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Karyopharm Therapeutics
Karyopharm Therapeutics
(KPTI)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Xpovio
Selinexor
2019-07-03
2032-2035
Multiple myeloma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Selinexor
neoplasm metastasis
,
biphenotypic leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
hematologic neoplasms
,
renal cell carcinoma
,
fallopian tube neoplasms
,
skin neoplasms
,
cutaneous malignant melanoma
,
rectal neoplasms
,
aggression
,
ewing sarcoma
,
stomach neoplasms
,
esophageal neoplasms
,
gliosarcoma
,
chromosome aberrations
,
b-cell chronic lymphocytic leukemia
,
prolymphocytic leukemia
,
lymphoid leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
endometrial stromal sarcoma
,
hodgkin disease
,
brain neoplasms
,
nervous system neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
hepatocellular carcinoma
,
liver neoplasms
,
phenylketonurias
,
hematopoietic stem cell transplantation
,
sarcoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
myelodysplastic syndromes
,
carcinoma
,
non-hodgkin lymphoma
,
glioblastoma
,
ovarian neoplasms
,
neurofibrosarcoma
,
extranodal nk-t-cell lymphoma
,
central nervous system neoplasms
,
preleukemia
,
syndrome
,
breast neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
lung neoplasms
,
melanoma
,
colorectal neoplasms
,
nerve sheath neoplasms
,
glioma
,
glandular and epithelial neoplasms
,
small cell lung carcinoma
,
thrombocytopenia
,
squamous cell neoplasms
,
alveolar soft part sarcoma
,
adenocarcinoma
,
pancreatic ductal carcinoma
,
prostatic neoplasms
,
leiomyosarcoma
,
coronavirus infections
,
thymoma
,
thymus neoplasms
,
rhabdoid tumor
,
myoepithelioma
,
drug-related side effects and adverse reactions
,
gastrointestinal stromal tumors
,
maximum tolerated dose
,
recreational drug use
,
pancreatic neoplasms
,
acinar cell carcinoma
,
squamous cell carcinoma
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
waldenstrom macroglobulinemia
,
urologic neoplasms
,
transitional cell carcinoma
,
infections
,
communicable diseases
,
diabetic foot
,
ulcer
,
foot ulcer
,
t-cell lymphoma cutaneous
,
neuroendocrine carcinoma
,
uterine cervical neoplasms
,
smoldering multiple myeloma
,
residual neoplasm
,
ovarian epithelial carcinoma
,
wilms tumor
,
osteosarcoma
,
chondrosarcoma
,
clear cell sarcoma
,
fibrosarcoma
,
hemangiosarcoma
,
epithelioid hemangioendothelioma
,
synovial sarcoma
,
myxoid liposarcoma
,
benign fibrous histiocytoma
,
glomus tumor
,
disorders of sex development
,
dermatofibrosarcoma
,
adipose tissue neoplasms
,
granular cell tumor
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia juvenile
,
anemia
,
refractory anemia with excess of blasts
,
multiple myeloma
,
plasma cell neoplasms
,
myeloid leukemia acute
,
recurrence
,
neoplasms
,
leukemia
,
myeloid leukemia
,
primary myelofibrosis
,
endometrial neoplasms
,
liposarcoma
,
covid-19
,
myeloproliferative disorders
,
virus diseases
,
uterine neoplasms
,
neoplasms by site
,
uterine diseases
,
genital diseases
,
epstein-barr virus infections
,
hemophagocytic lymphohistiocytosis
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
mantle-cell lymphoma
,
salivary gland neoplasms
,
mothers
,
myeloid sarcoma
Belantamab
multiple myeloma
,
recurrence
,
neoplasms
Mafodotin
chronic kidney failure
,
renal insufficiency
,
carcinoma
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
autoimmune diseases
,
recurrence
,
neoplasms
,
corneal diseases
,
immunoglobulin light-chain amyloidosis
,
follicular lymphoma
,
hematologic diseases
,
blood protein disorders
,
paraproteinemias
,
lymphoma
,
large b-cell lymphoma diffuse
,
amyloidosis
,
residual neoplasm
,
large-cell lymphoma anaplastic
,
plasmablastic lymphoma
,
b-cell lymphoma
,
glioma
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
multiple myeloma
,
plasma cell neoplasms
,
glioblastoma
,
brain neoplasms
,
gliosarcoma
,
sepsis
,
agranulocytosis
,
opportunistic infections
Docusate
type 2 diabetes mellitus
,
diabetes mellitus
Benzimidazole
healthy volunteers/patients
,
drug interactions
,
atopic dermatitis
,
eczema
,
dermatitis
,
multiple myeloma
,
plasma cell neoplasms
,
papillary thyroid cancer
,
autoimmune diseases
,
amyloidosis
