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Trade Name	Drug Name	Approved	Patent Expires	Indication
Tiglutik	Riluzole	2018-09-05	2024-2029	Amyotrophic lateral sclerosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Hyaluronate sodium

knee osteoarthritis

,

,

blood coagulation disorders

,

hemostatic disorders

,

drug interactions

,

pharmacokinetics

,

,

interstitial lung diseases

,

cardiovascular diseases

,

,

non-alcoholic fatty liver disease

,

,

prostatic neoplasms

,

,

,

respiratory syncytial virus infections

,

,

alzheimer disease

,

systemic scleroderma

,

localized scleroderma

,

diffuse scleroderma

,

,

hepatic insufficiency

,

chronic kidney failure

,

pituitary acth hypersecretion

,

cushing syndrome

,

,

colorectal neoplasms

,

,

non-small-cell lung carcinoma

,

,

therapeutic equivalency

,

transient ischemic attack

,

,

heart valve prosthesis

,

staphylococcus aureus

,

cardiac catheterization

,

,

multi-infarct dementia

,

healthy volunteers/patients

,

intracranial hemorrhages

,

cerebral hemorrhage

,

intracranial thrombosis

,

,

,

replacement arthroplasty knee

,

intracranial sinus thrombosis

,

,

wounds and injuries

,

periodontal diseases

,

subdural hematoma

,

patent foramen ovale

,

secondary prevention

,

neoplasm metastasis

,

,

knee osteoarthritis

,

,

replacement arthroplasty hip

,

traumatic intracranial hemorrhage

,

cerebrovascular disorders

,

hypertensive intracranial hemorrhage

,

subarachnoid hemorrhage

,

cerebral intraventricular hemorrhage

,

cerebral small vessel diseases

,

electric countershock

,

migraine disorders

,

,

,

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

,

,

,

ischemic stroke

,

venous thrombosis

,

,

,

coronary artery disease

,

coronary disease

,

myocardial ischemia

,

pulmonary embolism

,

cerebral infarction

,

,

acute coronary syndrome

,

myocardial infarction

,

renal insufficiency

,

,

drug-related side effects and adverse reactions

,

heart valve diseases

,

,

cognitive dysfunction

,

atherosclerosis

,

replacement arthroplasty

,

,

chronic renal insufficiency

,

diabetes mellitus

,

,

percutaneous coronary intervention

,

staphylococcal infections

,

,

st elevation myocardial infarction

,

aortic valve disease

,

aortic valve stenosis

,

pathologic constriction

,

mitral valve stenosis

,

kidney diseases

,

ventricular tachycardia

,

ventricular premature complexes

,

intracranial embolism and thrombosis

,

angina pectoris

,

,

non-st elevated myocardial infarction

,

unstable angina

,

embolism and thrombosis

,

,

type 2 diabetes mellitus

,

,

cognition disorders

,

,

,

,

communicable diseases

,

,

postoperative hemorrhage

,

arterial occlusive diseases

,

postoperative complications

,

therapeutic chemoembolization

,

postphlebitic syndrome

,

postthrombotic syndrome

,

hip osteoarthritis

,

,

blood coagulation tests

,

medication adherence

,

vascular diseases

,

,

oral surgical procedures

,

,

uterine hemorrhage

,

antiphospholipid syndrome

,

myeloproliferative disorders

,

craniocerebral trauma

,

,

retinal vein occlusion

,

stomatognathic diseases

,

liver cirrhosis

,

thrombotic stroke

,

hemorrhagic disorders

,

recreational drug use

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

atrial remodeling

,

,

subdural hematoma chronic

,

,

intracranial arteriosclerosis

,

carotid stenosis

,

,

aortic diseases

Antithrombin iii

streptococcal infections

,

rectal neoplasms

,

,

atrial fibrillation

,

mantle-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colonic neoplasms

,

streptococcus agalactiae

,

breast neoplasms

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

non-small-cell lung carcinoma

,

,

prostatic neoplasms

,

psoriatic arthritis

,

meningococcal infections

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

sickle cell anemia

,

,

renal cell carcinoma

,

,

,

vision disorders

,

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

,

neuroendocrine tumors

,

,

myeloid leukemia

,

ovarian neoplasms

,

human influenza

,

myelodysplastic syndromes

,

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

hepatocellular carcinoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gastrointestinal stromal tumors

