

,

female urogenital diseases

,

female urogenital diseases and pregnancy complications

,

urogenital diseases

,

reactive arthritis

,

alzheimer disease

,

hereditary nonpolyposis colorectal neoplasms

,

,

,

,

colorectal neoplasms

,

neoplasm metastasis

,

squamous cell carcinoma of head and neck

,

prostatic neoplasms

,

breast neoplasms

,

liver neoplasms

,

head and neck neoplasms

,

multiple myeloma

,

hepatocellular carcinoma

,

,

urinary bladder neoplasms

,

stomach neoplasms

,

,

small cell lung carcinoma

,

brain neoplasms

,

hodgkin disease

,

colonic neoplasms

,

non-hodgkin lymphoma

,

,

,

triple negative breast neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

cutaneous malignant melanoma

,

ulcerative colitis

,

fallopian tube neoplasms

,

,

systemic lupus erythematosus

,

ovarian epithelial carcinoma

,

,

sjogren's syndrome

,

esophageal squamous cell carcinoma

,

,

juvenile arthritis

,

,

coronavirus infections

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

immunoglobulin g4-related disease

,

lupus nephritis

,

giant cell arteritis

,

,

granulomatosis with polyangiitis

,

polymyalgia rheumatica

,

respiratory tract diseases

,

vascular diseases

,

,

systemic vasculitis

,

disease progression

,

pathologic complete response

,

,

,

non-small-cell lung carcinoma

,

rheumatoid arthritis

,

renal cell carcinoma

,

,

kidney transplantation

,

kidney neoplasms

,

,

graft rejection

,

psoriatic arthritis

,

delayed graft function

,

chronic kidney failure

,

transplantation

,

,

epstein-barr virus infections

,

,

coronary artery disease

,

spondylarthritis

,

,

biliary liver cirrhosis

,

,

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

type 1 diabetes mellitus

,

islets of langerhans transplantation

healthy volunteers/patients

,

stomach neoplasms

,

castration-resistant prostatic neoplasms

,

,

,

hepatic insufficiency

,

esophageal neoplasms

,

transitional cell carcinoma

,

uterine cervical neoplasms

,

small cell lung carcinoma

,

merkel cell carcinoma

,

colorectal neoplasms

,

hepatocellular carcinoma

,

,

,

liver neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

neoplasm metastasis

,

endometrial neoplasms

,

,

,

pheochromocytoma

,

,

,

non-hodgkin lymphoma

,

multiple myeloma

,

alveolar soft part sarcoma

,

,

adenoid cystic carcinoma

,

carcinoid tumor

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

malignant mesothelioma

,

,

hemangiosarcoma

,

,

pancreatic neoplasms

,

breast neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

myeloid leukemia

,

,

,

renal cell carcinoma

,

,

,

kidney neoplasms

,

non-small-cell lung carcinoma

,

neuroendocrine tumors

,

pancreatic ductal carcinoma

,

ovarian neoplasms

,

neoadjuvant therapy

,

,

gastrointestinal stromal tumors

,

mantle-cell lymphoma

Bos taurus adrenal cortex corticosteroids

,

atrial fibrillation

,

,

coronary artery disease

,

,

chronic renal insufficiency

,

chronic kidney failure

,

kidney transplantation

,

pulmonary fibrosis

,

secondary hyperparathyroidism

Fluoroquinolone

,

type 2 diabetes mellitus

,

long qt syndrome

,

,

alzheimer disease

,

,

,

,

,

,

photosensitivity disorders

,

chronic renal insufficiency

,

kidney diseases

,

migraine disorders

,

pulmonary arterial hypertension

,

,

coronary artery disease

,

cardiovascular abnormalities

,

erectile dysfunction

,

major depressive disorder

,

electrocardiography

,

,

,

,

rheumatoid arthritis

,

,

,

therapeutic equivalency

,

,

psychotic disorders

,

,

thrombocytopenic purpura idiopathic

,

,

renal cell carcinoma

,

polycythemia vera

,

duchenne muscular dystrophy

,

autoimmune diseases

,

orthostatic hypotension

,

acute coronary syndrome

,

lecithin cholesterol acyltransferase deficiency

,

,

lice infestations

,

restless legs syndrome

,

marijuana abuse

,

falciparum malaria

,

allergic rhinitis

,

,

retinal diseases

,

,

,

alcoholic liver cirrhosis

,

alcoholic hepatitis

,

hepatolenticular degeneration

,

,

acinetobacter infections

,

systemic lupus erythematosus

,

,

renal insufficiency

,

,

premature obstetric labor

,

premature birth

,

,

,