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
Cilmostim
neutropenia
,
breast neoplasms
Enoblituzumab
leukemia
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
mantle-cell lymphoma
,
lymphoid leukemia
,
renal cell carcinoma
,
kidney neoplasms
,
lung neoplasms
,
prostatic neoplasms
Aglatimagene besadenovec
prostatic hyperplasia
,
hyperplasia
,
erectile dysfunction
Lenograstim
lymphoma
,
stomach neoplasms
,
adenocarcinoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
glioma
,
central nervous system neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
leukemia
,
myelodysplastic syndromes
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia
,
preleukemia
,
syndrome
Edrecolomab
anemia
,
anxiety disorders
,
depressive disorder
,
heart failure
,
hepatitis b
,
hepatitis
,
hepatitis a
,
multiple myeloma
,
plasma cell neoplasms
,
chronic hepatitis b
,
human influenza
,
chronic hepatitis
,
urinary tract infections
,
escherichia coli infections
,
restless legs syndrome
,
psychomotor agitation
,
syndrome
Calcium dobesilate
castration-resistant prostatic neoplasms
,
non-hodgkin lymphoma
,
colorectal neoplasms
,
multiple myeloma
,
recurrence
,
plasma cell neoplasms
,
prostatic neoplasms
,
neoplasms
,
vomiting
,
nausea
,
drug-related side effects and adverse reactions
,
sarcoma
Phenylalanine
hematologic neoplasms
,
neoplasms
,
large b-cell lymphoma diffuse
,
phenylketonurias
,
multiple myeloma
,
type 2 diabetes mellitus
,
diabetes mellitus
Doconexent
waldenstrom macroglobulinemia
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
philadelphia chromosome
,
lymphoid leukemia
,
head and neck neoplasms
,
myeloid leukemia acute
,
gata2 deficiency
,
non-small-cell lung carcinoma
,
glioblastoma
,
esophageal neoplasms
,
carcinoma
,
squamous cell carcinoma
,
squamous cell neoplasms
,
lung neoplasms
,
non-hodgkin lymphoma
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
plasma cell neoplasms
,
adenocarcinoma of lung
,
bronchiolo-alveolar adenocarcinoma
,
prostatic neoplasms
,
neoplasms
,
neoplasm metastasis
,
recurrence
,
multiple myeloma
,
hodgkin disease
,
residual neoplasm
,
lymphoma
Lornoxicam
b-cell lymphoma
,
inflammatory breast neoplasms
,
immunoglobulin light-chain amyloidosis
,
myeloproliferative disorders
,
primary myelofibrosis
,
promyelocytic leukemia acute
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia acute
,
myelomonocytic leukemia juvenile
,
acute disease
,
systemic scleroderma
,
diffuse scleroderma
,
sclerosis
,
large b-cell lymphoma diffuse
,
leukemia
,
myeloid leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
non-hodgkin lymphoma
,
lymphoid leukemia
,
lymphoma
,
myeloid leukemia
,
myelodysplastic syndromes
,
multiple myeloma
,
plasma cell neoplasms
,
bcr-abl positive chronic myelogenous leukemia
,
preleukemia
,
neoplasms
,
b-cell chronic lymphocytic leukemia
,
triple negative breast neoplasms
,
refractory anemia with excess of blasts
,
renal insufficiency
,
hematologic diseases
,
blood protein disorders
,
neoplasms by histologic type
,
paraproteinemias
,
hodgkin disease
,
diabetes mellitus
,
type 1 diabetes mellitus
,
prolymphocytic leukemia t-cell
,
prolymphocytic leukemia
,
recurrence
,
burkitt lymphoma
,
graft vs host disease
,
bronchiolitis obliterans syndrome
,
aplastic anemia
,
breast neoplasms
,
brain stem neoplasms
,
glycogen storage disease type ii
,
glycogen storage disease type iii
,
ovarian neoplasms
,
hematologic neoplasms
Molgramostim
leukemia
,
lymphoma
,
prostatic neoplasms
,
melanoma
,
b-cell chronic lymphocytic leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloproliferative disorders
,
myeloid leukemia
,
preleukemia
,
non-hodgkin lymphoma
,
biphenotypic leukemia acute
,
syndrome
,
multiple myeloma
,
hematologic diseases
,
anemia
,
hodgkin disease
,
aplastic anemia
,
renal cell carcinoma
,
carcinoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
breast neoplasms
,
animal mammary neoplasms
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
follicular lymphoma
,
lymphoid leukemia
,
hepatocellular carcinoma
,
liver neoplasms
,
pneumococcal pneumonia
,
ovarian neoplasms
,
fallopian tube neoplasms
,
urinary bladder neoplasms
,
neoplasm metastasis
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