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Karyopharm Therapeutics
Karyopharm Therapeutics
(KPTI)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Xpovio
Selinexor
2019-07-03
2032-2035
Multiple myeloma
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Selinexor
sarcoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
hematologic neoplasms
,
recurrence
,
non-hodgkin lymphoma
,
aggression
,
biphenotypic leukemia acute
,
bcr-abl positive chronic myelogenous leukemia
,
blast crisis
,
acute disease
,
alveolar soft part sarcoma
,
ewing sarcoma
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
immunoglobulin light-chain amyloidosis
,
b-cell chronic lymphocytic leukemia
,
prolymphocytic leukemia
,
mantle-cell lymphoma
,
rectal neoplasms
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
neoplasms
,
lung neoplasms
,
colorectal neoplasms
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
non-small-cell lung carcinoma
,
melanoma
,
glioblastoma
,
squamous cell neoplasms
,
covid-19
,
coronavirus infections
,
ovarian neoplasms
,
amyloidosis
,
thymoma
,
glandular and epithelial neoplasms
,
thymus neoplasms
,
squamous cell carcinoma
,
glioma
,
urologic neoplasms
,
transitional cell carcinoma
,
infections
,
communicable diseases
,
diabetic foot
,
ulcer
,
foot ulcer
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
t-cell lymphoma cutaneous
,
prostatic neoplasms
,
uterine cervical neoplasms
,
smoldering multiple myeloma
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
ovarian epithelial carcinoma
,
thrombocytopenia
,
breast neoplasms
,
triple negative breast neoplasms
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
lymphoma
,
large b-cell lymphoma diffuse
,
carcinoma
,
b-cell lymphoma
,
primary myelofibrosis
,
endometrial neoplasms
,
liposarcoma
Belantamab
multiple myeloma
,
plasma cell neoplasms
Mafodotin
multiple myeloma
,
plasma cell neoplasms
Docusate
asthma
,
bipolar disorder
,
heart failure
,
type 2 diabetes mellitus
,
diabetes mellitus
,
multiple myeloma
,
plasma cell neoplasms
,
malaria
,
falciparum malaria
,
covid-19
,
sars-cov-2
,
streptococcal infections
,
human influenza
,
infections
,
hiv infections
,
acquired immunodeficiency syndrome
,
migraine disorders
,
headache
,
skin care
Tbo-filgrastim
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
myelodysplastic syndromes
,
bcr-abl positive chronic myelogenous leukemia
,
preleukemia
,
syndrome
,
stem cell transplantation
,
multiple myeloma
,
plasma cell neoplasms
,
breast neoplasms
,
non-hodgkin lymphoma
,
lymphoma
,
lung neoplasms
Vitamin e
hypertension
,
type 2 diabetes mellitus
,
renal insufficiency
,
alzheimer disease
,
colorectal neoplasms
,
non-hodgkin lymphoma
,
hodgkin disease
,
isolated systolic hypertension
,
chronic hepatitis b
,
hiv infections
,
hiv
,
acquired immunodeficiency syndrome
,
immunologic deficiency syndromes
,
chronic renal insufficiency
,
malaria
,
healthy volunteers/patients
,
hepatitis c
,
hepatitis
,
chronic hepatitis c
,
hepatitis a
,
neoplasms
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
sars-cov-2
Cilmostim
breast neoplasms
,
triple negative breast neoplasms
,
hiv infections
,
cytomegalovirus retinitis
,
retinitis
Aglatimagene besadenovec
venous thromboembolism
,
thromboembolism
Lenograstim
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
diabetes mellitus
,
type 1 diabetes mellitus
,
hodgkin disease
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
stomach neoplasms
,
esophageal neoplasms
,
adenocarcinoma
,
bcr-abl positive chronic myelogenous leukemia
,
anemia
,
aplastic anemia
,
stem cell transplantation
,
hematopoietic stem cell transplantation
,
multiple myeloma
,
plasma cell neoplasms
,
breast neoplasms
,
lymphoma
,
non-hodgkin lymphoma
,
prostatic neoplasms
,
neutropenia
,
neoplasms
,
autologous transplantation
,
lung neoplasms
Edrecolomab
hypertension
,
hiv infections
,
hiv
,
acquired immunodeficiency syndrome
,
immunologic deficiency syndromes
,
neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
breast neoplasms
,
renal cell carcinoma
,
urologic neoplasms
,
carcinoma
,
stomach neoplasms
,
head and neck neoplasms
,
melanoma
,
hepatitis c
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
malignant mesothelioma
,
mesothelioma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
transitional cell carcinoma
,
invasive hydatidiform mole
Calcium dobesilate
cataract
,
keratitis
,
blepharitis
,
conjunctivitis
,
allergic conjunctivitis
,
sjogren's syndrome
,
dry eye syndromes
,
eye diseases
Doconexent
restless legs syndrome
,
psychomotor agitation
,
neoplasms
,
uterine cervical neoplasms
,
depression
,
multiple myeloma
,
hematologic diseases
,
blood protein disorders
,
plasma cell neoplasms
,
paraproteinemias
,
corneal diseases
,
drug resistance
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
sarcoma
,
synovial sarcoma
,
falciparum malaria
,
heat stress disorders
,
mood disorders
,
combat disorders
,
traumatic stress disorders
,
covid-19
