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Company ReportsKiniksa Pharmaceuticals

Kiniksa Pharmaceuticals(KNSA)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Arcalyst	Rilonacept	2008-02-27		Inborn genetic diseases , Inflammation , Cryopyrin-associated periodic syndromes

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

rheumatoid arthritis

,

,

respiratory insufficiency

,

severe acute respiratory syndrome-related coronavirus

,

,

,

respiratory distress syndrome

,

viral pneumonia

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

,

,

breast neoplasms

,

triple negative breast neoplasms

,

,

cytomegalovirus retinitis

,

,

healthy volunteers/patients

,

b-cell chronic lymphocytic leukemia

,

,

colonic neoplasms

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

knee osteoarthritis

,

,

,

,

rectal neoplasms

,

lymphoid leukemia

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

,

glycogen storage disease

,

,

deficiency diseases

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

,

falciparum malaria

,

hereditary nephritis

,

,

,

,

viral hemorrhagic fevers

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

langerhans-cell histiocytosis

,

hypersensitivity

,

peanut hypersensitivity

,

allergic rhinitis

,

,

esophageal neoplasms

,

stomach neoplasms

,

,

myeloid leukemia acute

,

myeloid leukemia

,

colorectal neoplasms

,

prostatic neoplasms

,

venous thromboembolism

,

thromboembolism

,

primary myelofibrosis

,

hypercholesterolemia

,

gaucher disease

,

head and neck neoplasms

,

rheumatoid arthritis

,

,

hematologic neoplasms

,

,

,

thyroid neoplasms

,

thyroid diseases

,

multiple myeloma

,

plasma cell neoplasms

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

,

tay-sachs disease

,

sandhoff disease

,

,

,

,

haemophilus influenzae type b

,

,

,

neurotoxicity syndromes

,

brugada syndrome

,

chronic kidney failure

,

renal insufficiency

,

type 2 diabetes mellitus

,

diabetes mellitus

,

type 1 diabetes mellitus

,

glycogen storage disease type ii

,

,

atopic dermatitis

,

,

,

,

human influenza

,

,

,

,

,

atrial fibrillation

,

,

,

meningococcal infections

,

,

sedentary behavior

,

,

wounds and injuries

,

heart transplantation

,

reperfusion injury

,

,

,

clostridium infections

,

,

chronic renal insufficiency

,

kidney diseases

,

cardiovascular diseases

,

,

,

prostatic neoplasms

,

,

,

malignant mesothelioma

,

,

multiple myeloma

,

plasma cell neoplasms

,

ovarian neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

peritoneal neoplasms

,

,

parkinson disease

,

,

,

diffuse intrinsic pontine glioma

,

,

acquired immunodeficiency syndrome

,

plasma cell leukemia

,

basal cell carcinoma

,

t-cell lymphoma cutaneous

,

basal cell neoplasms

,

stem cell transplantation

,

hereditary breast and ovarian cancer syndrome

,

waldenstrom macroglobulinemia

,

paraproteinemias

,

,

precancerous conditions

,

smoldering multiple myeloma

,

,

carcinoid tumor

,

healthy volunteers/patients

,

respiratory syncytial virus infections

,

,

,

phenylketonurias

,

myasthenia gravis

,

muscle weakness

,

,

acinar cell carcinoma

,

conjunctival neoplasms

,

,

clear cell sarcoma

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

testicular neoplasms

,

breast diseases

,

medullary carcinoma

,

mammary paget's disease

,

thrombocytopenia

,

paroxysmal hemoglobinuria

,

,

,

parkinsonian disorders

,

pharmacokinetics

,

lymphatic metastasis

,

,

,

ovarian neoplasms

,

colorectal neoplasms

,

,

ovarian epithelial carcinoma

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

fallopian tube neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

myeloproliferative disorders

,

stomach neoplasms

,

b-cell lymphoma

,

brain neoplasms

,

liver neoplasms

,

myelodysplastic-myeloproliferative diseases

,

,

,

,

respiratory distress syndrome

,

male breast neoplasms

,

germ cell and embryonal neoplasms

,

colonic neoplasms

,

malignant mesothelioma

,

,

hematologic neoplasms

,

hodgkin disease

,

squamous cell carcinoma

,

oligodendroglioma

,

medulloblastoma

,

,

peritoneal neoplasms

,

follicular lymphoma

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

acute lung injury

,

newborn respiratory distress syndrome

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

myeloid leukemia chronic-phase

,

small cell lung carcinoma

,

rectal neoplasms

,

mantle-cell lymphoma

,

,

,