respiration disorders

,

,

,

,

,

human experimentation

,

myocardial ischemia

,

phase i metabolic detoxication

,

periapical periodontitis

,

,

phototoxic dermatitis

,

,

,

,

,

short bowel syndrome

,

non-alcoholic fatty liver disease

,

alcoholic fatty liver

,

smoking cessation

,

multiple endocrine neoplasia type 1

,

postpartum hemorrhage

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

respiratory syncytial virus infections

,

bacterial vaginosis

,

retinal vein occlusion

,

,

choroidal neovascularization

,

pathologic neovascularization

,

sickle cell anemia

,

,

,

pharmacokinetics

,

,

escherichia coli infections

,

,

infectious arthritis

,

,

,

,

otorhinolaryngologic diseases

,

parkinson disease

,

methicillin-resistant staphylococcus aureus

,

,

pharmacological phenomena

,

pulmonary sarcoidosis

,

,

refractive errors

,

,

pancreatic ductal carcinoma

,

systemic inflammatory response syndrome

,

,

,

,

amyotrophic lateral sclerosis

,

anastomotic leak

,

cutaneous leishmaniasis

,

mycobacterium avium-intracellulare infection

,

staphylococcal skin infections

,

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

neoplasm metastasis

,

,

anorexia nervosa

,

,

,

graft vs host disease

,

muscle spasticity

,

interstitial lung diseases

,

myeloid leukemia

,

lymphoid leukemia

,

hepatopulmonary syndrome

,

corneal injuries

,

,

rectal neoplasms

,

,

,

castration-resistant prostatic neoplasms

,

periapical diseases

,

colorectal neoplasms

,

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

,

,

community-acquired infections

,

extensively drug-resistant tuberculosis

,

multiple myeloma

,

respiratory tract diseases

,

latent tuberculosis

,

myelodysplastic syndromes

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

mycobacterium infections

,

prosthesis-related infections

,

wounds and injuries

,

large b-cell lymphoma diffuse

,

aids-related opportunistic infections

,

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

plasma cell neoplasms

,

,

,

,

,

congenital abnormalities

,

,

healthcare-associated pneumonia

,

urologic diseases

,

bronchial diseases

,

myeloproliferative disorders

,

sezary syndrome

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

,

clostridium infections

,

meningeal tuberculosis

,

human influenza

,

nontuberculous mycobacterium infections

,

enterobacteriaceae infections

,

neurogenic urinary bladder

,

biphenotypic leukemia acute

,

,

,

,

wound infection

,

abdominal abscess

,

pelvic infection

,

ovarian neoplasms

,

myelomonocytic leukemia chronic

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

hairy cell leukemia

,

testicular neoplasms

,

,

paranasal sinus diseases

,

,

hematopoietic stem cell transplantation

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

intraocular lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

central nervous system neoplasms

,

,

,

phenylketonurias

,

mycobacterium tuberculosis

,

,

,

,

musculoskeletal pain

,

systolic heart failure

,

sick sinus syndrome

,

,

,

gram-positive bacterial infections

,

triple negative breast neoplasms

,

,

primary myelofibrosis

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

gestational trophoblastic disease

,

ovarian epithelial carcinoma

,

neutrophilic leukemia chronic

,

trophoblastic neoplasms

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

ocular hypertension

,

open-angle glaucoma

,

,

,

sphenoid sinusitis

,

,

prolymphocytic leukemia

,

large granular lymphocytic leukemia

,

,

small cell lung carcinoma

,

phacoemulsification

,

acute cholecystitis

,

,

esophageal and gastric varices

,

intestinal neoplasms

,

nervous system neoplasms

,

salivary gland diseases

,

neurologic manifestations

,

,

acquired joint deformities

,

,

hematologic diseases

,

acanthamoeba keratitis

,

agammaglobulinemia

,

hidradenitis suppurativa

,

,

lymph node tuberculosis

,

prostatic diseases

,

healthy volunteers/patients

,

,

urinary tract infections

,

communicable diseases

,

,

,

pulmonary tuberculosis

,

chronic obstructive pulmonary disease

,

bacterial infections

,

multidrug-resistant tuberculosis

