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Drug ReportsMezigdomide
Mezigdomide
Mezigdomide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
21 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101C90.0107213
Plasma cell neoplasmsD054219107213
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients516
Liver diseasesD008107HP_0002910K70-K7711
Hepatic insufficiencyD04855011
Renal insufficiencyD051437HP_0000083N1911
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMezigdomide
INNmezigdomide
Description
Mezigdomide is a cereblon E3 ligase modulator developed by Bristol Myers Squibb to treat multiple myeloma.
Classification
Small molecule
Drug classthalidomide derivatives: zinc finger protein degradation inducing thalidomide derivatives
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Structure (InChI/SMILES or Protein Sequence)
N#Cc1ccc(N2CCN(Cc3ccc(COc4cccc5c4CN([C@H]4CCC(=O)NC4=O)C5=O)cc3)CC2)c(F)c1
Identifiers
PDB
CAS-ID2259648-80-9
RxCUI
ChEMBL IDCHEMBL4648616
ChEBI ID
PubChem CID137379043
DrugBank
UNII IDLA88IH4O02 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 69 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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11 adverse events reported
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