castration-resistant prostatic neoplasms

,

alzheimer disease

,

endometrial neoplasms

,

drug-related side effects and adverse reactions

,

peripheral arterial disease

,

peripheral vascular diseases

,

uterine cervical neoplasms

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

hepatocellular carcinoma

,

respiratory aspiration

,

alveolar soft part sarcoma

,

inflammatory breast neoplasms

,

,

graft vs host disease

,

rheumatoid arthritis

,

intestinal neoplasms

,

endometrioid carcinoma

,

merkel cell carcinoma

,

squamous cell neoplasms

,

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

neuroendocrine tumors

,

severe acute respiratory syndrome

,

carcinoma in situ

,

ductal carcinoma breast

,

,

cystic fibrosis

,

nontuberculous mycobacterium infections

,

mycobacterium infections

,

pancreatic ductal carcinoma

,

myelomonocytic leukemia acute

,

transitional cell carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

myeloid leukemia accelerated phase

,

residual neoplasm

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

gastrointestinal neoplasms

,

immunologic deficiency syndromes

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

immunoglobulin light-chain amyloidosis

,

,

lymphoproliferative disorders

,

aplastic anemia

,

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

biliary tract neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

,

adenocarcinoma in situ

,

,

cognitive dysfunction

,

,

severe acute respiratory syndrome-related coronavirus

,

,

unilateral breast neoplasms

,

hypersensitivity

,

kidney diseases

,

kidney transplantation

,

critical illness

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

,

,

invasive hydatidiform mole

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

bile duct neoplasms

,

laryngeal neoplasms

,

burkitt lymphoma

,

ulcerative colitis

,

,

,

urologic neoplasms

,

,

,

,

,

soft tissue neoplasms

,

breast neoplasms

,

prostatic neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

,

,

non-hodgkin lymphoma

,

,

,

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

pancreatic neoplasms

,

pulmonary alveolar proteinosis

,

renal cell carcinoma

,

,

,

uveal neoplasms

,

autoimmune diseases

,

communicable diseases

,

,

triple negative breast neoplasms

,

rhabdomyosarcoma

,

,

,

,

cutaneous malignant melanoma

,

refractory anemia

,

head and neck neoplasms

,

,

ganglioneuroblastoma

,

,

large b-cell lymphoma diffuse

,

refractory anemia with excess of blasts

,

,

urinary bladder neoplasms

,

radiation effects

,

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

hematologic diseases

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

coronavirus infections

,

,

,

invasive fungal infections

,

,

,

tongue neoplasms

,

,

,

,

,

myeloid leukemia

,

myeloid leukemia acute

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

chronic hepatitis b

,

,

,

chronic hepatitis

,

,

,

,

wounds and injuries

,

,

respiratory insufficiency

,

bone marrow failure disorders

,

,

,

liver cirrhosis

,

healthy volunteers/patients

,

,

chronic renal insufficiency

,

knee osteoarthritis

,

,

,

hepatic insufficiency

,

,

telomeric repeat binding protein 2

,

,

plexiform neurofibroma

,

therapeutic equivalency

,

pharmacokinetics

,

biological availability

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

uveal neoplasms

,

,

,

rhabdomyosarcoma

,

,

,

head and neck neoplasms

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

squamous cell neoplasms

,

pancreatic neoplasms

,

endometrial neoplasms

,

multiple myeloma

,

urinary bladder neoplasms

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

chronic obstructive pulmonary disease

,

esophageal neoplasms

,

serous cystadenocarcinoma

,

colonic neoplasms

,

hematologic neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

obstructive lung diseases

,

follicular lymphoma

,

uterine neoplasms

,

,

mullerian mixed tumor

,

,

waldenstrom macroglobulinemia

,

,

uterine cervical neoplasms

,

cardiovascular diseases

,

peritoneal neoplasms

,

,

hereditary breast and ovarian cancer syndrome

,

pancreatic ductal carcinoma

,

small cell carcinoma

,

b-cell lymphoma marginal zone

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

respiratory aspiration

,

,

urethral neoplasms

,

ureteral neoplasms

,

pelvic neoplasms

,

castration-resistant prostatic neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

