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Company ReportsKaryopharm Therapeutics

Karyopharm Therapeutics(KPTI)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Xpovio	Selinexor	2019-07-03	2032-2035	Multiple myeloma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neoplasm metastasis

,

precursor cell lymphoblastic leukemia-lymphoma

,

hematologic neoplasms

,

lymphoid leukemia

,

renal cell carcinoma

,

fallopian tube neoplasms

,

,

cutaneous malignant melanoma

,

rectal neoplasms

,

,

,

stomach neoplasms

,

esophageal neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia

,

biphenotypic leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

,

endometrial stromal sarcoma

,

hodgkin disease

,

brain neoplasms

,

nervous system neoplasms

,

,

immunoglobulin light-chain amyloidosis

,

hepatocellular carcinoma

,

liver neoplasms

,

phenylketonurias

,

,

,

non-hodgkin lymphoma

,

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

myelodysplastic syndromes

,

,

,

ovarian neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

triple negative breast neoplasms

,

,

colorectal neoplasms

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

,

,

central nervous system neoplasms

,

squamous cell neoplasms

,

alveolar soft part sarcoma

,

prostatic neoplasms

,

mantle-cell lymphoma

,

coronavirus infections

,

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

small cell lung carcinoma

,

,

,

thrombocytopenia

,

drug-related side effects and adverse reactions

,

gastrointestinal stromal tumors

,

maximum tolerated dose

,

recreational drug use

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

acinar cell carcinoma

,

essential thrombocythemia

,

polycythemia vera

,

,

,

squamous cell carcinoma

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

waldenstrom macroglobulinemia

,

urologic neoplasms

,

transitional cell carcinoma

,

,

communicable diseases

,

,

,

,

t-cell lymphoma cutaneous

,

neuroendocrine carcinoma

,

uterine cervical neoplasms

,

,

diffuse intrinsic pontine glioma

,

smoldering multiple myeloma

,

ovarian epithelial carcinoma

,

,

adipose tissue neoplasms

,

extranodal nk-t-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia acute

,

,

myeloid leukemia

,

,

,

primary myelofibrosis

,

endometrial neoplasms

,

,

,

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

salivary gland neoplasms

multiple myeloma

,

plasma cell neoplasms

multiple myeloma

,

plasma cell neoplasms

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

central nervous system neoplasms

,

breast neoplasms

,

triple negative breast neoplasms

,

,

myelodysplastic syndromes

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

breast neoplasms

,

triple negative breast neoplasms

,

,

cytomegalovirus retinitis

,

Aglatimagene besadenovec

renal cell carcinoma

,

colonic neoplasms

,

,

urethral neoplasms

,

transitional cell carcinoma

,

neuroendocrine carcinoma

,

,

,

non-small-cell lung carcinoma

,

urinary bladder neoplasms

,

urologic neoplasms

,

small cell lung carcinoma

,

breast neoplasms

,

,

,

neuroendocrine tumors

,

ovarian neoplasms

,

uterine cervical neoplasms

,

small cell carcinoma

,

,

triple negative breast neoplasms

,

colorectal neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

squamous cell carcinoma

,

,

disease progression

,

squamous cell carcinoma of head and neck

,

,

pancreatic neoplasms

,

endometrial neoplasms

,

stomach neoplasms

,

head and neck neoplasms

,

esophageal neoplasms

,

ovarian epithelial carcinoma

,

hypersensitivity

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

prostatic hyperplasia

,

,

disease susceptibility

healthy volunteers/patients

,

,

breast neoplasms

,

chemotherapy-induced febrile neutropenia

,

febrile neutropenia

cerebral small vessel diseases

colorectal neoplasms

,

pancreatic ductal carcinoma

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

multiple myeloma

,

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

,

,

breast neoplasms

,

triple negative breast neoplasms

,

invasive hydatidiform mole

,

sickle cell anemia

,

Calcium dobesilate

colorectal neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

non-small-cell lung carcinoma

,

,

multiple myeloma

,

plasma cell neoplasms

,

neoplasm metastasis

Sodium chloride

,

,

,

,

,

,

depressive disorder

,

,

streptococcal infections

,

streptococcus agalactiae

,

,

acute kidney injury

,

wounds and injuries

,

,

,

aplastic anemia

,

,

hematologic neoplasms

,

,

cutaneous malignant melanoma

,

major depressive disorder

,

suicidal ideation

,

stomach neoplasms

,

bacterial infections

,

gram-positive bacterial infections

,

diabetic nephropathies

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

parkinson disease

,

healthy volunteers/patients

,