,

philadelphia chromosome

,

ovarian epithelial carcinoma

,

axial spondyloarthritis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

graft vs host disease

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

rheumatoid arthritis

,

,

,

,

,

,

haemophilus influenzae

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

hodgkin disease

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

follicular lymphoma

,

pancreatic neoplasms

,

,

myeloid leukemia chronic-phase

,

neuroendocrine carcinoma

,

,

,

essential hypertension

,

systolic murmurs

,

multiple sclerosis

,

neoplasm metastasis

,

chronic progressive multiple sclerosis

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

,

,

neuroendocrine tumors

,

neoplasm metastasis

,

,

b-cell chronic lymphocytic leukemia

,

multiple hamartoma syndrome

,

carcinoid tumor

,

aplastic anemia

,

,

oligodendroglioma

,

,

,

,

cerebellar neoplasms

,

brain neoplasms

,

hepatocellular carcinoma

,

endometrial neoplasms

,

pancreatic neoplasms

,

neuroendocrine carcinoma

,

islet cell carcinoma

,

atopic dermatitis

,

,

,

hodgkin disease

,

,

rheumatoid arthritis

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

neurofibromatosis 2

,

neurofibromatosis 1

,

neurofibromatoses

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

tuberous sclerosis

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

,

myeloproliferative disorders

,

essential thrombocythemia

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

colorectal neoplasms

,

kidney neoplasms

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

psoriatic arthritis

,

renal cell carcinoma

,

,

,

,

,

,

,

meningococcal meningitis

,

prostatic neoplasms

,

organ transplantation

,

graft rejection

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

paroxysmal hemoglobinuria

,

,

chronic urticaria

,

,

hypersensitivity

,

food hypersensitivity

,

peanut hypersensitivity

,

juvenile arthritis

,

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

,

,

,

,

,

attention deficit disorder with hyperactivity

,

,

,

major depressive disorder

,

depressive disorder

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

heart transplantation

,

bone resorption

,

,

,

myeloid leukemia

,

kidney transplantation

,

breast neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

meningococcal infections

,

,

sickle cell anemia

,

liver transplantation

,

multiple sclerosis

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gastrointestinal stromal tumors