peripheral nervous system diseases

,

malignant mesothelioma

,

,

adrenocortical carcinoma

,

adenocarcinoma of lung

,

salivary gland neoplasms

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

,

pleural effusion

,

malignant pleural effusion

,

thyroid neoplasms

,

,

breast neoplasms

,

,

ovarian neoplasms

,

colorectal neoplasms

,

small cell lung carcinoma

,

large b-cell lymphoma diffuse

,

,

liver neoplasms

,

,

b-cell lymphoma

,

squamous cell carcinoma

,

renal cell carcinoma

,

hepatocellular carcinoma

,

ovarian epithelial carcinoma

,

,

,

stomach neoplasms

,

triple negative breast neoplasms

,

fallopian tube neoplasms

,

biliary tract neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

squamous cell carcinoma of head and neck

,

brain neoplasms

,

transitional cell carcinoma

,

urologic neoplasms

,

,

communicable diseases

,

hypersensitivity

,

endometrioid carcinoma

,

mucinous cystadenocarcinoma

,

clear cell adenocarcinoma

,

acinar cell carcinoma

,

neoplasms by site

,

gastrointestinal stromal tumors

,

male breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

mantle-cell lymphoma

,

kidney diseases

,

,

migraine disorders

,

,

,

,

,

,

,

family relations

,

neurodermatitis

,

ulcerative colitis

,

,

,

,

,

chronic urticaria

,

,

,

systemic scleroderma

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

interstitial lung diseases

,

diffuse scleroderma

,

psoriatic arthritis

,

spondylarthritis

,

,

sleep wake disorders

,

hyperparathyroidism

,

cardiac arrhythmias

,

drug hypersensitivity syndrome

,

spondylarthropathies

,

cutaneous lupus erythematosus

,

,

acute chest syndrome

,

energy metabolism

,

immune tolerance

,

aplastic anemia

,

,

bone marrow failure disorders

,

,

innate immunity

,

vasoconstriction

,

drug interactions

,

proliferative vitreoretinopathy

,

,

fallopian tube neoplasms

,

gastric outlet obstruction

,

intestinal diseases

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

medication adherence

,

,

pathologic constriction

,

,

adrenocortical carcinoma

,

transient tachypnea of the newborn

,

,

,

wet macular degeneration

,

,

ovarian neoplasms

,

myelodysplastic syndromes

,

,

t-cell lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

magnetic resonance imaging

,

nasopharyngeal carcinoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

type 1 diabetes mellitus

,

gestational diabetes

,

head and neck neoplasms

,

,

,

,

erythema nodosum

,

vulvar lichen sclerosus

,

hematologic neoplasms

,

,

,

t-cell lymphoma peripheral

,

,

labyrinth diseases

,

,

ventilator-associated pneumonia

,

congenital heart defects

,

,

port-wine stain

,

capillary hemangioma

,

,

,

,

lung transplantation

,

,

renal cell carcinoma

,

pancreatic neoplasms

,

rhabdomyosarcoma

,

malignant mesothelioma

,

squamous cell neoplasms

,

peritoneal neoplasms

,

ovarian epithelial carcinoma

,

cryoglobulinemia

,

parkinson disease

,

congenital abnormalities

,

,

pituitary acth hypersecretion

,

cushing syndrome

,

esophageal stenosis

,

,

,

,

immediate hypersensitivity

,

out-of-hospital cardiac arrest

,

hematopoietic stem cell transplantation

,

hyperaldosteronism

,

tendon injuries

,

ischemic optic neuropathy

,

adrenal cortex neoplasms

,

mesenchymal stem cell transplantation

,

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

circulating neoplastic cells

,

muscular diseases

,

,

spinal cord injuries

,

philadelphia chromosome

,

kidney neoplasms

,

,

residual neoplasm

,

biphenotypic leukemia acute

,

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

myelomonocytic leukemia juvenile

,

,

embryonal rhabdomyosarcoma

,

pleural effusion

,

,

autoimmune diseases of the nervous system

,

,

high-risk pregnancy

,

hermanski-pudlak syndrome

,

,

drug evaluation

,

,

demyelinating diseases

,

mantle-cell lymphoma

,

schnitzler syndrome

,

hodgkin disease

,

chronic hepatitis c

,

esophageal squamous cell carcinoma

,

malignant pleural effusion

,

pleural diseases

,

arteriovenous malformations

,

central nervous system neoplasms

,

nervous system neoplasms

,

pulmonary arterial hypertension

,

hairy cell leukemia

,

,

langerhans-cell histiocytosis

,

precancerous conditions

,

actinic keratosis

,

,

acth-secreting pituitary adenoma