,

helicobacter infections

,

community-acquired pneumonia

,

,

,

,

,

,

respiratory tract infections

,

chronic bronchitis

,

,

bacterial conjunctivitis

,

,

,

liver cirrhosis

,

,

,

bacterial pneumonia

,

,

cystic fibrosis

,

endophthalmitis

,

,

febrile neutropenia

,

myeloid leukemia acute

,

,

,

,

diabetes mellitus

,

,

,

prostatic neoplasms

,

breast neoplasms

,

,

cataract extraction

,

,

,

disease susceptibility

,

precursor cell lymphoblastic leukemia-lymphoma

,

disease progression

,

non-hodgkin lymphoma

,

pseudomonas infections

,

,

,

,

,

,

,

intraabdominal infections

,

,

respiratory aspiration

,

,

,

urinary bladder neoplasms

,

,

corneal diseases

,

,

,

cardiovascular diseases

,

,

,

,

maxillary sinusitis

,

critical illness

,

nephrolithiasis

,

,

,

insulin resistance

,

,

drug-related side effects and adverse reactions

,

prostatic hyperplasia

,

microbial drug resistance

,

surgical wound infection

,

retinal detachment

,

obstructive lung diseases

,

overactive urinary bladder

,

,

ventilator-associated pneumonia

,

,

inflammatory bowel diseases

,

dental pulp necrosis

,

postoperative pain

,

,

cardiac arrhythmias

,

cross infection

,

,

pelvic inflammatory disease

,

,

,

antibiotic prophylaxis

,

,

hematologic neoplasms

,

bacillary dysentery

,

,

mycoplasma pneumonia

,

pyogenic liver abscess

,

osteoarticular tuberculosis

,

,

ulcerative colitis

,

otitis media with effusion

,

pancreatic neoplasms

,

macular degeneration

,

pseudomonas aeruginosa

,

,

hypersensitivity

,

aspiration pneumonia

,

chronic periodontitis

,

corneal transplantation

,

bacterial eye infections

,

aggressive periodontitis

,

soft tissue infections

,

meningococcal meningitis

,

pancreatic cyst

,

gastroenteritis

,

postoperative complications

,

chlamydia infections

,

adaptive immunity

,

klebsiella infections

,

,

pneumococcal pneumonia

,

periapical abscess

,

patient preference

,

suppurative otitis media

,

,

,

intravenous substance abuse

,

contraception behavior

,

heart disease risk factors

,

glucose intolerance

,

,

,

intravitreal injections

,

patient compliance

,

metabolic syndrome

,

,

intravesical administration

,

non-muscle invasive bladder neoplasms

,

mycoplasma pneumoniae

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

kidney transplantation

,

polyomavirus infections

,

,

,

,

,

penetrating eye injuries

,

,

ophthalmologic surgical procedures

,

hepatorenal syndrome

,

,

hereditary angioedemas

,

ureteral calculi

,

,

herpesviridae infections

,

bacterial endocarditis

,

,

,

pulmonary infarction

,

haemophilus infections

,

,

urinary diversion

,

,

colonic diverticulitis

,

staphylococcal infections

,

,

ischemic stroke

,

bacterial drug resistance

,

staphylococcus aureus

,

,

,

pathologic dilatation

,

drug monitoring

,

deglutition disorders

,

clostridioides difficile

,

,

aortic dissection

,

,

mycoplasma infections

,

pleuropneumonia

,

,

inappropriate prescribing

,

chemical and drug induced liver injury

,

,

venous thrombosis

,

drug resistance

,

,

,

,

,

,

,

hyperaldosteronism

,

,

sleep initiation and maintenance disorders

,

,

,

,

general anesthesia

,

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

bipolar disorder

,

autistic disorder

,

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

asymptomatic infections

,

,

,

extracorporeal circulation

,

,

,

precancerous conditions

,

,

,

stenotrophomonas maltophilia

,

percutaneous nephrolithotomy

,

,

dissociative disorders

,

,

reactive arthritis

,

chronic kidney failure

,

musculoskeletal diseases

,

catheter-related infections

,

portal hypertension

,

myocardial revascularization

,

emergency treatment

,

,

,

multiple drug resistance

,

physical exertion

,

laboratory infection

,

,

uterine hemorrhage

,

spontaneous abortion

,

blood transfusion

,

lymphatic diseases

,

traumatic brain injuries

,

pleural empyema

,

root resorption

,

persistent infection

,

torsades de pointes

,

emerging communicable diseases

,

,

emergence delirium

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