,
healthy volunteers/patients
,
proteinuria
,
focal segmental glomerulosclerosis
,
sickle cell anemia
,
beta-thalassemia
,
thalassemia
,
sickle cell trait
,
myocardial infarction
,
infarction
,
human influenza
,
malaria
,
breast neoplasms
,
vivax malaria
,
rheumatoid arthritis
,
arthritis
,
asthma
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
heart failure
,
hypertriglyceridemia
,
atrial fibrillation
,
virus diseases
,
inflammation
,
tick-borne encephalitis
,
encephalitis
,
hiv infections
,
rabies
,
mitochondrial diseases
,
mitral valve insufficiency
,
hypertrophy
,
liver diseases
,
non-alcoholic fatty liver disease
,
fatty liver
,
wasting syndrome
,
cachexia
,
nasal polyps
,
polyps
,
infections
,
cytomegalovirus infections
,
communicable diseases
,
gastrointestinal diseases
,
digestive system diseases
,
depressive disorder
Lornoxicam
neuroblastoma
,
bone neoplasms
,
kidney neoplasms
,
follicular lymphoma
,
melanoma
,
neoplasms
,
sarcoma
,
hodgkin disease
,
pancreatic neoplasms
,
ovarian neoplasms
,
recurrence
,
carcinoma
,
adenocarcinoma
,
central nervous system neoplasms
,
sclerosis
,
invasive hydatidiform mole
,
heart diseases
,
osteosarcoma
,
ewing sarcoma
,
primitive neuroectodermal tumors
,
primitive neuroectodermal tumors peripheral
,
neuroectodermal tumors
,
synovial sarcoma
,
fallopian tube neoplasms
,
epstein-barr virus infections
,
stomach neoplasms
,
colorectal neoplasms
,
t-cell lymphoma
,
glioma
,
nervous system neoplasms
,
non-small-cell lung carcinoma
,
hepatocellular carcinoma
,
urinary bladder neoplasms
,
liver neoplasms
,
microsatellite instability
,
renal cell carcinoma
,
lymphoma
,
triple negative breast neoplasms
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
non-hodgkin lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
leukemia
,
lymphoid leukemia
,
hiv infections
,
b-cell chronic lymphocytic leukemia
,
breast neoplasms
,
vomiting
,
nausea
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
infections
,
cytomegalovirus infections
,
communicable diseases
Sodium chloride
depression
,
major depressive disorder
,
depressive disorder
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
,
alzheimer disease
,
systemic lupus erythematosus
,
perceptual disorders
,
confusion
,
schizophrenia
,
infertility
,
acquired immunodeficiency syndrome
,
hiv
,
immunologic deficiency syndromes
,
viral hemorrhagic fevers
,
respiratory syncytial viruses
,
respiratory syncytial virus infections
,
human influenza
,
healthy volunteers/patients
,
ebola hemorrhagic fever
,
hiv infections
,
virus diseases
,
prostatic neoplasms
,
rumination syndrome
,
treatment-resistant depressive disorder
,
postoperative complications
,
thyroid neoplasms
,
goiter
Aspartame
healthy volunteers/patients
,
renal insufficiency
,
chronic kidney failure
,
myeloid leukemia acute
,
immunoassay
,
myelodysplastic syndromes
,
non-hodgkin lymphoma
,
hiv
,
acquired immunodeficiency syndrome
,
immunologic deficiency syndromes
,
psoriatic arthritis
,
myeloid leukemia
,
acute disease
,
virus diseases
,
respiratory syncytial virus infections
,
precursor cell lymphoblastic leukemia-lymphoma
,
respiratory syncytial viruses
,
thrombosis
,
venous thrombosis
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
smoldering multiple myeloma
,
hiv-1
,
neoplasm metastasis
,
liver diseases
,
hepatitis c
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
breast neoplasms
,
postmenopause
,
peripheral nervous system diseases
,
hematologic neoplasms
,
colorectal neoplasms
,
myositis
,
graft vs host disease
,
bronchiolitis obliterans syndrome
,
multiple myeloma
,
plasma cell neoplasms
,
psoriasis
,
non-small-cell lung carcinoma
,
infections
,
hiv infections
,
leukemia
,
communicable diseases
,
neoplasms
,
heart failure
,
stroke
,
lymphoma
,
lymphoid leukemia
,
depression
,
depressive disorder
,
ovarian neoplasms
,
recurrence
,
juvenile arthritis
,
arthritis
,
respiratory tract infections
,
covid-19
,
major depressive disorder
,
treatment-resistant depressive disorder
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
ovarian epithelial carcinoma
,
b-cell chronic lymphocytic leukemia
,
respiratory insufficiency
,
rheumatic diseases
,
collagen diseases
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
tinea
,
tinea pedis
,
psychotic disorders
,
bipolar disorder
,
psychotic affective disorders
,
mood disorders
,
mental disorders
,
human influenza
,
venous thromboembolism
,
thromboembolism
,
schizophrenia
,
type 2 diabetes mellitus
,
crohn disease
,
diabetes mellitus
,
prostatic neoplasms
,
urogenital neoplasms
,
male genital diseases
,
male genital neoplasms
,
genital diseases
,
lung neoplasms
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
cognitive dysfunction
,
thyroid neoplasms
,
papillary thyroid cancer
,
thyroid diseases
,
goiter
,
obesity
,
retinal diseases
,
ankle injuries
,
ankle fractures
,
bone fractures
,
joint dislocations
,
fibula fractures
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