,

laryngostenosis

,

pelvic girdle pain

,

,

postoperative complications

,

,

leukocytoclastic vasculitis cutaneous

,

aphthous stomatitis

,

,

familial mediterranean fever

,

cognition disorders

,

castleman disease

,

encephalomalacia

,

severe acute respiratory syndrome-related coronavirus

,

low cardiac output

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

egg hypersensitivity

,

,

pulmonary emphysema

,

immunoglobulin g4-related disease

,

post-cardiac arrest syndrome

,

smoldering multiple myeloma

,

urologic neoplasms

,

transitional cell carcinoma

,

mast cell activation syndrome

,

geographic atrophy

,

second primary neoplasms

,

,

,

diffuse intrinsic pontine glioma

,

radiation pneumonitis

,

,

,

,

,

retinitis pigmentosa

,

,

toxic optic neuropathy

,

meningoencephalitis

,

central nervous system tuberculosis

,

esophageal neoplasms

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

,

,

bronchiolitis obliterans syndrome

,

,

lymphoid leukemia

,

multiple myeloma

,

alcoholic hepatitis

,

plasma cell neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

thrombocytopenia

,

neoplasm metastasis

,

,

viral pneumonia

,

colorectal neoplasms

,

giant cell arteritis

,

polymyalgia rheumatica

,

autoimmune diseases

,

pulmonary fibrosis

,

non-hodgkin lymphoma

,

non-small-cell lung carcinoma

,

,

paranasal sinus diseases

,

systemic vasculitis

,

,

nasopharyngeal neoplasms

,

brain neoplasms

,

deglutition disorders

,

,

,

bronchopulmonary dysplasia

,

,

,

,

pulmonary sarcoidosis

,

idiopathic pulmonary fibrosis

,

eosinophilic esophagitis

,

,

thrombotic thrombocytopenic purpura

,

myasthenia gravis

,

,

neuromyelitis optica

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

chronic disease

,

fetal growth retardation

,

bronchiolitis obliterans

,

status asthmaticus

,

,

,

,

,

,

sensorineural hearing loss

,

airway obstruction

,

,

lichen sclerosus et atrophicus

,

dermatomyositis

,

autoimmune hepatitis

,

severe acute respiratory syndrome

,

pathologic neovascularization

,

tendon entrapment

,

retinal diseases

,

urinary tract infections

,

facial paralysis

,

,

,

primary myelofibrosis

,

,

systemic scleroderma

,

diffuse scleroderma

,

focal segmental glomerulosclerosis

,

castration-resistant prostatic neoplasms

,

behcet syndrome

,

metabolic diseases

,

,

follicular lymphoma

,

allergic fungal sinusitis

,

gastroesophageal reflux

,

,

choroidal neovascularization

,

diabetic retinopathy

,

,

,

obstetric labor complications

,

laryngeal edema

,

shoulder injuries

,

meningeal tuberculosis

,

chemical and drug induced liver injury

,

inborn genetic diseases

,

acquired immunodeficiency syndrome

,

sudden hearing loss

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

thyroid diseases

,

,

,

,

,

,

,

delayed graft function

,

sickle cell anemia

,

systemic mastocytosis

,

chondrocalcinosis

,

,

,

,

,

nervous system diseases

,

,

adrenocortical hyperfunction

,

postoperative nausea and vomiting

,

,

takayasu arteritis

,

aortic arch syndromes

,

,

,

meniere disease

,

bacterial pneumonia

,

cardiovascular diseases

,

,

endocrine system diseases

,

,

acanthamoeba keratitis

,

ornithine carbamoyltransferase deficiency disease

,

,

chronic progressive multiple sclerosis

,

alcoholic liver diseases

,

glucose intolerance

,

biliary atresia

,

,

,

sprains and strains

,

endophthalmitis

,

,

human influenza

,

chronic hepatitis

,

genetic skin diseases

,

intravitreal injections

,

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

intracranial hemorrhages

,

necrotizing enterocolitis

,

,

,

coronaviridae infections

,

nidovirales infections

,

rna virus infections

,

peptic esophagitis

,

adenocarcinoma of lung

,

hand-foot syndrome

,

,

,

immunologic deficiency syndromes

,

cochlear implants

,

,

,

ataxia telangiectasia

,

congenital adrenal hyperplasia

,

adrenogenital syndrome

,

,

infantile spasms

,

idiopathic interstitial pneumonias

,

,

inguinal hernia

,

,

,

neurocysticercosis

,

,

,

war-related injuries

,

graft vs host reaction

,

benign mucous membrane pemphigoid

,

spontaneous abortion

,

habitual abortion

,

,

eosinophilic granuloma

,

,

,

,

,

cardiopulmonary bypass

,

liver cirrhosis

,

,

