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Trade Name	Drug Name	Approved	Patent Expires	Indication
Tiglutik	Riluzole	2018-09-05	2024-2029	Amyotrophic lateral sclerosis

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Hyaluronate sodium

,

atopic dermatitis

,

,

,

drug interactions

,

ischemic stroke

,

patent foramen ovale

,

atrial fibrillation

,

thromboembolism

Nadroparin calcium

,

subarachnoid hemorrhage

,

cerebral infarction

,

,

,

,

,

postpartum period

,

,

respiratory insufficiency

,

extracorporeal membrane oxygenation

,

neoplasm metastasis

,

,

,

hepatocellular carcinoma

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

liver neoplasms

,

,

digestive system diseases

,

may-thurner syndrome

,

,

postpartum hemorrhage

,

venous thrombosis

,

,

venous thromboembolism

,

thromboembolism

,

pulmonary embolism

,

liver cirrhosis

,

,

,

,

,

,

chronic kidney failure

,

acute kidney injury

,

renal insufficiency

,

esophageal and gastric varices

,

critical illness

,

,

portal hypertension

,

ischemic stroke

,

,

injection site reaction

,

right ventricular dysfunction

,

multiple organ failure

,

vascular diseases

,

,

,

morphine dependence

,

blood coagulation disorders

,

hemostatic disorders

,

connective tissue diseases

,

undifferentiated connective tissue diseases

,

atrial fibrillation

,

ovarian neoplasms

,

female genital diseases

,

urogenital neoplasms

,

genital diseases

,

esophageal neoplasms

,

,

tissue adhesions

,

,

artificial respiration

,

kidney diseases

,

drug monitoring

healthy volunteers/patients

,

knee osteoarthritis

,

,

,

,

telomeric repeat binding protein 2

,

plexiform neurofibroma

,

neurofibromatoses

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

hypersensitivity

,

hematologic neoplasms

,

urologic neoplasms

,

uveal neoplasms

,

,

,

hepatic insufficiency

,

squamous cell carcinoma

,

rheumatoid arthritis

,

endometrial neoplasms

,

pancreatic neoplasms

,

fallopian tube neoplasms

,

neurofibromatosis 1

,

pancreatic ductal carcinoma

,

oropharyngeal neoplasms

,

squamous cell neoplasms

,

hereditary breast and ovarian cancer syndrome

,

type 1 diabetes mellitus

,

,

lymphoid leukemia

,

hereditary sensory and autonomic neuropathies

,

,

uterine neoplasms

,

adenocarcinoma of lung

,

waldenstrom macroglobulinemia

,

,

rectal neoplasms

,

esophageal squamous cell carcinoma

,

small cell carcinoma

,

mouth neoplasms

,

,

laryngeal neoplasms

,

serous cystadenocarcinoma

,

,

diabetic neuropathies

,

b-cell lymphoma marginal zone

,

neurofibrosarcoma

,

chronic obstructive pulmonary disease

,

parkinson disease

,

urethral neoplasms

,

ureteral neoplasms

,

pelvic neoplasms

,

castration-resistant prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

epstein-barr virus infections

,

,

,

peripheral nervous system diseases

,

,

uterine cervical neoplasms

,

residual neoplasm

,

hodgkin disease

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

pleural effusion

,

malignant pleural effusion

,

myocardial infarction

,

reperfusion injury

,

kidney neoplasms

,

renal cell carcinoma

,

colonic neoplasms

,

reactive arthritis

,

breast neoplasms

,

,

neoplasm metastasis

,

,

ovarian neoplasms

,

colorectal neoplasms

,

non-hodgkin lymphoma

,

hepatocellular carcinoma

,

,

liver neoplasms

,

large b-cell lymphoma diffuse

,

stomach neoplasms

,

small cell lung carcinoma

,

,

squamous cell carcinoma of head and neck

,

,

chronic renal insufficiency

,

biliary tract neoplasms

,

mantle-cell lymphoma

,

esophageal neoplasms

,

head and neck neoplasms

,

,

triple negative breast neoplasms

,

urinary bladder neoplasms

,

b-cell lymphoma

,

,

,

,

multiple myeloma

,

breast diseases

,

,

transitional cell carcinoma

,

cardiovascular diseases

,

chronic kidney failure

,

,

malignant mesothelioma

,

neoplasms by site

,

laryngeal diseases

,

communicable diseases

,

infectious skin diseases

,

,

,

ovarian reserve

,

respiratory syncytial virus infections

,

,

inflammatory bowel diseases

,

pituitary dwarfism

,

hypopituitarism

,

,

gastrointestinal stromal tumors

,

lymphoproliferative disorders

,

unknown primary neoplasms

,

postpartum hemorrhage

,

acute coronary syndrome