peritoneal neoplasms

,

intestinal obstruction

,

triple negative breast neoplasms

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

somatoform disorders

,

,

,

congenital hyperinsulinism

,

nesidioblastosis

,

hyperinsulinism

,

,

eosinophilic esophagitis

,

,

sickle cell anemia

,

treatment-resistant depressive disorder

,

meningococcal infections

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

,

non-small-cell lung carcinoma

,

,

homozygous familial hypercholesterolemia

,

,

meningococcal meningitis

,

cardiovascular diseases

,

,

kidney diseases

,

renal cell carcinoma

,

,

cystic fibrosis

,

prostatic neoplasms

,

,

,

pancreatic neoplasms

,

chronic renal insufficiency

,

kidney transplantation

,

graft rejection

,

,

,

,

,

japanese encephalitis

,

respiratory tract infections

,

,

,

metabolic bone diseases

,

,

,

pulmonary eosinophilia

,

hepatocellular carcinoma

,

liver neoplasms

,

gastrointestinal stromal tumors

,

atherosclerosis

,

,

,

diabetes complications

,

vitreous hemorrhage

,

,

essential hypertension

,

metabolic syndrome

,

,

,

systolic murmurs

,

isolated systolic hypertension

,

neoplasm metastasis

,

,

human influenza

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

hypersensitivity

,

left ventricular hypertrophy

,

,

,

,

communicable diseases

,

,

diabetic retinopathy

,

,

insulin resistance

,

prehypertension

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

type 2 diabetes mellitus

,

,

,

retinal diseases

,

hip osteoarthritis

,

,

food hypersensitivity

,

abdominal obesity

,

retinal neovascularization

,

pathologic neovascularization

,

migraine disorders

,

migraine without aura

,

angina pectoris

,

microvascular angina

,

,

migraine with aura

,

health risk behaviors

,

vascular stiffness

gram-positive bacterial infections

,

healthy volunteers/patients

,

precursor cell lymphoblastic leukemia-lymphoma

,

philadelphia chromosome

,

kidney neoplasms

,

plexiform neurofibroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

brain neoplasms

,

ovarian neoplasms

,

triple negative breast neoplasms

,

prostatic neoplasms

,

pancreatic neoplasms

,

stomach neoplasms

,

,

uterine cervical neoplasms

,

,

neuroendocrine tumors

,

neoplasm metastasis

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

urinary bladder neoplasms

,

pneumococcal infections

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

,

non-hodgkin lymphoma

,

castration-resistant prostatic neoplasms

,

malignant mesothelioma

,

,

biliary tract neoplasms

,

neuroendocrine carcinoma

,

thyroid neoplasms

,

,

central nervous system neoplasms

,

uterine neoplasms

,

uveal neoplasms

,

cutaneous malignant melanoma

,

alveolar soft part sarcoma

,

thymus neoplasms

,

gastrointestinal stromal tumors

,

central nervous system diseases

,

,

chronic hepatitis c

,

pancreatic ductal carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

hodgkin disease

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

hairy cell leukemia

,

reactive arthritis

,

burkitt lymphoma

,

merkel cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

,

mullerian mixed tumor

,

salivary gland neoplasms

,

adenoid cystic carcinoma

,

female genital neoplasms

,

clear cell adenocarcinoma

,

adenomyoepithelioma

,

,

islet cell adenoma

,

squamous cell neoplasms

,

thyroid diseases

,

,

nervous system neoplasms

,

endometrioid carcinoma

,

colonic neoplasms

,

colonic diseases

,

respiratory tract infections

,

papillomaviridae

,

,

,

acquired immunodeficiency syndrome

,

myeloid leukemia acute

,

second primary neoplasms

,

,

,

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

squamous cell carcinoma of head and neck

,

hepatocellular carcinoma

,

colorectal neoplasms

,

squamous cell carcinoma

,

liver neoplasms

,

endometrial neoplasms

,

esophageal neoplasms

,

,

,

,

bacterial infections

,

hematologic neoplasms

,

esophageal squamous cell carcinoma

,

,

,

multiple myeloma

,

transitional cell carcinoma

,

,

b-cell chronic lymphocytic leukemia

,

,

bacterial pneumonia

,

papillomavirus infections

,

communicable diseases

,

hypercholesterolemia

,

lymphoid leukemia

,

plasma cell neoplasms

,

,

bacterial vaginosis

,

vulvovaginal candidiasis

,

vaginal diseases

,

disease progression

,

urologic neoplasms

,

ventilator-associated pneumonia

,

iatrogenic disease

,

,

migraine disorders

,

persistent infection

,

hyperlipoproteinemia type ii

,

,

,

,

,

,

,

,

haemophilus infections

,

,

,

,

cardiovascular diseases

,

atherosclerosis

,

,

,

hepatitis a virus

,

,

cystic fibrosis

,

,

,

metabolic syndrome

,

,

,

bipolar disorder

,

myeloid leukemia

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

plasma cell neoplasms

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