ethmoid sinusitis

,

sphenoid sinusitis

,

patient satisfaction

,

vocal cord paralysis

,

nontuberculous mycobacterium infections

,

,

subdural hematoma intracranial

,

polyneuropathies

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

pulmonary tuberculosis

,

,

,

,

oral submucous fibrosis

,

pregnancy outcome

,

limb-girdle muscular dystrophies

,

,

meconium aspiration syndrome

,

traumatic brain injuries

,

multiple trauma

,

muscle spasticity

,

tropical spastic paraparesis

,

,

spastic paraparesis

,

,

hypoalbuminemia

,

,

,

nutritional and metabolic diseases

,

stevens-johnson syndrome

,

placenta previa

,

cluster headache

,

central nervous system infections

,

,

pyogenic granuloma

,

ulnar neuropathies

,

vulvovaginal candidiasis

,

,

,

clostridium botulinum

,

,

glycogen storage disease type i

,

glycogen storage disease

,

erythema multiforme

,

ventricular dysfunction

,

retinal neovascularization

,

biliary liver cirrhosis

,

,

,

venous thrombosis

,

,

chronic obstructive pulmonary disease

,

,

,

kidney transplantation

,

obstructive lung diseases

,

,

knee osteoarthritis

,

,

,

atopic dermatitis

,

graft vs host disease

,

,

,

,

,

,

,

systemic lupus erythematosus

,

,

allergic rhinitis

,

ulcerative colitis

,

,

,

,

premature birth

,

,

,

,

carpal tunnel syndrome

,

rheumatoid arthritis

,

,

oral lichen planus

,

kidney diseases

,

,

,

respiratory distress syndrome

,

,

,

,

,

disease progression

,

shoulder impingement syndrome

,

,

trigger finger disorder

,

prostatic neoplasms

,

rotator cuff injuries

,

lupus nephritis

,

,

,

graft rejection

,

healthy volunteers/patients

,

renal insufficiency

,

liver transplantation

,

,

,

plantar fasciitis

,

newborn respiratory distress syndrome

,

,

,

hypersensitivity

,

,

respiratory aspiration

,

postoperative pain

,

,

,

bullous pemphigoid

,

,

,

,

multiple sclerosis

,

thrombocytopenic purpura idiopathic

,

,

diabetes mellitus

,

,

,

thrombocytopenic purpura

,

communicable diseases

,

inflammatory bowel diseases

,

,

,

chronic kidney failure

,

dry eye syndromes

,

,

duchenne muscular dystrophy

,

muscular dystrophies

,

iga glomerulonephritis

,

,

,

keratoconjunctivitis sicca

,

,

premature obstetric labor

,

,

breast neoplasms

,

respiratory sounds

,

pulmonary eosinophilia

,

acute lung injury

,

,

adrenal insufficiency

,

glomerulonephritis

,

,

coronavirus infections

,

macular degeneration

,

alopecia areata

,

,

,

granulomatosis with polyangiitis

,

nephrotic syndrome

,

,

membranous glomerulonephritis

,

,

,

hip osteoarthritis

,

,

critical illness

,

cytokine release syndrome

,

immunosuppression therapy

,

heart transplantation

,

,

muscle weakness

,

intervertebral disc displacement

,

respiratory insufficiency

,

,

relapsing-remitting multiple sclerosis

,

,

interstitial lung diseases

,

type 2 diabetes mellitus

,

drug-related side effects and adverse reactions

,

,

respiratory tract diseases

,

wounds and injuries

,

keratoconjunctivitis

,

,

lipoid nephrosis

,

allergic rhinitis perennial

,

chronic renal insufficiency

,

churg-strauss syndrome

,

olfaction disorders

,

intervertebral disc degeneration

,

,

,

immune system diseases

,

microscopic polyangiitis

,

,

sleep apnea syndromes

,

,

allergic rhinitis seasonal

,

,

cytomegalovirus infections

,

cystic fibrosis

,

allergic conjunctivitis

,

,

,

anterior uveitis

,

neurodermatitis

,

,

myeloid leukemia

,

juvenile arthritis

,

myeloid leukemia acute

,

,

atrial fibrillation

,

obstructive sleep apnea

,

respiratory hypersensitivity

,

transplantation

,

respiratory signs and symptoms

,

,

de quervain disease

,

,

hypertrophic cicatrix

,

intra-articular injections

,

respiratory tract infections

,

,

pneumocystis pneumonia

,

spinal stenosis

,

,

,

intraocular pressure

,

,

,

intermediate uveitis

,

posterior uveitis

,

,

squamous cell carcinoma

,

cardiac surgical procedures

,

memory disorders

,

graves ophthalmopathy

,

,

musculoskeletal diseases

,

,

retinal vein occlusion

,

,

cough-variant asthma

,

,

,

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

systemic inflammatory response syndrome

,

migraine disorders

,

subdural hematoma

,

,

subdural hematoma chronic

,