,

myeloid leukemia acute

,

human influenza

,

macular degeneration

,

lymphoid leukemia

,

,

,

alzheimer disease

,

choroidal neovascularization

,

pathologic neovascularization

,

,

beta-thalassemia

,

,

parkinson disease

,

relapsing-remitting multiple sclerosis

,

dry eye syndromes

,

type 2 diabetes mellitus

,

diabetes mellitus

,

polycythemia vera

,

primary myelofibrosis

,

graft vs host disease

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

myeloid leukemia chronic-phase

,

,

myelodysplastic syndromes

,

,

,

wet macular degeneration

,

,

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

pulmonary aspergillosis

,

retinal detachment

,

vascular diseases

,

dissociative disorders

,

polypoidal choroidal vasculopathy

,

diabetic retinopathy

,

pneumococcal infections

,

hemochromatosis

,

,

philadelphia chromosome

,

,

stomach neoplasms

,

,

ankylosing spondylitis

,

spondylarthritis

,

neuroendocrine tumors

Nadroparin calcium

,

thromboembolism

healthy volunteers/patients

,

renal insufficiency

,

pharmacokinetics

,

biological availability

,

,

,

,

chronic kidney failure

,

kidney diseases

,

therapeutic equivalency

,

cardiovascular diseases

,

bariatric surgery

,

thromboembolism

,

venous thromboembolism

,

,

acute coronary syndrome

,

,

,

myocardial infarction

,

myocardial ischemia

,

,

,

transcatheter aortic valve replacement

,

,

percutaneous coronary intervention

,

unstable angina

,

knee osteoarthritis

,

hip osteoarthritis

,

,

,

,

coronavirus infections

,

,

respiratory insufficiency

,

communicable diseases

,

rheumatic diseases

,

collagen diseases

,

coronary disease

,

,

intracranial arteriosclerosis

,

arteriosclerosis

,

atrial fibrillation

,

,

,

venous thrombosis

,

pulmonary embolism

,

coronary artery disease

,

peripheral arterial disease

,

,

peripheral vascular diseases

,

,

disease progression

,

,

,

replacement arthroplasty knee

,

replacement arthroplasty hip

,

congenital heart defects

,

,

fontan procedure

Sodium chloride

,

,

,

,

,

,

depressive disorder

,

,

streptococcal infections

,

streptococcus agalactiae

,

,

acute kidney injury

,

wounds and injuries

,

,

,

aplastic anemia

,

,

hematologic neoplasms

,

,

cutaneous malignant melanoma

,

major depressive disorder

,

suicidal ideation

,

stomach neoplasms

,

bacterial infections

,

gram-positive bacterial infections

,

diabetic nephropathies

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

parkinson disease

,

healthy volunteers/patients

,

peritoneal neoplasms

,

intestinal obstruction

,

triple negative breast neoplasms

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

somatoform disorders

,

,

,

congenital hyperinsulinism

,

nesidioblastosis

,

hyperinsulinism

,

,

eosinophilic esophagitis

,

,

sickle cell anemia

,

treatment-resistant depressive disorder

,

meningococcal infections

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

,

non-small-cell lung carcinoma

,

,

homozygous familial hypercholesterolemia

,

,

meningococcal meningitis

,

cardiovascular diseases

,

,

kidney diseases

,

renal cell carcinoma

,

,

cystic fibrosis

,

prostatic neoplasms

,

,

,

pancreatic neoplasms

,

chronic renal insufficiency

,

kidney transplantation

,

graft rejection

,

,

,

,

,

japanese encephalitis

,

respiratory tract infections

,

,

,

metabolic bone diseases

,

,

,

pulmonary eosinophilia

,

hepatocellular carcinoma

,

liver neoplasms

,

gastrointestinal stromal tumors

,

atherosclerosis

,

,

,

diabetes complications

,

vitreous hemorrhage

,

,

essential hypertension

,

metabolic syndrome

,

,

,

systolic murmurs

,

isolated systolic hypertension

,

neoplasm metastasis

,

,

human influenza

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

hypersensitivity

,

left ventricular hypertrophy

,

,

,

,

communicable diseases

,

,

diabetic retinopathy

,

,

insulin resistance

,

prehypertension

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

type 2 diabetes mellitus

,

,

,

retinal diseases

,

hip osteoarthritis

,

,

food hypersensitivity

,

abdominal obesity

,

retinal neovascularization

,

pathologic neovascularization

,

migraine disorders

,

migraine without aura

,

angina pectoris

,

microvascular angina

,

,

migraine with aura

,

health risk behaviors

,

vascular stiffness

healthy volunteers/patients

,

hepatic insufficiency

,

esophageal neoplasms

,

,

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

bronchiolitis obliterans syndrome

,

congenital abnormalities

,

chromosome aberrations

,

brain stem neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

,

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

ganglioneuroblastoma

,

neuroectodermal tumors

,

phenylketonurias

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

ureteral neoplasms

,

pelvic neoplasms

,

adenoid cystic carcinoma

,

metabolic syndrome

,

follicular lymphoma

,

,

pancreatic neoplasms

,

kidney neoplasms

,

,

prostatic neoplasms

,

,

,

head and neck neoplasms

,

neurofibromatoses

,

,

liver neoplasms

,

,

,

neurofibromatosis 1

,

plexiform neurofibroma

,

systemic scleroderma

,

diffuse scleroderma

,

b-cell chronic lymphocytic leukemia

,

,

hematologic neoplasms

,

endometrial neoplasms

,

neuroendocrine carcinoma

,

central nervous system neoplasms

,

ovarian neoplasms

,

mantle-cell lymphoma

,

urinary bladder neoplasms

,

squamous cell carcinoma

,

uterine cervical neoplasms

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

nervous system neoplasms

,

hypereosinophilic syndrome

,

systemic mastocytosis

,

,

uveal neoplasms

,

squamous cell carcinoma of head and neck

,

t-cell lymphoma

,

transitional cell carcinoma

,

primary myelofibrosis

,

,

graft vs host disease

,

adenocarcinoma of lung

,

diffuse intrinsic pontine glioma

,

disease progression

,

oligodendroglioma