,

,

male breast neoplasms

,

non-small-cell lung carcinoma

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

prostatic neoplasms

,

b-cell chronic lymphocytic leukemia

,

,

insulin resistance

,

kidney diseases

,

ovarian epithelial carcinoma

,

b-cell leukemia

,

,

,

,

lymphatic diseases

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

,

,

,

,

bacterial pneumonia

,

,

,

,

,

,

family relations

,

,

polyneuropathies

,

familial amyloid neuropathies

,

amyloid neuropathies

,

familial amyloidosis

,

respiratory syncytial viruses

non-small-cell lung carcinoma

,

,

,

prostatic neoplasms

,

physiological sexual dysfunction

,

healthy volunteers/patients

,

premenstrual syndrome

,

relapsing-remitting multiple sclerosis

,

hereditary hemorrhagic telangiectasia

,

,

hypersensitivity

,

habitual abortion

,

chronic progressive multiple sclerosis

,

,

,

,

multiple sclerosis

,

,

neurogenic urinary bladder

,

pelvic floor disorders

,

atrophic vaginitis

,

,

,

,

,

breast neoplasms

,

,

pelvic organ prolapse

,

,

urinary tract infections

,

,

turner syndrome

,

estrogen replacement therapy

,

hormone replacement therapy

,

spontaneous abortion

,

ovarian hyperstimulation syndrome

,

endometrial hyperplasia

,

,

,

communicable diseases

,

uterine diseases

,

lower urinary tract symptoms

,

,

premature birth

,

,

,

vulvar vestibulitis

,

reproductive behavior

,

kallmann syndrome

,

,

chromosome aberrations

,

chromosome disorders

,

female urogenital diseases

,

urogenital diseases

,

female infertility

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

hyaline membrane disease

,

urogenital neoplasms

,

uterine prolapse

,

uterine hemorrhage

,

,

gender dysphoria

,

blood coagulation

,

,

bacterial vaginosis

Bos taurus adrenal cortex corticosteroids

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

respiratory insufficiency

,

,

bronchiolitis obliterans syndrome

,

giant cell arteritis

,

polymyalgia rheumatica

,

lupus nephritis

,

multiple myeloma

,

breast neoplasms

,

,

,

animal mammary neoplasms

,

ornithine carbamoyltransferase deficiency disease

,

,

,

,

,

pulmonary sarcoidosis

,

,

,

b-cell chronic lymphocytic leukemia

,

hypersensitivity

,

,

healthy volunteers/patients

,

,

,

systemic lupus erythematosus

,

prostatic neoplasms

,

urogenital neoplasms

,

male genital neoplasms

,

hematopoietic stem cell transplantation

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

,

,

obstructive lung diseases

,

,

thrombocytopenic purpura idiopathic

,

psychology rejection

,

graft rejection

,

follicular lymphoma

,

,

thrombocytopenia

,

,

nephrotic syndrome

,

,

,

,

,

kidney transplantation

,

,

chronic obstructive pulmonary disease

,

graft vs host disease

,

liver transplantation

,

atopic dermatitis

,

,

,

renal insufficiency

,

chronic kidney failure

,

kidney diseases

,

cytomegalovirus infections

,

heart transplantation

,

multiple sclerosis

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

communicable diseases

,

,

relapsing-remitting multiple sclerosis

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

transplantation

,

spinal muscular atrophy

,

end stage liver disease

,

,

disease progression

,

,

thromboembolism

,

neoplasm metastasis

,

,

may-thurner syndrome

,

,

venous insufficiency

,

,

congenital abnormalities

,

vascular malformations

,

,

open-angle glaucoma

,

gingival overgrowth

,

,

,

gingival hyperplasia

,

gingival hypertrophy

,

dental pulp diseases

,

stomach neoplasms

,

intra-articular injections

,

striae distensae

,

stomatognathic diseases

,

,

low-level light therapy

,

non-small-cell lung carcinoma

,

,

,

,

respiratory tract diseases

,

respiration disorders

,

alcoholic hepatitis

,

thyroid neoplasms

,

,

,

rotator cuff injuries

,

urinary bladder neoplasms

,

cartilage diseases

,

,

oxidative stress

,

diabetic retinopathy

,

congenital abnormalities

,

,

,

patellofemoral pain syndrome

,

corneal diseases

,

somatoform disorders

,

,

,

lower urinary tract symptoms

,

,

head and neck neoplasms

,

,

non-muscle invasive bladder neoplasms

,

conjunctival diseases

,

fecal incontinence

,

,

sudden hearing loss

,

multiple myeloma