,

vestibular neuronitis

,

,

hypereosinophilic syndrome

,

atherosclerosis

,

,

fuchs' endothelial dystrophy

,

retroperitoneal fibrosis

,

meibomian gland dysfunction

,

rheumatic diseases

,

collagen diseases

,

,

ocular hypertension

,

open-angle glaucoma

,

rotator cuff tear arthropathy

,

pathologic dilatation

,

,

bacterial infections

,

connective tissue diseases

,

pregnancy complications

,

radiodermatitis

,

,

rheumatic fever

,

,

corneal transplantation

,

penetrating keratoplasty

,

vitreoretinal surgery

,

refractive surgical procedures

,

,

,

,

hemophagocytic lymphohistiocytosis

,

,

,

squamous cell carcinoma of head and neck

,

immune reconstitution inflammatory syndrome

,

,

,

,

replacement arthroplasty knee

,

end stage liver disease

,

polyarteritis nodosa

,

allergic bronchopulmonary aspergillosis

,

pulmonary aspergillosis

,

hypoparathyroidism

,

,

respiration disorders

,

,

,

insulin resistance

,

,

,

elbow tendinopathy

,

esophageal diseases

,

pituitary diseases

,

,

,

,

nasal obstruction

,

esophageal achalasia

,

,

,

femoracetabular impingement

,

,

high-energy shock waves

,

dental pulp necrosis

,

,

hypercholesterolemia

,

hepatocellular carcinoma

,

liver neoplasms

,

ultrasonography

,

bronchial diseases

,

,

,

,

renal replacement therapy

,

epstein-barr virus infections

,

cat-scratch disease

,

bartonella infections

,

inborn errors metabolism

,

brachial plexus block

,

ambulatory surgical procedures

,

infectious keratoconjunctivitis

,

,

,

,

,

,

vascular diseases

,

post-traumatic stress disorders

,

traumatic stress disorders

,

intravenous infusions

,

glycemic control

,

airway remodeling

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

invasive fungal infections

,

pancreas transplantation

,

,

drug resistant epilepsy

,

coronary artery disease

,

myocardial ischemia

,

,

artificial respiration

,

acute kidney injury

,

extrinsic allergic alveolitis

,

,

herpetic keratitis

,

vestibular diseases

,

operative surgical procedures

,

fertilization in vitro

,

,

bacterial eye infections

,

multiple organ failure

,

tibial meniscus injuries

,

hematologic diseases

,

leukocyte disorders

,

,

dental pulp diseases

,

localized scleroderma

,

keratoacanthoma

,

granuloma annulare

,

,

,

femoral neck fractures

,

,

hashimoto disease

,

neoplasms by histologic type

,

dupuytren contracture

,

,

connective and soft tissue neoplasms

,

connective tissue neoplasms

,

,

fibrous tissue neoplasms

,

tooth abnormalities

,

,

,

,

,

ischemic stroke

,

arteriosclerosis

,

anterior cruciate ligament reconstruction

,

transcatheter aortic valve replacement

,

bundle-branch block

,

,

,

granulomatous mastitis

,

hyaline membrane disease

,

,

,

,

physical therapy modalities

,

,

uveomeningoencephalitic syndrome

,

metabolic bone diseases

,

,

,

premature rupture fetal membranes

,

,

,

vision disorders

,

perioperative period

,

,

myocardial infarction

,

,

,

vitamin d deficiency

,

,

exercise therapy

,

piriformis muscle syndrome

,

extracorporeal shockwave therapy

,

post-acute covid-19 syndrome

,

pain management

,

epiretinal membrane

,

,

,

,

,

,

,

bronchial hyperreactivity

,

maxillary sinusitis

,

prostatic hyperplasia

,

lower urinary tract symptoms

,

noninvasive ventilation

,

,

major depressive disorder

,

depressive disorder

,

,

alzheimer disease

,

,

venous insufficiency

,

pain measurement

,

epidural analgesia

,

,

clostridium botulinum type a

,

,

polycystic ovary syndrome

,

facial nerve diseases

,

,

pelvic organ prolapse

,

uterine prolapse

,

,

,

,

posterior leukoencephalopathy syndrome

,

descemet stripping endothelial keratoplasty

,

pure autonomic failure

,

cerebral intraventricular hemorrhage

,

infant mortality

,

atrioventricular block

,

ankylosing spondylitis

,

,

,

secondary hyperparathyroidism

,

addison disease

,

migraine without aura

,

post-traumatic headache

,

,

sjogren's syndrome

,

tobacco use disorder

,

tobacco smoking

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

metabolic syndrome

,

hemoglobinopathies

,

,

minimally invasive surgical procedures

,

,

intratracheal intubation

,

failed back surgery syndrome

,

,

choroid diseases

,

,

hypoventilation

,

