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Karyopharm Therapeutics
Karyopharm Therapeutics
(KPTI)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Xpovio
Selinexor
2019-07-03
2032-2035
Multiple myeloma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Selinexor
neoplasm metastasis
,
biphenotypic leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
hematologic neoplasms
,
lymphoid leukemia
,
renal cell carcinoma
,
fallopian tube neoplasms
,
skin neoplasms
,
cutaneous malignant melanoma
,
rectal neoplasms
,
aggression
,
ewing sarcoma
,
stomach neoplasms
,
esophageal neoplasms
,
gliosarcoma
,
chromosome aberrations
,
b-cell chronic lymphocytic leukemia
,
prolymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
blast crisis
,
leiomyosarcoma
,
endometrial stromal sarcoma
,
hodgkin disease
,
brain neoplasms
,
nervous system neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
hepatocellular carcinoma
,
liver neoplasms
,
phenylketonurias
,
hematopoietic stem cell transplantation
,
sarcoma
,
non-hodgkin lymphoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
myelodysplastic syndromes
,
carcinoma
,
glioblastoma
,
ovarian neoplasms
,
preleukemia
,
syndrome
,
breast neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
lung neoplasms
,
melanoma
,
colorectal neoplasms
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
glioma
,
small cell lung carcinoma
,
central nervous system neoplasms
,
squamous cell neoplasms
,
alveolar soft part sarcoma
,
adenocarcinoma
,
pancreatic ductal carcinoma
,
prostatic neoplasms
,
mantle-cell lymphoma
,
coronavirus infections
,
thymoma
,
glandular and epithelial neoplasms
,
thymus neoplasms
,
rhabdoid tumor
,
thrombocytopenia
,
myoepithelioma
,
drug-related side effects and adverse reactions
,
gastrointestinal stromal tumors
,
maximum tolerated dose
,
recreational drug use
,
pancreatic neoplasms
,
acinar cell carcinoma
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
squamous cell carcinoma
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
waldenstrom macroglobulinemia
,
urologic neoplasms
,
transitional cell carcinoma
,
infections
,
communicable diseases
,
diabetic foot
,
ulcer
,
foot ulcer
,
t-cell lymphoma cutaneous
,
neuroendocrine carcinoma
,
uterine cervical neoplasms
,
smoldering multiple myeloma
,
residual neoplasm
,
ovarian epithelial carcinoma
,
wilms tumor
,
osteosarcoma
,
fibrosarcoma
,
hemangiosarcoma
,
benign fibrous histiocytoma
,
histiocytoma
,
extranodal nk-t-cell lymphoma
,
ductal carcinoma
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia juvenile
,
multiple myeloma
,
plasma cell neoplasms
,
myeloid leukemia acute
,
recurrence
,
neoplasms
,
leukemia
,
myeloid leukemia
,
primary myelofibrosis
,
endometrial neoplasms
,
liposarcoma
,
covid-19
,
virus diseases
,
myeloproliferative disorders
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
salivary gland neoplasms
,
mothers
Belantamab
multiple myeloma
,
plasma cell neoplasms
,
recurrence
Mafodotin
renal insufficiency
,
carcinoma
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
smoldering multiple myeloma
,
autoimmune diseases
,
neoplasms
,
corneal diseases
,
follicular lymphoma
,
hematologic diseases
,
blood protein disorders
,
paraproteinemias
,
immunoglobulin light-chain amyloidosis
,
recurrence
,
lymphoma
,
large b-cell lymphoma diffuse
,
large-cell lymphoma anaplastic
,
plasmablastic lymphoma
,
b-cell lymphoma
,
glioma
,
amyloidosis
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
multiple myeloma
,
plasma cell neoplasms
,
glioblastoma
,
brain neoplasms
,
gliosarcoma
,
sepsis
,
agranulocytosis
,
opportunistic infections
Docusate
digestive system neoplasms
,
ovarian epithelial carcinoma
,
myelodysplastic syndromes
,
breast neoplasms
,
neoplasms
,
myeloproliferative disorders
,
primary myelofibrosis
,
lymphoma
,
leukemia
,
prostatic neoplasms
,
colorectal neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
non-hodgkin lymphoma
,
multiple myeloma
,
glioblastoma
,
large b-cell lymphoma diffuse
,
myeloid leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
prolymphocytic leukemia
,
refractory anemia with excess of blasts
,
b-cell leukemia
Benzimidazole
healthy volunteers/patients
,
rheumatoid arthritis
,
arthritis
,
drug interactions
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
alzheimer disease
,
prostatic neoplasms
,
carcinoma
,
small cell carcinoma
,
neuroendocrine carcinoma
,
hodgkin disease
,
lymphoma
,
neoplasms