,

neurofibromatosis 2

,

acoustic neuroma

,

,

hodgkin disease

,

islet cell carcinoma

,

hematologic diseases

,

myeloid leukemia accelerated phase

,

,

mast-cell leukemia

,

,

germ cell and embryonal neoplasms

,

,

anaplastic thyroid carcinoma

,

t-cell lymphoma peripheral

,

waldenstrom macroglobulinemia

,

castration-resistant prostatic neoplasms

,

,

cholangiocarcinoma

,

chronic disease

,

large-cell lymphoma anaplastic

,

plasma cell granuloma

,

,

,

,

,

gouty arthritis

,

endocrine gland neoplasms

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

sjogren's syndrome

,

retinitis pigmentosa

,

,

,

giant cell tumors

,

pigmented villonodular synovitis

,

giant cell tumor of tendon sheath

,

choroidal neovascularization

,

pathologic neovascularization

,

hemangioblastoma

,

von hippel-lindau disease

,

inflammatory breast neoplasms

,

invasive hydatidiform mole

,

multidrug-resistant tuberculosis

,

local neoplasm recurrence

,

t-cell lymphoma cutaneous

,

peutz-jeghers syndrome

,

acute coronary syndrome

,

st elevation myocardial infarction

,

malignant mesothelioma

,

,

type 1 diabetes mellitus

,

,

intestinal neoplasms

,

testicular neoplasms

,

,

brain stem infarctions

,

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

carcinoma in situ

,

breast diseases

,

multiple hamartoma syndrome

,

,

urologic neoplasms

,

fallopian tube neoplasms

,

t-cell leukemia

,

localized scleroderma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

ovarian epithelial carcinoma

,

sickle cell anemia

,

streptococcus agalactiae

,

colorectal neoplasms

,

myeloid leukemia acute

,

,

,

neoplasm metastasis

,

brain neoplasms

,

hepatocellular carcinoma

,

,

thyroid neoplasms

,

thyroid diseases

,

chronic urticaria

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

triple negative breast neoplasms

,

,

colonic neoplasms

,

,

carcinoid tumor

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

gastrointestinal neoplasms

,

stomach neoplasms

,

rectal neoplasms

,

,

meningococcal meningitis

,

meningococcal infections

,

rheumatoid arthritis

,

organ transplantation

,

graft rejection

,

digestive system neoplasms

,

cutaneous malignant melanoma

,

,

lymphangioleiomyomatosis

,

lupus nephritis

,

,

hypersensitivity

,

peanut hypersensitivity

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

interstitial lung diseases

,

,

lung transplantation

,

malignant carcinoid syndrome

,

serotonin syndrome

,

food hypersensitivity

,

psoriatic arthritis

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

chronic inducible urticaria

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

myeloid leukemia

,

,

bcr-abl positive chronic myelogenous leukemia

,

breast neoplasms

,

,

,

non-small-cell lung carcinoma

,

renal cell carcinoma

,

,

kidney transplantation

,

philadelphia chromosome

,

lymphoid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia chronic-phase

,

liver transplantation

,

renal insufficiency

,

tuberous sclerosis

,

chronic kidney failure

,

heart transplantation

,

kidney diseases

,

islet cell adenoma

,

,

,

macular degeneration

,

,

,

,

autosomal dominant polycystic kidney

,

communicable diseases

,

polycystic kidney diseases

,

,

diabetes mellitus

,

tick-borne encephalitis

,

,

immunosuppression therapy

,

cytomegalovirus infections

,

,

large cell carcinoma

,

vascular diseases

,

,

,

vision disorders

,

,

type 2 diabetes mellitus

,

cross-sectional studies

,

,

polyomavirus infections

,

cryopyrin-associated periodic syndromes

,

polycythemia vera

,

,

,

systolic heart failure

,

myocardial infarction

,

,

,

inferior wall myocardial infarction

sleep wake disorders

,

,

physiological sexual dysfunction

,

,

premature birth

,

premenstrual syndrome

,

relapsing-remitting multiple sclerosis

,

hereditary hemorrhagic telangiectasia

,

,

,

,

hypersensitivity

,

habitual abortion

,

chronic progressive multiple sclerosis

,

,

multiple sclerosis

,

,

neurogenic urinary bladder

,

pelvic floor disorders

,

atrophic vaginitis

,

,

,

,

,

pelvic organ prolapse

,

breast neoplasms

,

endometrial hyperplasia

,

,

,

urinary tract infections

,

communicable diseases

,

,

,

vulvar vestibulitis

,

kallmann syndrome

,

,

chromosome aberrations

,

chromosome disorders

,

female urogenital diseases

,

urogenital diseases

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

hyaline membrane disease

,

urogenital neoplasms

,

uterine prolapse

,

uterine hemorrhage

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

lymphoid leukemia

,

,

respiratory insufficiency

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

lupus nephritis

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

,

,

pulmonary sarcoidosis

,

b-cell chronic lymphocytic leukemia

,

,

healthy volunteers/patients

,

obstructive lung diseases

,

,

graft rejection

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

,

interstitial lung diseases

,

thrombocytopenic purpura

,

,

nephrotic syndrome

,

,

,

,

follicular lymphoma

,

kidney transplantation

,

,

chronic obstructive pulmonary disease

,

liver transplantation

,

atopic dermatitis

,

,

,

graft vs host disease

,

chronic kidney failure

,

,

cytomegalovirus infections

,

communicable diseases

,

kidney diseases

,

,

renal insufficiency

,

heart transplantation

,

multiple sclerosis

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

relapsing-remitting multiple sclerosis

,

vascular diseases

,

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

pulmonary aspergillosis

,

transplantation

,

,

end stage liver disease

,

,

disease progression

,

drug interactions

,

polycythemia vera

,

,

hodgkin disease

,

,

juvenile arthritis

,

,

myeloproliferative disorders

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

1

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