,

plasma cell neoplasms

,

carcinoma in situ

,

,

,

urinary incontinence

,

parkinson disease

,

,

obstructive lung diseases

,

sprains and strains

,

cartilage fractures

,

,

interstitial lung diseases

,

stress urinary incontinence

,

,

stem cell research

,

noise-induced hearing loss

,

meniere disease

,

large b-cell lymphoma diffuse

,

papillary carcinoma

,

pancreatic neoplasms

,

spinal cord injuries

,

bacterial conjunctivitis

,

male breast neoplasms

,

,

squamous cell carcinoma of head and neck

,

voice disorders

,

laryngeal neoplasms

,

hereditary corneal dystrophies

,

,

arterial occlusive diseases

,

chronic limb-threatening ischemia

,

,

alpha 1-antitrypsin deficiency

,

pulmonary emphysema

,

,

,

,

,

multiple endocrine neoplasia type 1

,

facial paralysis

,

,

pulmonary hypertension

,

hidradenitis suppurativa

,

,

basal cell carcinoma

,

basal cell neoplasms

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

intratympanic injection

,

,

ehlers-danlos syndrome

,

lens subluxation

,

musculoskeletal pain

,

joint instability

,

joint dislocations

,

periodontal diseases

,

,

interstitial cystitis

,

type 2 diabetes mellitus

,

carpal tunnel syndrome

,

intervertebral disc degeneration

,

postoperative pain

,

,

,

,

,

capsule opacification

,

colorectal neoplasms

,

trigger finger disorder

,

shoulder impingement syndrome

,

spontaneous abortion

,

,

,

gingival hemorrhage

,

aphthous stomatitis

,

bone resorption

,

premature birth

,

,

erectile dysfunction

,

,

,

radiodermatitis

,

premature ejaculation

,

,

pancreatic ductal carcinoma

,

,

cumulative trauma disorders

,

retinal diseases

,

phacoemulsification

,

,

,

musculoskeletal diseases

,

,

hyperpigmentation

,

tendon entrapment

,

,

ductal carcinoma

,

chronic hepatitis c

,

,

,

oral submucous fibrosis

,

,

dental calculus

,

critical illness

,

,

,

olfactory nerve injuries

,

shoulder injuries

,

retinopathy of prematurity

,

,

prostatic diseases

,

failed back surgery syndrome

,

bronchiolitis obliterans syndrome

,

,

knee osteoarthritis

,

dry eye syndromes

,

keratoconjunctivitis sicca

,

,

,

,

,

,

wounds and injuries

,

,

tissue adhesions

,

temporomandibular joint disorders

,

,

,

,

gingival recession

,

,

,

healthy volunteers/patients

,

,

,

hip osteoarthritis

,

atrophic vaginitis

,

,

,

,

periodontal pocket

,

,

breast neoplasms

,

temporomandibular joint dysfunction syndrome

,

,

diabetes mellitus

,

,

alveolar bone loss

,

meibomian gland dysfunction

,

urinary tract infections

,

dental implants

,

,

,

prostatic neoplasms

,

,

,

chronic periodontitis

,

,

,

,

,

patient satisfaction

,

sjogren's syndrome

,

,

,

,

,

,

postoperative complications

,

keratoconjunctivitis

,

,

,

,

,

,

,

elbow tendinopathy

,

,

,

,

vesico-ureteral reflux

,

,

oral lichen planus

,

,

communicable diseases

,

,

,

anterior cruciate ligament injuries

,

peri-implantitis

,

,

,

allergic conjunctivitis

,

,

chronic obstructive pulmonary disease

,

,

thyroid diseases

,

,

photorefractive keratectomy

,

male infertility

,

,

uterine cervical neoplasms

,

alveolar ridge augmentation

,

,

,

beta-thalassemia

,

,

injection site reaction

,

,

,

,

induced abortion

,

actinic keratosis

,

,

,

graves ophthalmopathy

,

,

cesarean section

,

obstetric delivery

,

,

physiological sexual dysfunction

,

bacterial vaginosis

,

,

rheumatoid arthritis

,

sensorineural hearing loss

,

,

polycystic ovary syndrome

,

,

,

,

procedural pain

,

linear energy transfer

,

,

,

,

depressive disorder

,

re-epithelialization

,

cosmetic techniques

,

uterine diseases

,

retained placenta

,

,

,

intraocular pressure

,

physiological stress

,

breast implantation

,

ethmoid sinusitis

,

,

,

surgical blood loss

,

,

surgical wound dehiscence

,

,

gastrointestinal diseases

,

intestinal diseases

,

,

breast carcinoma in situ

,

,

drug delivery systems

,

gastroesophageal reflux

,

,

vaginal diseases

,

cataract extraction

,

papillomavirus infections

,

peptic esophagitis

,

,

,

rectal neoplasms

,

,

,

vocal cord paralysis

,

,

,

,

,

retinal detachment

,

intratracheal intubation

,

,

,

tooth extraction