acupuncture therapy

,

,

spinal cord diseases

,

retinal perforations

,

scleral buckling

,

orthostatic hypotension

,

,

heart valve diseases

,

electroretinography

,

,

pleural tuberculosis

,

peripheral nervous system diseases

,

nerve compression syndromes

,

charcot-marie-tooth disease

,

hereditary sensory and motor neuropathy

,

intralesional injections

,

,

sclerosing cholangitis

,

obstructive jaundice

,

autoimmune pancreatitis

,

drug-eluting stents

,

postoperative care

,

hyperlactatemia

,

,

,

legg-calve-perthes disease

,

,

solid-state lasers

,

,

,

oxidative stress

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

papulosquamous skin diseases

,

hyperpigmentation

,

,

subarachnoid hemorrhage

,

inappropriate adh syndrome

,

,

,

psychotic disorders

,

mental disorders

,

artificial intelligence

,

,

nurse-patient relations

,

,

,

shared decision making

,

enterobacteriaceae infections

,

,

noncommunicable diseases

,

,

,

tibial neuropathy

,

vitreous detachment

,

,

,

phobic disorders

,

gastrointestinal diseases

,

digestive system diseases

,

,

nutrition disorders

,

malabsorption syndromes

,

,

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

status epilepticus

,

injection site reaction

,

eczematous skin diseases

,

,

compression fractures

,

myocardial contraction

,

intermittent claudication

,

colonic neoplasms

,

rectal neoplasms

,

adjuvant chemotherapy

,

,

self-assessment

,

,

patient compliance

,

,

root canal obturation

,

,

whiplash injuries

,

photosensitivity disorders

,

,

angle class i malocclusion

,

,

vasomotor rhinitis

,

healthcare-associated pneumonia

,

nociceptive pain

,

lymph node tuberculosis

,

blood coagulation disorders

,

blood platelet disorders

,

hemostatic disorders

,

coagulation protein disorders

,

nerve degeneration

,

psychophysiologic disorders

,

,

,

,

,

pneumocystis infections

,

aortic dissection

,

thoracic surgical procedures

,

,

,

,

acute liver failure

,

,

organ dysfunction scores

,

,

atrophic vaginitis

,

,

polymerase chain reaction

,

immunocompromised host

,

,

newborn infant diseases

,

cutaneous malignant melanoma

,

conduction anesthesia

,

infectious arthritis

,

,

,

,

,

,

,

lewy body disease

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

cognitive dysfunction

,

,

,

gastrointestinal microbiome

,

,

spinal diseases

,

dust mite allergy

,

pheochromocytoma

,

adrenal rest tumor

,

adrenal gland neoplasms

,

adrenal gland diseases

,

osteoporotic fractures

,

,

inferior wall myocardial infarction

,

,

radius fractures

,

wrist fractures

,

,

musculoskeletal pain

,

,

pregnancy-induced hypertension

,

abruptio placentae

,

neonatal sepsis

,

neonatal jaundice

,

,

asphyxia neonatorum

,

radiofrequency ablation

,

,

,

parkinson disease

,

,

,

diffuse intrinsic pontine glioma

,

,

acquired immunodeficiency syndrome

,

plasma cell leukemia

,

basal cell carcinoma

,

t-cell lymphoma cutaneous

,

basal cell neoplasms

,

stem cell transplantation

,

hereditary breast and ovarian cancer syndrome

,

waldenstrom macroglobulinemia

,

paraproteinemias

,

,

precancerous conditions

,

smoldering multiple myeloma

,

,

carcinoid tumor

,

healthy volunteers/patients

,

respiratory syncytial virus infections

,

,

,

phenylketonurias

,

myasthenia gravis

,

muscle weakness

,

,

acinar cell carcinoma

,

conjunctival neoplasms

,

,

clear cell sarcoma

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

testicular neoplasms

,

breast diseases

,

medullary carcinoma

,

mammary paget's disease

,

thrombocytopenia

,

paroxysmal hemoglobinuria

,

,

,

parkinsonian disorders

,

pharmacokinetics

,

lymphatic metastasis

,

,

ovarian neoplasms

,

,

colorectal neoplasms

,

,

ovarian epithelial carcinoma

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

myeloproliferative disorders

,

fallopian tube neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

stomach neoplasms

,

b-cell lymphoma

,

brain neoplasms

,

hodgkin disease

,

liver neoplasms

,

myelodysplastic-myeloproliferative diseases

,

,

,

,

male breast neoplasms

,

germ cell and embryonal neoplasms

,

colonic neoplasms

,

malignant mesothelioma

,

,

hematologic neoplasms

,

follicular lymphoma

,

squamous cell carcinoma

,