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
hematoma
,
graft rejection
,
atrial fibrillation
,
thrombosis
,
embolism
Cilmostim
sarcoma
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
neoplasms
,
synovitis
,
giant cell tumors
,
pigmented villonodular synovitis
,
giant cell tumor of tendon sheath
Aglatimagene besadenovec
glioblastoma
,
glioma
,
recurrence
,
renal cell carcinoma
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
melanoma
,
kidney neoplasms
,
small cell carcinoma
,
neoplasms
,
castration-resistant prostatic neoplasms
,
neoplasm metastasis
,
adenocarcinoma
,
prostatic diseases
,
carcinoma
,
urogenital neoplasms
,
male genital neoplasms
,
neuroendocrine carcinoma
,
neoplasms by site
,
hypersensitivity
,
x-linked bulbo-spinal atrophy
,
glandular and epithelial neoplasms
,
male genital diseases
,
genital diseases
,
endometrial neoplasms
,
prostatic neoplasms
Lenograstim
multiple myeloma
Edrecolomab
neoplasm metastasis
,
non-small-cell lung carcinoma
,
urologic neoplasms
,
urinary bladder neoplasms
,
ureteral neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
triple negative breast neoplasms
,
uterine cervical neoplasms
,
prostatic neoplasms
,
esophageal neoplasms
,
squamous cell carcinoma of head and neck
,
pelvic neoplasms
,
lung neoplasms
,
colorectal neoplasms
,
breast neoplasms
,
endometrial neoplasms
,
adenocarcinoma
,
squamous cell carcinoma
,
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
brain neoplasms
,
glioblastoma
,
neuroblastoma
,
glioma
,
osteosarcoma
,
medulloblastoma
,
rhabdoid tumor
,
ependymoma
,
ewing sarcoma
,
rhabdomyosarcoma
,
diffuse intrinsic pontine glioma
,
hearing loss
,
sensorineural hearing loss
,
bilateral hearing loss
,
deafness
Calcium dobesilate
waldenstrom macroglobulinemia
Phenylalanine
multiple myeloma
,
dyskinesias
,
type 2 diabetes mellitus
,
parkinson disease
,
insulin resistance
,
dyslipidemias
,
hyperglycemia
Doconexent
waldenstrom macroglobulinemia
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
philadelphia chromosome
,
lymphoid leukemia
,
head and neck neoplasms
,
myeloid leukemia acute
,
gata2 deficiency
,
plasma cell neoplasms
,
non-small-cell lung carcinoma
,
neoplasms
,
non-hodgkin lymphoma
,
glioblastoma
,
esophageal neoplasms
,
carcinoma
,
squamous cell carcinoma
,
squamous cell neoplasms
,
lung neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
adenocarcinoma of lung
,
bronchiolo-alveolar adenocarcinoma
,
prostatic neoplasms
,
neoplasm metastasis
,
recurrence
,
multiple myeloma
,
hodgkin disease
,
residual neoplasm
,
lymphoma
Lornoxicam
b-cell lymphoma
,
inflammatory breast neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
myeloproliferative disorders
,
primary myelofibrosis
,
promyelocytic leukemia acute
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia acute
,
myelomonocytic leukemia juvenile
,
acute disease
,
systemic scleroderma
,
diffuse scleroderma
,
sclerosis
,
large b-cell lymphoma diffuse
,
leukemia
,
myeloid leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
non-hodgkin lymphoma
,
lymphoid leukemia
,
lymphoma
,
myeloid leukemia
,
myelodysplastic syndromes
,
multiple myeloma
,
plasma cell neoplasms
,
bcr-abl positive chronic myelogenous leukemia
,
preleukemia
,
neoplasms
,
b-cell chronic lymphocytic leukemia
,
triple negative breast neoplasms
,
refractory anemia with excess of blasts
,
renal insufficiency
,
hematologic diseases
,
blood protein disorders
,
neoplasms by histologic type
,
paraproteinemias
,
hodgkin disease
,
diabetes mellitus
,
type 1 diabetes mellitus
,
prolymphocytic leukemia t-cell
,
prolymphocytic leukemia
,
recurrence
,
burkitt lymphoma
,
graft vs host disease
,
bronchiolitis obliterans syndrome
,
aplastic anemia
,
breast neoplasms
,
brain stem neoplasms
,
glycogen storage disease type ii
,
glycogen storage disease type iii
,
ovarian neoplasms
,
hematologic neoplasms
Molgramostim
recurrence
,
lymphoma
,
central nervous system neoplasms
,
medulloblastoma
,
burkitt lymphoma
,
astrocytoma
,
choroid plexus neoplasms
,
optic nerve glioma
,
oligodendroglioma
,
interdigitating dendritic cell sarcoma
,
sarcoma
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
neoplasms
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
synovitis
,
giant cell tumors
,
pigmented villonodular synovitis
,
giant cell tumor of tendon sheath
Aspartame
mucopolysaccharidosis iv
,
mucopolysaccharidoses
,
phenylketonurias
,
hypersensitivity
,
achondroplasia
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