,

,

,

penile induration

,

atopic dermatitis

,

venous insufficiency

,

,

,

coronary artery disease

,

,

spinal stenosis

,

,

,

fuchs' endothelial dystrophy

,

furcation defects

,

skin manifestations

,

,

,

,

femoracetabular impingement

,

intervertebral disc displacement

,

refractive errors

,

hypertrophic cicatrix

,

dissociative disorders

,

,

phototoxic dermatitis

,

contact dermatitis

,

photoallergic dermatitis

,

,

neuroendocrine tumors

,

,

penile prosthesis

,

,

,

endometrial neoplasms

,

tibial meniscus injuries

,

retinal vein occlusion

,

,

,

metabolic bone diseases

,

endoscopic mucosal resection

,

,

myofascial pain syndromes

,

nasal obstruction

,

,

,

esophageal neoplasms

,

periodontal attachment loss

,

,

,

,

,

,

,

,

tissue preservation

,

,

,

patient reported outcome measures

,

disease progression

,

peripheral arterial disease

,

peripheral vascular diseases

,

iron-deficiency anemia

,

iron deficiencies

,

,

viral pneumonia

,

,

coronary disease

,

chondromalacia patellae

,

,

allergic rhinitis

,

allergic rhinitis seasonal

,

,

intradermal injections

,

,

hemorrhagic cystitis

,

squamous intraepithelial lesions of the cervix

,

,

male urogenital diseases

,

urogenital diseases

,

,

personal satisfaction

,

,

executive function

,

physical fitness

,

habitual abortion

,

,

,

topical administration

,

endophthalmitis

,

gynecologic surgical procedures

,

precancerous conditions

,

alcoholic liver diseases

,

,

metabolic diseases

,

metabolic syndrome

,

,

high-risk pregnancy

,

stress fractures

,

randomized controlled trials as topic

,

spinal diseases

,

,

,

,

gender dysphoria

,

cerebral infarction

,

,

magnetic resonance angiography

,

,

neurodegenerative diseases

,

,

refractive surgical procedures

,

surgical amputation

,

,

,

,

,

sleep apnea syndromes

,

,

hypersensitivity

,

nociceptive pain

,

,

acute kidney injury

,

gastrointestinal microbiome

,

,

fertilization in vitro

,

deglutition disorders

,

,

,

,

,

,

pleural diseases

,

respiratory system abnormalities

,

cystic fibrosis

,

open abdomen techniques

,

angle-closure glaucoma

,

embryo implantation

,

corneal transplantation

,

,

,

,

,

central nervous system neoplasms

,

kidney neoplasms

,

,

nervous system neoplasms

,

,

body dysmorphic disorders

,

,

premature aging

,

drug-related side effects and adverse reactions

,

choroid diseases

,

,

dental pulp necrosis

,

,

,

multiple abnormalities

,

pityriasis rubra pilaris

,

,

,

,

uterine hemorrhage

,

,

dental pulp exposure

,

afibrinogenemia

,

transitional cell carcinoma

,

corneal opacity

,

,

muscle spasticity

,

non-alcoholic fatty liver disease

,

,

,

tendon injuries

,

,

prostatic hyperplasia

,

,

muscle rigidity

,

,

,

sinus floor augmentation

,

,

,

,

,

,

maxillofacial injuries

,

teratozoospermia

,

ventilator-associated pneumonia

,

cross infection

,

healthcare-associated pneumonia

,

,

,

,

,

suppurative otitis media

,

,

,

dietary supplements

,

follicular lymphoma

,

,

,

otorhinolaryngologic diseases

,

,

pediatric obesity

,

rheumatic diseases

,

rheumatic fever

,

collagen diseases

,

alphapapillomavirus

,

uterine cervical dysplasia

,

subarachnoid hemorrhage

,

acute lung injury

,

plantar fasciitis

,

,

retinal perforations

,

radiofrequency ablation

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

pathologic constriction

,

dentin sensitivity

,

tooth discoloration

,

dental implantation

,

,

,

plastic surgery procedures

,

,

,

general anesthesia

,

vascular malformations

,

,

peripheral nervous system diseases

,

tissue transplantation

,

,

acupuncture therapy

,

,

rotator cuff tear arthropathy

,

premature obstetric labor

,

,

tooth fractures

,

,

colonic neoplasms

,

bone regeneration

,

,

perioral dermatitis

,

,

,

periapical periodontitis

,

,

,

,

,

nasopharyngitis

,

postherpetic neuralgia

,

,

,

neurodermatitis

,

,

,

esophageal squamous cell carcinoma

,

,

fatal familial insomnia

,

edentulous jaw partially

,

neuroinflammatory diseases

,

,

,

fixed orthodontic appliances

,

gingival diseases

,

dental esthetics

,

,

,

1

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