oligodendroglioma

,

respiratory distress syndrome

,

medulloblastoma

,

,

peritoneal neoplasms

,

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

hepatocellular carcinoma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

myeloid leukemia chronic-phase

,

small cell lung carcinoma

,

rectal neoplasms

,

mantle-cell lymphoma

,

,

castration-resistant prostatic neoplasms

,

alzheimer disease

,

endometrial neoplasms

,

drug-related side effects and adverse reactions

,

peripheral arterial disease

,

peripheral vascular diseases

,

uterine cervical neoplasms

,

acute lung injury

,

newborn respiratory distress syndrome

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

respiratory aspiration

,

alveolar soft part sarcoma

,

inflammatory breast neoplasms

,

aplastic anemia

,

t-cell lymphoma peripheral

,

,

graft vs host disease

,

rheumatoid arthritis

,

intestinal neoplasms

,

endometrioid carcinoma

,

merkel cell carcinoma

,

squamous cell neoplasms

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

neuroendocrine tumors

,

severe acute respiratory syndrome

,

carcinoma in situ

,

ductal carcinoma breast

,

,

cystic fibrosis

,

nontuberculous mycobacterium infections

,

mycobacterium infections

,

pancreatic ductal carcinoma

,

myelomonocytic leukemia acute

,

transitional cell carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

myeloid leukemia accelerated phase

,

residual neoplasm

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

gastrointestinal neoplasms

,

immunologic deficiency syndromes

,

t-cell lymphoma

,

immunoglobulin light-chain amyloidosis

,

,

lymphoproliferative disorders

,

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

biliary tract neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

,

adenocarcinoma in situ

,

,

cognitive dysfunction

,

,

severe acute respiratory syndrome-related coronavirus

,

,

unilateral breast neoplasms

,

hypersensitivity

,

kidney diseases

,

kidney transplantation

,

critical illness

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

invasive hydatidiform mole

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

bile duct neoplasms

,

laryngeal neoplasms

,

burkitt lymphoma

,

ulcerative colitis

,

,

,

urologic neoplasms

,

,

,

,

,

soft tissue neoplasms

,

breast neoplasms

,

prostatic neoplasms

,

multiple myeloma

,

myeloid leukemia

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

,

non-hodgkin lymphoma

,

,

,

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

pancreatic neoplasms

,

,

pulmonary alveolar proteinosis

,

renal cell carcinoma

,

,

uveal neoplasms

,

,

autoimmune diseases

,

communicable diseases

,

,

triple negative breast neoplasms

,

rhabdomyosarcoma

,

,

,

cutaneous malignant melanoma

,

refractory anemia

,

head and neck neoplasms

,

,

ganglioneuroblastoma

,

,

large b-cell lymphoma diffuse

,

refractory anemia with excess of blasts

,

hematologic diseases

,

,

urinary bladder neoplasms

,

radiation effects

,

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

coronavirus infections

,

,

,

invasive fungal infections

,

,

,

tongue neoplasms

,

,

,

,

,

myeloid leukemia acute

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

chronic hepatitis b

,

,

,

chronic hepatitis

,

,

,

,

wounds and injuries

,

,

respiratory insufficiency

,

bone marrow failure disorders

,

,

liver cirrhosis

,

graft rejection

,

,

multiple myeloma

,

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

gata2 deficiency

,

,

hepatocellular carcinoma

,

liver neoplasms

,

non-small-cell lung carcinoma

,

,

,

myeloid leukemia

,

head and neck neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

philadelphia chromosome

,

graft rejection

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

ischemic stroke

,

,

,

,

,

,

atrial fibrillation

,

,

,

,

hyperbilirubinemia

,

,

,

acquired immunodeficiency syndrome

,

communicable diseases

,

esophageal neoplasms

,

esophageal squamous cell carcinoma

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

follicular lymphoma

,

mantle-cell lymphoma

,

b-cell lymphoma

,

rheumatoid arthritis

,

acute coronary syndrome

,

coronary artery disease

,

hypertrophic cardiomyopathy

,

cardiomyopathies

,

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